Saphenous vein grafts in contemporary coronary artery bypass graft surgery

Caliskan, Etem (författare): Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany; Department of Cardiothoracic and Vascular Surgery, German Heart Institute Berlin, Berlin, Germany

de Souza, Domingos Ramos, 1954- (författare): Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Cardiothoracic and Vascular Surgery

Böning, Andreas (författare): Department of Cardiovascular Surgery, University Hospital Giessen, Giessen, Germany

Liakopoulos, Oliver J. (författare): Department of Cardiac and Thoracic Surgery, Heart Center of the University of Cologne, Cologne, Germany

Choi, Yeong-Hoon (författare): Department of Cardiac and Thoracic Surgery, Heart Center of the University of Cologne, Cologne, Germany

Pepper, John (författare): Department of Cardiothoracic Surgery, Royal Brompton Hospital, London, UK

Gibson, C. Michael (författare): Boston Clinical Research Institute, Boston, MA, USA

Perrault, Louis P. (författare): Department of Cardiac Surgery, Montreal Heart Institute, Université de Montréal, Montreal, Canada

Wolf, Randall K. (författare): DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, TX, USA

Kim, Ki-Bong (författare): Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, South Korea

Emmert, Maximilian Y. (författare): Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany; Department of Cardiothoracic and Vascular Surgery, German Heart Institute Berlin, Berlin, Germany

(creator_code:org_t)

2019-08-27
2020
Engelska.
Ingår i: Nature Reviews Cardiology. - : Nature Publishing Group. - 1759-5002 .- 1759-5010. ; 17:3, s. 155-169

Relaterad länk:: https://urn.kb.se/re...; visa fler...; https://doi.org/10.1...; visa färre...

Abstract Ämnesord

Stäng

Myocardial ischaemia resulting from obstructive coronary artery disease is a major cause of morbidity and mortality in the developed world. Coronary artery bypass graft (CABG) surgery is the gold-standard treatment in many patients with complex multivessel coronary artery disease or left main disease. Despite substantial improvements in the outcome of patients undergoing CABG surgery in the past decade, graft patency remains the 'Achilles' heel' of this procedure. Whereas the use of the left internal mammary artery as a conduit is associated with the highest 10-year patency rate (>90%), saphenous vein grafts - the most commonly used conduit in CABG surgery - fail in 40-50% of treated patients by 10 years after surgery. Vein graft disease (VGD) and failure result from complex pathophysiological processes that can lead to complete occlusion of the graft, affecting long-term clinical outcomes. Optimal harvesting techniques, intraoperative preservation strategies and intraoperative patency control have important roles in the prevention of VGD. In addition, several studies published in the past decade have reported similar mid-term patency rates between vein grafts and arterial grafts when veins are used as a composite graft based on the internal mammary artery. In this Review, we present the latest evidence on the utilization of saphenous vein grafts for CABG surgery and provide an overview of the current practices for the prevention of VGD and vein graft failure.

Av författaren/redakt...: Caliskan, Etem; de Souza, Doming ...; Böning, Andreas; Liakopoulos, Oli ...; Choi, Yeong-Hoon; Pepper, John; visa fler...; Gibson, C. Micha ...; Perrault, Louis ...; Wolf, Randall K.; Kim, Ki-Bong; Emmert, Maximili ...; visa färre...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Kardiologi

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