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A comparison of gen...
A comparison of genome-scans performed in multicase families with systemic lupus erythematosus from different population groups
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- Johanneson, B (author)
- Uppsala universitet,Institutionen för genetik och patologi
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Steinsson, K (author)
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- Lindqvist, A K (author)
- Uppsala universitet,Karolinska Institutet,Institutionen för genetik och patologi
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Kristjansdottir, H (author)
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Grondal, G (author)
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Sandino, S (author)
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- Tjernström, Fredrik (author)
- Lund University,Lunds universitet,Öron-, näs- och halssjukdomar, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Otorhinolaryngology (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Sturfelt, Gunnar (author)
- Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
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Granados-Arriola, J (author)
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Alcocer-Varela, J (author)
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- Lundberg, I (author)
- Karolinska Institutet
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- Jonasson, I (author)
- Uppsala universitet,Institutionen för genetik och patologi
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- Truedsson, Lennart (author)
- Lund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine
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Svenungsson, E (author)
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Klareskog, L (author)
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Alarcon-Segovia, D (author)
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Johanneson, N (author)
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- Gyllensten, UB (author)
- Uppsala universitet,Institutionen för genetik och patologi
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- Alarcon-Riquelme, ME (author)
- Uppsala universitet,Institutionen för genetik och patologi
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(creator_code:org_t)
- Elsevier BV, 1999
- 1999
- English.
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In: Journal of Autoimmunity. - : Elsevier BV. - 0896-8411. ; 13, s. 137-
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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Abstract
Subject headings
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- Systemic lupus erythematosus is a disease of unknown etiology. Multiple genetic factors are believed to be involved in its pathogenesis. In addition, and due to genetic heterogeneity, these factors and/or their combinations may be different in different ethnic groups, while some might be shared between populations. We have performed genome scans in multicase families from three different population groups, two from Northern Europe, with a high degree of homogeneity, and the third from a recently admixed population of Mexican Mestizos. Although our family material is relatively small, the results presented here show that using family sets from well defined populations are sufficient to detect susceptibility loci for SLE. Our results also reveal the chromosomal regions most likely to contain susceptibility genes for SLE.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Keyword
- systemic lupus erythematosus
- genetics
- autoimmunity
- genome-scan
- linkage analysis
Publication and Content Type
- art (subject category)
- ref (subject category)
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To the university's database
- By the author/editor
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Johanneson, B
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Steinsson, K
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Lindqvist, A K
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Kristjansdottir, ...
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Grondal, G
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Sandino, S
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show more...
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Tjernström, Fred ...
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Sturfelt, Gunnar
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Granados-Arriola ...
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Alcocer-Varela, ...
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Lundberg, I
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Jonasson, I
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Truedsson, Lenna ...
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Svenungsson, E
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Klareskog, L
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Alarcon-Segovia, ...
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Johanneson, N
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Gyllensten, UB
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Alarcon-Riquelme ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Rheumatology and ...
- Articles in the publication
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Journal of Autoi ...
- J Autoimmun
- By the university
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Lund University
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Karolinska Institutet
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Uppsala University