WFRF:(Barosi G.)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03305naa a2200529 4500 | |
| 001 | oai:DiVA.org:uu-24970 | |
| 003 | SwePub | |
| 008 | 070208s2007 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-249702 URI |
| 024 | 7 | a https://doi.org/10.1038/sj.leu.24044732 DOI |
| 040 | a (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Barosi, G.4 aut |
| 245 | 1 0 | a A unified definition of clinical resistance/intolerance to hydroxyurea in essential thrombocythemia :b results of a consensus process by an international working group |
| 264 | c 2006-11-16 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2007 |
| 338 | a print2 rdacarrier | |
| 520 | a A widely accepted definition of resistance or intolerance to hydroxyurea (HU) in patients with essential thrombocythemia (ET) is lacking. An international working group (WG) was convened to develop a consensus formulation of clinically significant criteria for defining resistance/intolerance to HU in ET. To this aim, an analytic hierarchy process (AHP), a multiple-attribute decision-making technique, was used. The steps consisted of selecting the candidate criteria for defining resistance/intolerance; identifying the motivations that could influence the preference of the WG for any individual criterion; comparing the candidate criteria in a pair-wise manner; and grading them according their ability to fulfill the motivations. Every step in the model was derived by questionnaires or group discussion. The WG proposed that the definition of resistance/intolerance should require the fulfillment of at least one of the following criteria: platelet count greater than 600,000/micro l after 3 months of at least 2 g/day of HU (2.5 g/day in patients with a body weight over 80 kg); platelet count greater than 400,000/micro l and WBC less than 2500/micro l or Hb less than 10 g/dl at any dose of HU; presence of leg ulcers or other unacceptable muco-cutaneous manifestations at any dose of HU; HU-related fever. | |
| 653 | a essential thrombocythemia | |
| 653 | a hydroxyurea | |
| 653 | a analytic hierarchy process | |
| 653 | a resistance | |
| 653 | a intolerance | |
| 653 | a MEDICINE | |
| 653 | a MEDICIN | |
| 700 | 1 | a Besses, C.4 aut |
| 700 | 1 | a Birgegård, Gunnar,d 1944-u Uppsala universitet,Institutionen för medicinska vetenskaper,Hematologi4 aut0 (Swepub:uu)gunnarbg |
| 700 | 1 | a Briere, J.4 aut |
| 700 | 1 | a Cervantes, F.4 aut |
| 700 | 1 | a Finazzi, G.4 aut |
| 700 | 1 | a Gisslinger, H.4 aut |
| 700 | 1 | a Griesshammer, M.4 aut |
| 700 | 1 | a Gugliotta, L.4 aut |
| 700 | 1 | a Harrison, C.4 aut |
| 700 | 1 | a Hasselbalch, H.4 aut |
| 700 | 1 | a Lengfelder, E.4 aut |
| 700 | 1 | a Reilly, J. T.4 aut |
| 700 | 1 | a Michiels, J. J.4 aut |
| 700 | 1 | a Barbui, T.4 aut |
| 710 | 2 | a Uppsala universitetb Institutionen för medicinska vetenskaper4 org |
| 773 | 0 | t Leukemiad : Springer Science and Business Media LLCg 21:2, s. 277-280q 21:2<277-280x 0887-6924x 1476-5551 |
| 856 | 4 | u https://www.nature.com/articles/2404473.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-24970 |
| 856 | 4 8 | u https://doi.org/10.1038/sj.leu.2404473 |
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- Barosi, G.
- Besses, C.
- Birgegård, Gunna ...
- Briere, J.
- Cervantes, F.
- Finazzi, G.
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- Gisslinger, H.
- Griesshammer, M.
- Gugliotta, L.
- Harrison, C.
- Hasselbalch, H.
- Lengfelder, E.
- Reilly, J. T.
- Michiels, J. J.
- Barbui, T.
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