Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: WFRF:(Jacobs David R. Jr.) > Genome-wide associa...

LIBRIS Formathandbok (Information om MARC21)

Fältnamn	Indikatorer	Metadata
000		04825naa a2201117 4500
001		oai:DiVA.org:umu-25443
003		SwePub
008		090818s2009 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-254432 URI
024	7	a https://doi.org/10.1038/ng.4292 DOI
040		a (SwePub)umu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Amundadottir, Laufey4 aut
245	1 0	a Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.
264		c 2009-08-02
264	1	b Springer Science and Business Media LLC,c 2009
338		a print2 rdacarrier
520		a We conducted a two-stage genome-wide association study of pancreatic cancer, a cancer with one of the lowest survival rates worldwide. We genotyped 558,542 SNPs in 1,896 individuals with pancreatic cancer and 1,939 controls drawn from 12 prospective cohorts plus one hospital-based case-control study. We conducted a combined analysis of these groups plus an additional 2,457 affected individuals and 2,654 controls from eight case-control studies, adjusting for study, sex, ancestry and five principal components. We identified an association between a locus on 9q34 and pancreatic cancer marked by the SNP rs505922 (combined P = 5.37 x 10(-8); multiplicative per-allele odds ratio 1.20; 95% confidence interval 1.12-1.28). This SNP maps to the first intron of the ABO blood group gene. Our results are consistent with earlier epidemiologic evidence suggesting that people with blood group O may have a lower risk of pancreatic cancer than those with groups A or B.
700	1	a Kraft, Peter4 aut
700	1	a Stolzenberg-Solomon, Rachael Z4 aut
700	1	a Fuchs, Charles S4 aut
700	1	a Petersen, Gloria M4 aut
700	1	a Arslan, Alan A4 aut
700	1	a Bueno-de-Mesquita, H Bas4 aut
700	1	a Gross, Myron4 aut
700	1	a Helzlsouer, Kathy4 aut
700	1	a Jacobs, Eric J4 aut
700	1	a Lacroix, Andrea4 aut
700	1	a Zheng, Wei4 aut
700	1	a Albanes, Demetrius4 aut
700	1	a Bamlet, William4 aut
700	1	a Berg, Christine D4 aut
700	1	a Berrino, Franco4 aut
700	1	a Bingham, Sheila4 aut
700	1	a Buring, Julie E4 aut
700	1	a Bracci, Paige M4 aut
700	1	a Canzian, Federico4 aut
700	1	a Clavel-Chapelon, Françoise4 aut
700	1	a Clipp, Sandra4 aut
700	1	a Cotterchio, Michelle4 aut
700	1	a de Andrade, Mariza4 aut
700	1	a Duell, Eric J4 aut
700	1	a Fox Jr, John W4 aut
700	1	a Gallinger, Steven4 aut
700	1	a Gaziano, J Michael4 aut
700	1	a Giovannucci, Edward L4 aut
700	1	a Goggins, Michael4 aut
700	1	a González, Carlos A4 aut
700	1	a Hallmans, Göranu Umeå universitet,Näringsforskning4 aut0 (Swepub:umu)goha0001
700	1	a Hankinson, Susan E4 aut
700	1	a Hassan, Manal4 aut
700	1	a Holly, Elizabeth A4 aut
700	1	a Hunter, David J4 aut
700	1	a Hutchinson, Amy4 aut
700	1	a Jackson, Rebecca4 aut
700	1	a Jacobs, Kevin B4 aut
700	1	a Jenab, Mazda4 aut
700	1	a Kaaks, Rudolf4 aut
700	1	a Klein, Alison P4 aut
700	1	a Kooperberg, Charles4 aut
700	1	a Kurtz, Robert C4 aut
700	1	a Li, Donghui4 aut
700	1	a Lynch, Shannon M4 aut
700	1	a Mandelson, Margaret4 aut
700	1	a McWilliams, Robert R4 aut
700	1	a Mendelsohn, Julie B4 aut
700	1	a Michaud, Dominique S4 aut
700	1	a Olson, Sara H4 aut
700	1	a Overvad, Kim4 aut
700	1	a Patel, Alpa V4 aut
700	1	a Peeters, Petra H M4 aut
700	1	a Rajkovic, Aleksandar4 aut
700	1	a Riboli, Elio4 aut
700	1	a Risch, Harvey A4 aut
700	1	a Shu, Xiao-Ou4 aut
700	1	a Thomas, Gilles4 aut
700	1	a Tobias, Geoffrey S4 aut
700	1	a Trichopoulos, Dimitrios4 aut
700	1	a Van Den Eeden, Stephen K4 aut
700	1	a Virtamo, Jarmo4 aut
700	1	a Wactawski-Wende, Jean4 aut
700	1	a Wolpin, Brian M4 aut
700	1	a Yu, Herbert4 aut
700	1	a Yu, Kai4 aut
700	1	a Zeleniuch-Jacquotte, Anne4 aut
700	1	a Chanock, Stephen J4 aut
700	1	a Hartge, Patricia4 aut
700	1	a Hoover, Robert N4 aut
710	2	a Umeå universitetb Näringsforskning4 org
773	0	t Nature Geneticsd : Springer Science and Business Media LLCg 41, s. 986-990q 41<986-990x 1061-4036x 1546-1718
856	4	u https://europepmc.org/articles/pmc2839871?pdf=render
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-25443
856	4 8	u https://doi.org/10.1038/ng.429

Hitta via bibliotek

Nature Genetics (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...: Amundadottir, La ...; Kraft, Peter; Stolzenberg-Solo ...; Fuchs, Charles S; Petersen, Gloria ...; Arslan, Alan A; visa fler...; Bueno-de-Mesquit ...; Gross, Myron; Helzlsouer, Kath ...; Jacobs, Eric J; Lacroix, Andrea; Zheng, Wei; Albanes, Demetri ...; Bamlet, William; Berg, Christine ...; Berrino, Franco; Bingham, Sheila; Buring, Julie E; Bracci, Paige M; Canzian, Federic ...; Clavel-Chapelon, ...; Clipp, Sandra; Cotterchio, Mich ...; de Andrade, Mari ...; Duell, Eric J; Fox Jr, John W; Gallinger, Steve ...; Gaziano, J Micha ...; Giovannucci, Edw ...; Goggins, Michael; González, Carlos ...; Hallmans, Göran; Hankinson, Susan ...; Hassan, Manal; Holly, Elizabeth ...; Hunter, David J; Hutchinson, Amy; Jackson, Rebecca; Jacobs, Kevin B; Jenab, Mazda; Kaaks, Rudolf; Klein, Alison P; Kooperberg, Char ...; Kurtz, Robert C; Li, Donghui; Lynch, Shannon M; Mandelson, Marga ...; McWilliams, Robe ...; Mendelsohn, Juli ...; Michaud, Dominiq ...; Olson, Sara H; Overvad, Kim; Patel, Alpa V; Peeters, Petra H ...; Rajkovic, Aleksa ...; Riboli, Elio; Risch, Harvey A; Shu, Xiao-Ou; Thomas, Gilles; Tobias, Geoffrey ...; Trichopoulos, Di ...; Van Den Eeden, S ...; Virtamo, Jarmo; Wactawski-Wende, ...; Wolpin, Brian M; Yu, Herbert; Yu, Kai; Zeleniuch-Jacquo ...; Chanock, Stephen ...; Hartge, Patricia; Hoover, Robert N; visa färre...

Artiklar i publikationen: Nature Genetics

Av lärosätet: Umeå universitet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se