Search: (WFRF:(Ross Owen A)) srt2:(2015-2019) srt2:(2016) pers:(Revesz Tamas) >
Genome-wide analysi...
Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases.
-
Guerreiro, Rita (author)
-
Escott-Price, Valentina (author)
-
Darwent, Lee (author)
-
show more...
-
Parkkinen, Laura (author)
-
Ansorge, Olaf (author)
-
Hernandez, Dena G (author)
-
Nalls, Michael A (author)
-
Clark, Lorraine (author)
-
Honig, Lawrence (author)
-
Marder, Karen (author)
-
van der Flier, Wiesje (author)
-
Holstege, Henne (author)
-
Louwersheimer, Eva (author)
-
Lemstra, Afina (author)
-
Scheltens, Philip (author)
-
Rogaeva, Ekaterina (author)
-
St George-Hyslop, Peter (author)
-
- Londos, Elisabet (author)
- Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups
-
- Zetterberg, Henrik, 1973 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
-
Ortega-Cubero, Sara (author)
-
Pastor, Pau (author)
-
Ferman, Tanis J (author)
-
Graff-Radford, Neill R (author)
-
Ross, Owen A (author)
-
Barber, Imelda (author)
-
Braae, Anne (author)
-
Brown, Kristelle (author)
-
Morgan, Kevin (author)
-
Maetzler, Walter (author)
-
Berg, Daniela (author)
-
Troakes, Claire (author)
-
Al-Sarraj, Safa (author)
-
Lashley, Tammaryn (author)
-
Compta, Yaroslau (author)
-
Revesz, Tamas (author)
-
Lees, Andrew (author)
-
Cairns, Nigel J (author)
-
Halliday, Glenda M (author)
-
Mann, David (author)
-
Pickering-Brown, Stuart (author)
-
Powell, John (author)
-
Lunnon, Katie (author)
-
Lupton, Michelle K (author)
-
Dickson, Dennis (author)
-
Hardy, John (author)
-
Singleton, Andrew (author)
-
Bras, Jose (author)
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2016
- 2016
- English.
-
In: Neurobiology of Aging. - : Elsevier BV. - 1558-1497 .- 0197-4580. ; 38, s. 7-214
- Related links:
-
http://www.ncbi.nlm....
-
show more...
-
http://dx.doi.org/10... (free)
-
https://doi.org/10.1...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
https://gup.ub.gu.se...
-
show less...
Abstract
Subject headings
Close
- The similarities between dementia with Lewy bodies (DLB) and both Parkinson's disease (PD) and Alzheimer's disease (AD) are many and range from clinical presentation, to neuropathological characteristics, to more recently identified, genetic determinants of risk. Because of these overlapping features, diagnosing DLB is challenging and has clinical implications since some therapeutic agents that are applicable in other diseases have adverse effects in DLB. Having shown that DLB shares some genetic risk with PD and AD, we have now quantified the amount of sharing through the application of genetic correlation estimates, and show that, from a purely genetic perspective, and excluding the strong association at the APOE locus, DLB is equally correlated to AD and PD.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Keyword
- Dementia with Lewy bodies
- Alzheimer's disease
- Parkinson's disease
- Genetic correlation
- heritability
- association
- consortium
- diagnosis
- risk
- Geriatrics & Gerontology
- Neurosciences & Neurology
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database
- By the author/editor
-
Guerreiro, Rita
-
Escott-Price, Va ...
-
Darwent, Lee
-
Parkkinen, Laura
-
Ansorge, Olaf
-
Hernandez, Dena ...
-
show more...
-
Nalls, Michael A
-
Clark, Lorraine
-
Honig, Lawrence
-
Marder, Karen
-
van der Flier, W ...
-
Holstege, Henne
-
Louwersheimer, E ...
-
Lemstra, Afina
-
Scheltens, Phili ...
-
Rogaeva, Ekateri ...
-
St George-Hyslop ...
-
Londos, Elisabet
-
Zetterberg, Henr ...
-
Ortega-Cubero, S ...
-
Pastor, Pau
-
Ferman, Tanis J
-
Graff-Radford, N ...
-
Ross, Owen A
-
Barber, Imelda
-
Braae, Anne
-
Brown, Kristelle
-
Morgan, Kevin
-
Maetzler, Walter
-
Berg, Daniela
-
Troakes, Claire
-
Al-Sarraj, Safa
-
Lashley, Tammary ...
-
Compta, Yaroslau
-
Revesz, Tamas
-
Lees, Andrew
-
Cairns, Nigel J
-
Halliday, Glenda ...
-
Mann, David
-
Pickering-Brown, ...
-
Powell, John
-
Lunnon, Katie
-
Lupton, Michelle ...
-
Dickson, Dennis
-
Hardy, John
-
Singleton, Andre ...
-
Bras, Jose
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Neurology
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Geriatrics
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Neurosciences
- Articles in the publication
-
Neurobiology of ...
- By the university
-
Lund University
-
University of Gothenburg