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Association of Heal...
Association of Healthy Lifestyle With Years Lived Without Major Chronic Diseases
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- Nyberg, Solja T. (author)
- Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland
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- Singh-Manoux, Archana (author)
- Department of Epidemiology and Public Health, University College London, United Kingdom / Inserm U1153, Epidemiology of Ageing and Neurodegenrative Diseases, Paris, France
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- Pentti, Jaana (author)
- Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland / Department of Public Health, University of Turku, Turku University Hospital, Finland / Centre for Population Health Research, University of Turku, Turku University Hospital, Finland
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- Madsen, Ida E. H. (author)
- National Research Centre for the Working Environment, Copenhagen, Denmark
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- Sabia, Severine (author)
- Department of Epidemiology and Public Health, University College London, United Kingdom / Inserm U1153, Epidemiology of Ageing and Neurodegenrative Diseases, Paris, France
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- Alfredsson, Lars (author)
- Karolinska Institutet
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- Bjorner, Jakob B. (author)
- National Research Centre for the Working Environment, Copenhagen, Denmark
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- Borritz, Marianne (author)
- Bispebjerg University Hospital, Copenhagen, Denmark
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- Burr, Hermann (author)
- Federal Institute for Occupational Safety and Health, Berlin, Germany
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- Goldberg, Marcel (author)
- Faculty of Medicine, Paris Descartes University, Paris, France / Inserm UMS 011, Population-Based Epidemiological Cohorts Unit, Villejuif, France
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- Heikkila, Katriina (author)
- Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, United Kingdom
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- Jokela, Markus (author)
- Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Finland
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- Knutsson, Anders, 1942- (author)
- Mittuniversitetet,Institutionen för hälsovetenskap,Department of Health Sciences, Mid Sweden University, Sundsvall, Sweden
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- Lallukka, Tea (author)
- Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland / Finnish Institute of Occupational Health, Helsinki, Finland
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- Lindbohm, Joni (author)
- Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland
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- Nielsen, Martin L. (author)
- AS3 Employment, AS3 Companies, Viby J, Denmark
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- Nordin, Maria (author)
- Umeå universitet,Stockholms universitet,Stressforskningsinstitutet,Stress Research Institute, Stockholm University, Sweden / Department of Psychology, Umeå University, Sweden,Institutionen för psykologi,Stress Research Institute, Stockholm University, Stockholm, Sweden
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- Oksanen, Tuula (author)
- Finnish Institute of Occupational Health, Helsinki, Finland
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- Pejtersen, Jan H. (author)
- VIVE-The Danish Center for Social Science Research, Copenhagen, Denmark
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- Rahkonen, Ossi (author)
- Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland
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- Rugulies, Reiner (author)
- National Research Centre for the Working Environment, Copenhagen, Denmark / Department of Public Health, Department of Psychology, University of Copenhagen, Denmark
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- Shipley, Martin J. (author)
- Department of Epidemiology and Public Health, University College London, United Kingdom
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- Sipila, Pyry N. (author)
- Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland
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- Stenholm, Sari (author)
- Department of Public Health, University of Turku, Turku University Hospital, Finland / Centre for Population Health Research, University of Turku, Turku University Hospital, Finland
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- Suominen, Sakari (author)
- Högskolan i Skövde,Institutionen för hälsovetenskaper,Forskningsmiljön hälsa, hållbarhet och digitalisering,Department of Public Health, University of Turku, Turku University Hospital, Finland,Individ och samhälle (VIDSOC), Individual and society
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- Vahtera, Jussi (author)
- Department of Public Health, University of Turku, Turku University Hospital, Finland / Centre for Population Health Research, University of Turku, Turku University Hospital, Finland
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- Virtanen, Marianna (author)
- Karolinska Institutet
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- Westerlund, Hugo (author)
- Karolinska Institutet,Stockholms universitet,Stressforskningsinstitutet,Stress Research Institute, Stockholm University, Sweden
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- Zins, Marie (author)
- Faculty of Medicine, Paris Descartes University, France / Inserm UMS 011, Population-Based Epidemiological Cohorts Unit, Villejuif, France
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- Hamer, Mark (author)
- Division of Surgery and Interventional Science, Faculty of Medical Sciences, University College London, United Kingdom
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- Batty, G. David (author)
- Department of Epidemiology and Public Health, University College London, United Kingdom / School of Biological and Population Health Sciences, Oregon State University, Corvallis, OR, United States
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- Kivimaki, Mika (author)
- Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland / Department of Epidemiology and Public Health, University College London, United Kingdom
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(creator_code:org_t)
- American Medical Association (AMA), 2020
- 2020
- English.
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In: JAMA Internal Medicine. - : American Medical Association (AMA). - 2168-6106 .- 2168-6114. ; 180:5, s. 760-768
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- This cohort study examines disease-free life-years in participants with varying combinations of lifestyle risk factors.Question: Are different combinations of lifestyle factors associated with years lived without chronic diseases?Findings: In a multicohort study of 116 & x202f;043 participants, a statistically significant association between overall healthy lifestyle score and an increased number of disease-free life-years was noted. Of 16 different lifestyle profiles studied, the 4 that were associated with the greatest disease-free life years included body mass index lower than 25 and at least 2 of 3 factors: never smoking, physical activity, and moderate alcohol consumption.Meaning: Various healthy lifestyle profiles appear to be associated with extended gains in life lived without type 2 diabetes, cardiovascular and respiratory diseases, and cancer.Importance: It is well established that selected lifestyle factors are individually associated with lower risk of chronic diseases, but how combinations of these factors are associated with disease-free life-years is unknown.Objective: To estimate the association between healthy lifestyle and the number of disease-free life-years.Design, Setting, and Participants: A prospective multicohort study, including 12 European studies as part of the Individual-Participant-Data Meta-analysis in Working Populations Consortium, was performed. Participants included 116 & x202f;043 people free of major noncommunicable disease at baseline from August 7, 1991, to May 31, 2006. Data analysis was conducted from May 22, 2018, to January 21, 2020.Exposures: Four baseline lifestyle factors (smoking, body mass index, physical activity, and alcohol consumption) were each allocated a score based on risk status: optimal (2 points), intermediate (1 point), or poor (0 points) resulting in an aggregated lifestyle score ranging from 0 (worst) to 8 (best). Sixteen lifestyle profiles were constructed from combinations of these risk factors.Main Outcomes and Measures: The number of years between ages 40 and 75 years without chronic disease, including type 2 diabetes, coronary heart disease, stroke, cancer, asthma, and chronic obstructive pulmonary disease.Results: Of the 116 & x202f;043 people included in the analysis, the mean (SD) age was 43.7 (10.1) years and 70 & x202f;911 were women (61.1%). During 1.45 million person-years at risk (mean follow-up, 12.5 years; range, 4.9-18.6 years), 17 & x202f;383 participants developed at least 1 chronic disease. There was a linear association between overall healthy lifestyle score and the number of disease-free years, such that a 1-point improvement in the score was associated with an increase of 0.96 (95% CI, 0.83-1.08) disease-free years in men and 0.89 (95% CI, 0.75-1.02) years in women. Comparing the best lifestyle score with the worst lifestyle score was associated with 9.9 (95% CI 6.7-13.1) additional years without chronic diseases in men and 9.4 (95% CI 5.4-13.3) additional years in women (P < .001 for dose-response). All of the 4 lifestyle profiles that were associated with the highest number of disease-free years included a body-mass index less than 25 (calculated as weight in kilograms divided by height in meters squared) and at least 2 of the following factors: never smoking, physical activity, and moderate alcohol consumption. Participants with 1 of these lifestyle profiles reached age 70.3 (95% CI, 69.9-70.8) to 71.4 (95% CI, 70.9-72.0) years disease free depending on the profile and sex.Conclusions and Relevance: In this multicohort analysis, various healthy lifestyle profiles appeared to be associated with gains in life-years without major chronic diseases.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Allmänmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- General Practice (hsv//eng)
Keyword
- life style risk factors
- chronic disease
- multicohort
- Psychology
- psykologi
- Individual and Society VIDSOC
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Nyberg, Solja T.
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Singh-Manoux, Ar ...
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Pentti, Jaana
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Madsen, Ida E. H ...
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Sabia, Severine
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Alfredsson, Lars
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show more...
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Bjorner, Jakob B ...
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Borritz, Mariann ...
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Burr, Hermann
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Goldberg, Marcel
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Heikkila, Katrii ...
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Jokela, Markus
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Knutsson, Anders ...
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Lallukka, Tea
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Lindbohm, Joni
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Nielsen, Martin ...
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Nordin, Maria
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Oksanen, Tuula
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Pejtersen, Jan H ...
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Rahkonen, Ossi
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Rugulies, Reiner
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Shipley, Martin ...
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Sipila, Pyry N.
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Stenholm, Sari
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Suominen, Sakari
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Vahtera, Jussi
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Virtanen, Marian ...
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Westerlund, Hugo
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Zins, Marie
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Hamer, Mark
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Batty, G. David
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Kivimaki, Mika
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
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- SOCIAL SCIENCES
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SOCIAL SCIENCES
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and Psychology
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and General Practice
- Articles in the publication
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JAMA Internal Me ...
- By the university
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Stockholm University
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Umeå University
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Mid Sweden University
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University of Skövde
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Karolinska Institutet