Sökning: WFRF:(Bhiladvala P) > A new method to mea...
Fältnamn | Indikatorer | Metadata |
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000 | 02622naa a2200277 4500 | |
001 | oai:lup.lub.lu.se:815b1903-01fc-4d73-ae2e-bf8a7edaeea5 | |
003 | SwePub | |
008 | 160401s2001 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/11214882 URI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Strandberg, K4 aut |
245 | 1 0 | a A new method to measure plasma levels of activated protein C in complex with protein C inhibitor in patients with acute coronary syndromes |
264 | 1 | c 2001 |
520 | a Our newly devised immunofluorometric sandwich assay for measuring plasma concentrations of activated protein C (APC) in complex with protein C inhibitor (PCI) was compared with testing for conventional markers of myocardial damage CKMB (creatine kinase MB), TNI (troponin I) and hypercoagulability (D-dimer, TAT) in 76 patients with suspected myocardial infarction (MI). APC-PCI complex levels in samples drawn on admission did not correlate with CKMB in the simultaneously drawn sample but correlated closely with maximal CKMB, which reflects MI size (r = 0.52). The areas under the receiver operating characteristics (ROC) curves calculated for the APC-PCI complex results obtained upon admission did not differ significantly from the corresponding values for CKMB, TNI or TAT. Our results show that in patients at risk for MI, the APC-PCI concentration is a sensitive and independent marker that can identify a subgroup of MI patients with normal CKMB but an increased APC-PCI level upon admission. It remains to be determined whether these patients would benefit from early intensive anticoagulant treatment. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng |
700 | 1 | a Bhiladvala, P4 aut |
700 | 1 | a Holm, Johanu Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine4 aut0 (Swepub:lu)medf-jho |
700 | 1 | a Stenflo, Johanu Lund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)klke-jst |
710 | 2 | a Institutionen för kliniska vetenskaper, Malmöb Medicinska fakulteten4 org |
773 | 0 | t Blood Coagulation and Fibrinolysisg 12:7, s. 503-510q 12:7<503-510x 1473-5733 |
856 | 4 8 | u https://lup.lub.lu.se/record/1121488 |
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