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The use of palliati...
The use of palliative medications before death from prostate cancer: Swedish population-based study with a comparative overview of European data
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- Lycken, Magdalena (författare)
- Uppsala universitet,Urologkirurgi
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- Drevin, L. (författare)
- Reg Canc Ctr Uppsala Örebro Reg, Uppsala, Sweden
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- Garmo, H. (författare)
- Reg Canc Ctr Uppsala Örebro Reg, Uppsala, Sweden.; Kings Coll London, Sch Med, Div Canc Studies, London, England
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- Stattin, Pär (författare)
- Uppsala universitet,Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden,Urologkirurgi,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden
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- Adolfsson, J. (författare)
- Karolinska Institutet,Karolinska Inst, Dept Clin Sci Intervent & Technol, Stockholm, Sweden
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- Franck-Lissbrant, Ingela, 1969 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology,Univ Gothenburg, Sahlgrenska Acad, Inst Clin Sci, Dept Oncol, Gothenburg, Sweden
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- Holmberg, Lars (författare)
- Uppsala universitet,Endokrinkirurgi,Reg Canc Ctr Uppsala Örebro Reg, Uppsala, Sweden.; Kings Coll London, Sch Med, Div Canc Studies, London, England
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- Bill-Axelson, Anna (författare)
- Uppsala universitet,Urologkirurgi
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(creator_code:org_t)
- Elsevier BV, 2018
- 2018
- Engelska.
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Ingår i: European Journal of Cancer. - : Elsevier BV. - 0959-8049 .- 1879-0852. ; 88, s. 101-108
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Abstract
Ämnesord
Stäng
- Background: Symptoms of terminal cancer have previously been reported as under-treated. The aim of this study was to assess the use of palliative medications before death from prostate cancer. Methods: This Swedish register study included men who died from 2009 to 2012 with prostate cancer as the underlying cause of death. We assessed the proportion who collected a prescription of androgen deprivation therapy, non-steroidal anti-inflammatory drugs, paracetamol, opioids, glucocorticoids, antidepressants, anxiolytics and sedative-hypnotics and the differences in treatment related to age, time since diagnosis, educational level, close relatives and comorbidities. Data were collected from 3 years before death from prostate cancer. Results: We included 8326 men. The proportion who received opioids increased from 30% to 72% during the last year of life, and 67% received a strong opioid at the time of death. Antidepressants increased from 13% to 22%, anxiolytics from 9% to 27% and sedative-hypnotics from 21% to 33%. Men without close relatives and older men had lower probability to receive opioids (odds ratio [OR]: 0.56, 95% confidence interval [CI]: 0.47-0.66 for > 85 years versus < 70 years) and (OR 0.78, 95% CI: 0.66-0.92 for unmarried without children versus married with children). Conclusion: Our results represent robust epidemiological data from Sweden for comparison of palliative care quality between countries. The findings indicate that men without close relatives and older men are disadvantaged with respect to the treatment of cancer pain and need closer attention from health care providers and highlight the importance to identify psychological distress in terminal prostate cancer. (C) 2017 Elsevier Ltd. All rights reserved.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Övrig annan medicin och hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Other Medical and Health Sciences not elsewhere specified (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Anxiety
- Cancer pain
- Castration
- Depression
- Fatigue
- Observational study
- Opioids
- Palliative medicine
- Prostate cancer
- Sleep disorders
- last 3 months
- mental-disorders
- pain
- management
- prevalence
- quality
- cohort
- symptoms
- distress
- register
- Oncology
- arlson me
- 1987
- journal of chronic diseases
- v40
- p373
- Anxiety
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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