Sökning: onr:"swepub:oai:gup.ub.gu.se/280055" > Disentangling the g...
Fältnamn | Indikatorer | Metadata |
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000 | 28759naa a2202425 4500 | |
001 | oai:gup.ub.gu.se/280055 | |
003 | SwePub | |
008 | 240910s2019 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:uu-380499 | |
009 | oai:lup.lub.lu.se:88b31e13-d9a4-49a8-a527-d51bd04337b1 | |
024 | 7 | a https://gup.ub.gu.se/publication/2800552 URI |
024 | 7 | a https://doi.org/10.1093/ajcn/nqy2722 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3804992 URI |
024 | 7 | a https://lup.lub.lu.se/record/88b31e13-d9a4-49a8-a527-d51bd04337b12 URI |
040 | a (SwePub)gud (SwePub)uud (SwePub)lu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Karasik, D.u Hebrew Senior Life Inst Aging Res, Boston, MA USA;Harvard Med Sch, Boston, MA 02115 USA;Bar Ilan Univ, Azrieli Fac Med, Safed, Israel,Harvard University,Bar-Ilan University4 aut |
245 | 1 0 | a Disentangling the genetics of lean mass |
264 | 1 | b Elsevier BV,c 2019 |
520 | a Background: Lean body mass (LM) plays an important role in mobility and metabolic function. We previously identified five loci associated with LM adjusted for fat mass in kilograms. Such an adjustment may reduce the power to identify genetic signals having an association with both lean mass and fat mass. Objectives: To determine the impact of different fat mass adjustments on genetic architecture of LM and identify additional LM loci. Methods: We performed genome-wide association analyses for whole-body LM (20 cohorts of European ancestry with n = 38,292) measured using dual-energy X-ray absorptiometry) or bioelectrical impedance analysis, adjusted for sex, age, age(2), and height with or without fat mass adjustments (Model 1 no fat adjustment; Model 2 adjustment for fat mass as a percentage of body mass; Model 3 adjustment for fat mass in kilograms). Results: Seven single-nucleotide polymorphisms (SNPs) in separate loci, including one novel LM locus (TNRC6B), were successfully replicated in an additional 47,227 individuals from 29 cohorts. Based on the strengths of the associations in Model 1 vs Model 3, we divided the LM loci into those with an effect on both lean mass and fat mass in the same direction and refer to those as "sumo wrestler" loci (FTO and MC4R). In contrast, loci with an impact specifically on LMwere termed "body builder" loci (VCAN and ADAMTSL3). Using existing available genome-wide association study databases, LM increasing alleles of SNPs in sumo wrestler loci were associated with an adverse metabolic profile, whereas LM increasing alleles of SNPs in "body builder" loci were associated with metabolic protection. Conclusions: In conclusion, we identified one novel LM locus (TNRC6B). Our results suggest that a genetically determined increase in lean mass might exert either harmful or protective effects on metabolic traits, depending on its relation to fat mass. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
653 | a body composition | |
653 | a skeletal muscle | |
653 | a body fat | |
653 | a meta-analysis of genome-wide association studies | |
653 | a genome-wide association | |
653 | a skeletal-muscle mass | |
653 | a ld score regression | |
653 | a body-mass | |
653 | a susceptibility loci | |
653 | a metaanalysis | |
653 | a insights | |
653 | a density | |
653 | a Nutrition & Dietetics | |
653 | a body composition | |
700 | 1 | a Zillikens, M. C.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Netherlands Genom Initiat, Leiden, Netherlands4 aut |
700 | 1 | a Hsu, Y. H.u Hebrew Senior Life Inst Aging Res, Boston, MA USA;Harvard Med Sch, Boston, MA 02115 USA;Harvard Med Sch, Dept Med, Boston, MA 02115 USA;Harvard Sch Publ Hlth, Mol & Integrat Physiol Sci Program, Boston, MA USA4 aut |
700 | 1 | a Aghdassi, A.u Ernst Moritz Arndt Univ Greifswald, Dept Med A, Greifswald, Germany,Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA,Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15260 USA,Erasmus MC, Dept Clin Genet, Rotterdam, Netherlands;Ctr Med Syst Biol & Netherlands Consortium H, Leiden, Netherlands,Univ Calif Davis, Dept Med, Sacramento, CA 95817 USA,Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Program Personalized & Genom Med, Baltimore, MD 21201 USA;Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Dept Med, Baltimore, MD 21201 USA;Vet Adm Med Ctr, Geriatr Res & Educ Clin Ctr, Baltimore, MD 21218 USA,Vrije Univ Amsterdam Med Ctr, Dept Epidemiol & Biostat, Amsterdam, Netherlands;Vrije Univ Amsterdam Med Ctr, EMGO Inst, Amsterdam, Netherlands4 aut |
700 | 1 | a Åkesson, Kristinau Lund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)orto-kak |
700 | 1 | a Amin, N.u Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut |
700 | 1 | a Barroso, I.u Wellcome Trust Sanger Inst, Wellcome Trust Genome Campus, Hinxton, England;NIHR Cambridge Biomed Res Ctr, Cambridge, England;Univ Cambridge, Metab Res Labs, Inst Metab Sci, Addenbrookes Hosp, Cambridge, England,Washington Univ, Dept Genet, Div Stat Gen, Sch Med, St Louis, MO 63110 USA;Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA4 aut |
700 | 1 | a Bennett, D. A.4 aut |
700 | 1 | a Bertram, L.u Univ Lubeck, Lubeck Interdisciplinary Platform Genome Analyt, Lubeck, Germany,Aarhus Univ Hosp, Endocrinol & Internal Med, Aarhus, Denmark4 aut |
700 | 1 | a Bochud, M.u Lausanne Univ Hosp, Univ Inst Social & Prevent Med, Lausanne, Switzerland4 aut |
700 | 1 | a Borecki, I. B.4 aut |
700 | 1 | a Broer, L.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut |
700 | 1 | a Buchman, A. S.u Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA,Univ Tennessee, Ctr Hlth Sci, Dept Prevent Med, Memphis, TN 38163 USA,Ernst Moritz Arndt Univ Greifswald, Inst Community Med, Greifswald, Germany,Univ Eastern Finland, Dept Med, Kuopio, Finland;Kuopio Univ Hosp, Kuopio, Finland4 aut |
700 | 1 | a Byberg, Liisau Uppsala universitet,Ortopedi4 aut0 (Swepub:uu)liisbybe |
700 | 1 | a Campbell, H.u Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Ctr Global Hlth Res, Teviot Pl, Edinburgh, Midlothian, Scotland4 aut |
700 | 1 | a Campos-Obando, N.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands4 aut |
700 | 1 | a Cauley, J. A.u Natl Inst Hlth & Welfare, Helsinki, Finland4 aut |
700 | 1 | a Cawthon, P. M.u Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA,Columbia Univ, Med Ctr, Ctr Translat & Computat Neuroimmunol Neurol, New York, NY USA,Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Dept Med & Mol Genet, Indianapolis, IN 46202 USA,Natl Inst Hlth & Welfare, Helsinki, Finland;Univ Helsinki, Inst Mol Med, Helsinki, Finland;Diabet & Obes Res Program, Helsinki, Finland;Univ Tartu, Estonian Genome Ctr, Tartu, Estonia4 aut |
700 | 1 | a Chambers, J. C.u Ealing Hosp NHS Trust, Cardiol, London, England;Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England;Imperial Coll Healthcare NHS Trust, London, England;Royal Brompton & Harefield NHS Fdn Trust, NIHR Cardiovasc Biomed Res Unit, London, England;Imperial Coll London, London, England4 aut |
700 | 1 | a Chen, Z.u Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Tucson, AZ USA4 aut |
700 | 1 | a Cho, N. H.u Ajou Univ, Sch Med, Dept Prevent Med, Suwon, South Korea4 aut |
700 | 1 | a Choi, H. J.u Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul, South Korea;Seoul Natl Univ, Coll Med, Neurosci Res Inst, Dept Anat & Cell Biol, Seoul, South Korea;Seoul Natl Univ, Wide River Inst Immunol, Hongcheon, South Korea4 aut |
700 | 1 | a Chou, W. C.u Hebrew Senior Life Inst Aging Res, Boston, MA USA;Harvard Med Sch, Boston, MA 02115 USA;Broad Inst, Cambridge, MA USA,Univ Alabama Birmingham, Dept Epidemiol, Birmingham, AL USA4 aut |
700 | 1 | a Cummings, S. R.u Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA,Wellcome Trust Sanger Inst, Wellcome Trust Genome Campus, Hinxton, England;Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland;Univ Helsinki, Hjelt Inst, Helsinki, Finland4 aut |
700 | 1 | a de Groot, Lcpgm4 aut |
700 | 1 | a Lind, Larsu Uppsala universitet,Klinisk epidemiologi,Univ Western Australia, Sch Med & Pharmacol, Perth, WA, Australia;Sir Charles Gairdner Hosp, Dept Endocrinol & Diabet, Perth, WA, Australia4 aut0 (Swepub:uu)larslind |
700 | 1 | a Demuth, I.u Berlin Inst Hlth, Berlin, Germany;Wageningen Univ, Div Human Nutr, AFSG, Wageningen, Netherlands4 aut |
700 | 1 | a Diatchenko, L.u Univ North Carolina Chapel Hill, Sch Dent, Reg Ctr Neurosensory Disorders, Chapel Hill, NC USA;McGill Univ, Alan Edwards Ctr Res Pain, Montreal, PQ, Canada4 aut |
700 | 1 | a Econs, M. J.u Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Dept Med & Mol Genet, Indianapolis, IN 46202 USA4 aut |
700 | 1 | a Eiriksdottir, G.u Iceland Heart Assoc Holtasmari, Kopavogur, Iceland4 aut |
700 | 1 | a Enneman, A. W.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands4 aut |
700 | 1 | a Eriksson, Joelu Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med & Clin Nutr, Gothenburg, Sweden4 aut0 (Swepub:gu)xerjoe |
700 | 1 | a Eriksson, J. G.u Natl Inst Hlth & Welfare, Helsinki, Finland;Univ Helsinki, Dept Gen Practice & Primary Hlth Care, Helsinki, Finland;Helsinki Univ Cent Hosp, Unit Gen Practice, Helsinki, Finland;Folkhalsan Res Ctr, Helsinki, Finland4 aut |
700 | 1 | a Estrada, K.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Biogen Inc, Translat Biol, 14 Cambridge Ctr, Cambridge, MA 02142 USA,Duke Univ, Sch Med, Dept Med, Duke Mol Physiol Inst, Durham, NC USA;Duke Univ, Sch Med, Dept Med, Div Cardiol, Durham, NC USA4 aut |
700 | 1 | a Evans, D. S.u Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA,Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA4 aut |
700 | 1 | a Feitosa, M. F.u Washington Univ, Dept Genet, Div Stat Gen, Sch Med, St Louis, MO 63110 USA,Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Program Personalized & Genom Med, Baltimore, MD 21201 USA;Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Dept Med, Baltimore, MD 21201 USA4 aut |
700 | 1 | a Fu, M.4 aut |
700 | 1 | a Gieger, C.u Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Genet Epidemiol, Neuherberg, Germany4 aut |
700 | 1 | a Grallert, H.u Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany;Helmholtz Zentrum Munchen, CCG Type 2 Diabet, Neuherberg, Germany;German Ctr Diabet Res, Neuherberg, Germany4 aut |
700 | 1 | a Gudnason, V.u Iceland Heart Assoc Holtasmari, Kopavogur, Iceland;Univ Iceland, Fac Med, Reykjavik, Iceland4 aut |
700 | 1 | a Lenore, L. J.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands,Univ Helsinki, Helsinki Collegium Adv Studies, Helsinki, Finland4 aut |
700 | 1 | a Hayward, C.u Univ Edinburgh, MRC Human Genet Unit, IGMM, Edinburgh, Midlothian, Scotland4 aut |
700 | 1 | a Hofman, A.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Netherlands Genom Initiat, Leiden, Netherlands4 aut |
700 | 1 | a Homuth, G.u Ernst Moritz Arndt Univ Greifswald, Interfac Inst Genet & Funct Gen, Greifswald, Germany4 aut |
700 | 1 | a Michaëlsson, Karl,d 1959-u Uppsala universitet,Ortopedi,Lund Univ, Dept Clin Sci Malmo, Malmo, Sweden,Kings Coll London, Dept Twin Res & Genet Epidemiol, St Thomas Campus, London, England4 aut0 (Swepub:uu)karlmich |
700 | 1 | a Husted, L. B.4 aut |
700 | 1 | a Illig, T.u Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany;Hannover Med Sch, Dept Human Genet, Hannover, Germany4 aut |
700 | 1 | a Ingelsson, E.u Stanford Univ, Sch Med, Dept Med, Div Cardiovasc Med, Stanford, CA USA4 aut |
700 | 1 | a Ittermann, T.u Ernst Moritz Arndt Univ Greifswald, Inst Community Med, Greifswald, Germany4 aut |
700 | 1 | a Jansson, John-Olov,d 1954u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology,Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Physiol, Gothenburg, Sweden4 aut0 (Swepub:gu)xjanjo |
700 | 1 | a Johnson, T.u Lausanne Univ Hosp, Univ Inst Social & Prevent Med, Lausanne, Switzerland;Univ Lausanne, Dept Med Genet, Lausanne, Switzerland;Swiss Inst Bioinformat, Lausanne, Switzerland,Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA4 aut |
700 | 1 | a Biffar, R.u Ernst Moritz Arndt Univ Greifswald, Dept Prosthet Dent Gerodontol & Biomat, Ctr Oral Hlth, Greifswald, Germany4 aut |
700 | 1 | a Jordan, J. M.u Univ North Carolina Chapel Hill, Thurston Arthrit Res Ctr, Chapel Hill, NC USA4 aut |
700 | 1 | a Jula, A.4 aut |
700 | 1 | a Karlsson, Magnusu Lund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)orto-mka |
700 | 1 | a Khaw, K. T.u Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge, England,Univ Eastern Finland, Dept Med, Kuopio, Finland;Kuopio Univ Hosp, Kuopio, Finland4 aut |
700 | 1 | a Kilpelainen, T. O.u Univ Cambridge, MRC Epidemiol Unit, Sch Clin Med, Cambridge Biomed Campus, Cambridge, England;Univ Copenhagen, Fac Hlth & Med Sci, Sect Metabol Genet, Novo Nordisk Fdn Ctr Basic Metab Res, Copenhagen, Denmark;Icahn Sch Med Mt Sinai, Dept Environm Med & Publ Hlth, New York, NY USA4 aut |
700 | 1 | a Klopp, N.u Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany;Hannover Med Sch, Hannover Unified Biobank, Hannover, Germany4 aut |
700 | 1 | a Kloth, J. S. L.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Netherlands Genom Initiat, Leiden, Netherlands4 aut |
700 | 1 | a Koller, D. L.u Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Dept Med & Mol Genet, Indianapolis, IN 46202 USA4 aut |
700 | 1 | a Kooner, J. S.u Ealing Hosp NHS Trust, Cardiol, London, England;Imperial Coll Healthcare NHS Trust, London, England;Imperial Coll London, Hammersmith Hosp, Natl Heart & Lung Inst Cardiovasc Sci, Fac Med, Hammersmith Campus, London, England4 aut |
700 | 1 | a Kraus, W. E.u Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland4 aut |
700 | 1 | a Kritchevsky, S.u Wake Forest Sch Med, Sticht Ctr Hlth Aging & Alzheimers Prevent, Winston Salem, NC USA4 aut |
700 | 1 | a Kutalik, Z.u Lausanne Univ Hosp, Univ Inst Social & Prevent Med, Lausanne, Switzerland;Helmholtz Zentrum Munchen, CCG Nutrigen & Type 2 Diabet, Neuherberg, Germany;Swiss Inst Bioinformat, Lausanne, Switzerland4 aut |
700 | 1 | a Kuulasmaa, T.4 aut |
700 | 1 | a Kuusisto, J.u Univ Eastern Finland, Dept Med, Kuopio, Finland;Kuopio Univ Hosp, Kuopio, Finland4 aut |
700 | 1 | a Laakso, M.u Univ Eastern Finland, Dept Med, Kuopio, Finland;Kuopio Univ Hosp, Kuopio, Finland4 aut |
700 | 1 | a Lahti, J.4 aut |
700 | 1 | a Lang, T.u UC San Francisco, Dept Radiol & Biomed Imaging, San Francisco, CA USA;UC San Francisco, Sch Dent, San Francisco, CA USA4 aut |
700 | 1 | a Langdahl, B. L.u Aarhus Univ Hosp, Endocrinol & Internal Med, Aarhus, Denmark4 aut |
700 | 1 | a Lerch, M. M.u Ernst Moritz Arndt Univ Greifswald, Dept Med A, Greifswald, Germany4 aut |
700 | 1 | a Lewis, J. R.u Univ Western Australia, Sch Med & Pharmacol, Perth, WA, Australia;Univ Sydney, Sydney Med Sch, Sch Publ Hlth, Childrens Hosp Westmead,Ctr Kidney Res, Sydney, NSW, Australia4 aut |
700 | 1 | a Lill, C.u Univ Lubeck, Inst Neurogenet, Lubeck, Germany4 aut |
700 | 1 | a Lind, L.4 aut |
700 | 1 | a Lindgren, C.u Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England4 aut |
700 | 1 | a Liu, Y. M.u Wake Forest Sch Med, Dept Epidemiol & Prevent, Winston Salem, NC USA4 aut |
700 | 1 | a Livshits, G.u Tel Aviv Univ, Dept Anat & Anthropol, Sackler Fac Med, Tel Aviv, Israel;Kings Coll London, Dept Twin Res & Genet Epidemiol, St Thomas Campus, London, England4 aut |
700 | 1 | a Ljunggren, Östenu Uppsala universitet,Endokrinologi och mineralmetabolism4 aut0 (Swepub:uu)osteljun |
700 | 1 | a Loos, R. J. F.u Icahn Sch Med Mt Sinai, Dept Environm Med & Publ Hlth, New York, NY USA;Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA;Icahn Sch Med Mt Sinai, Inst Child Hlth & Dev, New York, NY 10029 USA;Icahn Sch Med Mt Sinai, Genet Obes & Related Traits Program, New York, NY 10029 USA,Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Netherlands Genom Initiat, Leiden, Netherlands;Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut |
700 | 1 | a Lorentzon, Mattias,d 1970u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Centre for Bone and Arthritis Research,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med, Gothenburg, Sweden4 aut0 (Swepub:gu)xlomat |
700 | 1 | a Luan, J.u Icahn Sch Med Mt Sinai, Dept Environm Med & Publ Hlth, New York, NY USA4 aut |
700 | 1 | a Luben, R. N.u Univ Copenhagen, Fac Hlth & Med Sci, Sect Metabol Genet, Novo Nordisk Fdn Ctr Basic Metab Res, Copenhagen, Denmark4 aut |
700 | 1 | a Malkin, I.u Tel Aviv Univ, Dept Anat & Anthropol, Sackler Fac Med, Tel Aviv, Israel4 aut |
700 | 1 | a McGuigan, F. E.u Lund Univ, Dept Clin Sci Malmo, Malmo, Sweden4 aut |
700 | 1 | a Medina-Gomez, C.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut |
700 | 1 | a Meitinger, T.u Tech Univ Munich, Inst Human Genet, MRI, Munich, Germany;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Human Genet, Neuherberg, Germany4 aut |
700 | 1 | a Melhus, Håkanu Uppsala universitet,Klinisk farmakogenomik och osteoporos4 aut0 (Swepub:uu)hakamelh |
700 | 1 | a Mellström, Dan,d 1945u Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med & Clin Nutr, Gothenburg, Sweden,Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Ctr Med Syst Biol & Netherlands Consortium H, Leiden, Netherlands,Vrije Univ Amsterdam Med Ctr, Dept Epidemiol & Biostat, Amsterdam, Netherlands;Vrije Univ Amsterdam Med Ctr, EMGO Inst, Amsterdam, Netherlands4 aut0 (Swepub:gu)xmelda |
700 | 1 | a Michaelsson, K.4 aut |
700 | 1 | a Mitchell, B. D.u Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Program Personalized & Genom Med, Baltimore, MD 21201 USA;Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Dept Med, Baltimore, MD 21201 USA;Vet Adm Med Ctr, Geriatr Res & Educ Clin Ctr, Baltimore, MD 21218 USA4 aut |
700 | 1 | a Morris, A. P.u Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England;Univ Liverpool, Inst Translat Med, Liverpool, Merseyside, England,Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland;Univ Helsinki, Dept Med Genet, Helsinki, Finland;Univ Cent Hosp, Helsinki, Finland,Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany4 aut |
700 | 1 | a Mosekilde, L.u Aarhus Univ Hosp, Endocrinol & Internal Med, Aarhus, Denmark,Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Program Personalized & Genom Med, Baltimore, MD 21201 USA;Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Dept Med, Baltimore, MD 21201 USA;GlaxoSmithKline, Genet, King Of Prussia, PA USA4 aut |
700 | 1 | a Nethander, Maria,d 1980u Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med & Clin Nutr, Gothenburg, Sweden4 aut0 (Swepub:gu)xnetma |
700 | 1 | a Newman, A. B.u Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15260 USA4 aut |
700 | 1 | a O'Connell, J. R.u Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Program Personalized & Genom Med, Baltimore, MD 21201 USA;Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Dept Med, Baltimore, MD 21201 USA4 aut |
700 | 1 | a Oostra, B. A.4 aut |
700 | 1 | a Orwoll, E. S.u Oregon Hlth & Sci Univ, Portland, OR USA4 aut |
700 | 1 | a Palotie, A.4 aut |
700 | 1 | a Peacock, M.4 aut |
700 | 1 | a Perola, M.4 aut |
700 | 1 | a Peters, A.4 aut |
700 | 1 | a Prince, R. L.4 aut |
700 | 1 | a Psaty, B. M.u Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA;Univ Washington, Dept Hlth Serv, Seattle, WA 98195 USA;Kaiser Permanente, Washington Hlth Res Inst, Seattle, WA USA4 aut |
700 | 1 | a Raikkonen, K.u Univ Helsinki, Dept Psychol & Logoped, Helsinki, Finland4 aut |
700 | 1 | a Ralston, S. H.u Harvard Med Sch, Boston, MA 02115 USA;Western Gen Hosp, MRC Inst Genet & Mol Med, Mol Med Ctr, Edinburgh, Midlothian, Scotland4 aut |
700 | 1 | a Ripatti, S.4 aut |
700 | 1 | a Rivadeneira, F.4 aut |
700 | 1 | a Robbins, J. A.4 aut |
700 | 1 | a Rotter, J. I.u Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Los Angeles Biomed Res Inst, Torrance, CA 90509 USA;Harbor UCLA Med Ctr, Dept Pediat, Torrance, CA 90509 USA4 aut |
700 | 1 | a Rudan, I.u Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15260 USA4 aut |
700 | 1 | a Salomaa, V.u Natl Inst Hlth & Welfare, Helsinki, Finland4 aut |
700 | 1 | a Satterfield, S.4 aut |
700 | 1 | a Schipf, S.4 aut |
700 | 1 | a Shin, C. S.u Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul, South Korea4 aut |
700 | 1 | a Smith, A. V.u Iceland Heart Assoc Holtasmari, Kopavogur, Iceland;Univ Iceland, Fac Med, Reykjavik, Iceland4 aut |
700 | 1 | a Smith, S. B.u Duke Univ, Dept Anesthesiol, Ctr Translat Pain Med, Durham, NC USA4 aut |
700 | 1 | a Soranzo, N.u Wellcome Trust Sanger Inst, Wellcome Trust Genome Campus, Hinxton, England4 aut |
700 | 1 | a Spector, T. D.u Kings Coll London, Dept Twin Res & Genet Epidemiol, St Thomas Campus, London, England4 aut |
700 | 1 | a Stancakova, A.4 aut |
700 | 1 | a Stefansson, K.u Univ Iceland, Fac Med, Reykjavik, Iceland;deCODE Genet, Reykjavik, Iceland4 aut |
700 | 1 | a Steinhagen-Thiessen, E.u Harvard Sch Publ Hlth, Mol & Integrat Physiol Sci Program, Boston, MA USA4 aut |
700 | 1 | a Stolk, L.4 aut |
700 | 1 | a Streeten, E. A.4 aut |
700 | 1 | a Styrkarsdottir, U.u deCODE Genet, Reykjavik, Iceland4 aut |
700 | 1 | a Swart, K. M. A.4 aut |
700 | 1 | a Thompson, P.u Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Tucson, AZ USA;SUNY Stony Brook, Dept Pathol, Stony Brook, NY 11794 USA4 aut |
700 | 1 | a Thomson, C. A.4 aut |
700 | 1 | a Thorleifsson, G.u deCODE Genet, Reykjavik, Iceland4 aut |
700 | 1 | a Thorsteinsdottir, U.u Univ Iceland, Fac Med, Reykjavik, Iceland;deCODE Genet, Reykjavik, Iceland4 aut |
700 | 1 | a Tikkanen, E.u Natl Inst Hlth & Welfare, Helsinki, Finland;Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland4 aut |
700 | 1 | a Tranah, G. J.4 aut |
700 | 1 | a Uitterlinden, A. G.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Netherlands Genom Initiat, Leiden, Netherlands;Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut |
700 | 1 | a van Duijn, C. M.4 aut |
700 | 1 | a van Schoor, N. M.4 aut |
700 | 1 | a Vandenput, L.u Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med & Clin Nutr, Gothenburg, Sweden4 aut |
700 | 1 | a Vollenweider, P.u Lausanne Univ Hosp, Dept Med Internal Med, Lausanne, Switzerland;Fac Biol & Med, Lausanne, Switzerland4 aut |
700 | 1 | a Volzke, H.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands4 aut |
700 | 1 | a Wactawski-Wende, J.u Univ Buffalo SUNY, Dept Epidemiol & Environm Hlth, Buffalo, NY USA4 aut |
700 | 1 | a Walker, M.u Newcastle Univ, Med Sch, Inst Cellular Med Diabetes, Framlington Pl, Newcastle Upon Tyne, Tyne & Wear, England4 aut |
700 | 1 | a Wareham, N. J.u Univ Cambridge, MRC Epidemiol Unit, Sch Clin Med, Cambridge Biomed Campus, Cambridge, England4 aut |
700 | 1 | a Waterworth, D.u GlaxoSmithKline, Genet, King Of Prussia, PA USA4 aut |
700 | 1 | a Weedon, M. N.u Univ Exeter, Med Sch, Royal Devon & Exeter Hosp, Genet Complex Traits, Exeter, Devon, England4 aut |
700 | 1 | a Wichmann, H. E.u Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany;Ludwig Maximilians Univ Munchen, Inst Med Informat Biometry & Epidemiol, Neuherberg, Germany;Tech Univ, Inst Med Stat & Epidemiol, Munich, Germany4 aut |
700 | 1 | a Widen, E.4 aut |
700 | 1 | a Williams, F. M. K.4 aut |
700 | 1 | a Wilson, J. F.u Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Ctr Global Hlth Res, Teviot Pl, Edinburgh, Midlothian, Scotland4 aut |
700 | 1 | a Wright, N. C.4 aut |
700 | 1 | a Yerges-Armstrong, L. M.4 aut |
700 | 1 | a Yu, L.u Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA4 aut |
700 | 1 | a Zhang, W. H.u Ealing Hosp NHS Trust, Cardiol, London, England;Imperial Coll Healthcare NHS Trust, London, England4 aut |
700 | 1 | a Zhao, J. H.u Univ Cambridge, MRC Epidemiol Unit, Sch Clin Med, Cambridge Biomed Campus, Cambridge, England4 aut |
700 | 1 | a Zhou, Y. H.u Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA4 aut |
700 | 1 | a Nielson, C. M.u Oregon Hlth & Sci Univ, Portland, OR USA4 aut |
700 | 1 | a Harris, T. B.u NIA, Lab Epidemiol & Populat Sci, Intramural Res Program, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Demissie, S.4 aut |
700 | 1 | a Kiel, D. P.u Hebrew Senior Life Inst Aging Res, Boston, MA USA;Harvard Med Sch, Boston, MA 02115 USA;Harvard Med Sch, Dept Med, Boston, MA 02115 USA4 aut |
700 | 1 | a Ohlsson, Claes,d 1965u University of Gothenburg,Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med & Clin Nutr, Gothenburg, Sweden4 aut0 (Swepub:gu)xohlcl |
710 | 2 | a Hebrew Senior Life Inst Aging Res, Boston, MA USA;Harvard Med Sch, Boston, MA 02115 USA;Bar Ilan Univ, Azrieli Fac Med, Safed, Israelb Harvard University4 org |
773 | 0 | t American Journal of Clinical Nutritiond : Elsevier BVg 109:2, s. 276-287q 109:2<276-287x 0002-9165x 1938-3207 |
856 | 4 | u https://academic.oup.com/ajcn/article-pdf/109/2/276/28887492/nqy272.pdf |
856 | 4 | u http://dx.doi.org/10.1093/ajcn/nqy272y FULLTEXT |
856 | 4 8 | u https://gup.ub.gu.se/publication/280055 |
856 | 4 8 | u https://doi.org/10.1093/ajcn/nqy272 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-380499 |
856 | 4 8 | u https://lup.lub.lu.se/record/88b31e13-d9a4-49a8-a527-d51bd04337b1 |
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