Sökning: WFRF:(Chen Xiaoqing) > Breast cancer risk ...
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000 | 15768naa a2202077 4500 | |
001 | oai:DiVA.org:umu-60144 | |
003 | SwePub | |
008 | 121002s2012 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:ba0e7816-d120-48a7-8df2-0edece3a8a76 | |
009 | oai:prod.swepub.kib.ki.se:124891753 | |
009 | oai:DiVA.org:liu-79692 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-601442 URI |
024 | 7 | a https://doi.org/10.1371/journal.pone.00357062 DOI |
024 | 7 | a https://lup.lub.lu.se/record/30015462 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1248917532 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-796922 URI |
040 | a (SwePub)umud (SwePub)lud (SwePub)kid (SwePub)liu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Kirchhoff, Tomasu Mem Sloan Kettering Cancer Centre, USA4 aut |
245 | 1 0 | a Breast cancer risk and 6q22.33 :b combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2 |
264 | c 2012-06-29 | |
264 | 1 | b Public library of science,c 2012 |
338 | a electronic2 rdacarrier | |
520 | a Recently, a locus on chromosome 6q22.33 (rs2180341) was reported to be associated with increased breast cancer risk in the Ashkenazi Jewish (AJ) population, and this association was also observed in populations of non-AJ European ancestry. In the present study, we performed a large replication analysis of rs2180341 using data from 31,428 invasive breast cancer cases and 34,700 controls collected from 25 studies in the Breast Cancer Association Consortium (BCAC). In addition, we evaluated whether rs2180341 modifies breast cancer risk in 3,361 BRCA1 and 2,020 BRCA2 carriers from 11 centers in the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). Based on the BCAC data from women of European ancestry, we found evidence for a weak association with breast cancer risk for rs2180341 (per-allele odds ratio (OR) = 1.03, 95% CI 1.00-1.06, p = 0.023). There was evidence for heterogeneity in the ORs among studies (I(2) = 49.3%; p = <0.004). In CIMBA, we observed an inverse association with the minor allele of rs2180341 and breast cancer risk in BRCA1 mutation carriers (per-allele OR = 0.89, 95%CI 0.80-1.00, p = 0.048), indicating a potential protective effect of this allele. These data suggest that that 6q22.33 confers a weak effect on breast cancer risk. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a genome-wide association | |
653 | a susceptibility loci | |
653 | a variants | |
653 | a alleles | |
653 | a FGFR2 | |
653 | a gene | |
653 | a MEDICINE | |
700 | 1 | a Gaudet, Mia Mu Mem Sloan Kettering Cancer Centre, USA,University of Medical Centre Utrecht, Netherlands4 aut |
700 | 1 | a Antoniou, Antonis Cu University of Cambridge, England,University of Pisa, Italy Pisa University Hospital, Italy,Yorkshire Regional Genet Serv, England4 aut |
700 | 1 | a McGuffog, Lesleyu University of Cambridge, England4 aut |
700 | 1 | a Humphreys, Manjeet Ku University of Cambridge, England4 aut |
700 | 1 | a Dunning, Alison Mu University of Cambridge, England4 aut |
700 | 1 | a Bojesen, Stig Eu University of Copenhagen, Denmark4 aut |
700 | 1 | a Nordestgaard, Børge Gu University of Copenhagen, Denmark University of Copenhagen, Denmark4 aut |
700 | 1 | a Flyger, Henriku University of Copenhagen, Denmark4 aut |
700 | 1 | a Kang, Daeheeu Seoul National University, South Korea National Cancer Centre, South Korea University of Ulsan, South Korea4 aut |
700 | 1 | a Yoo, Keun-Youngu Seoul National University, South Korea National Cancer Centre, South Korea University of Ulsan, South Korea4 aut |
700 | 1 | a Noh, Dong-Youngu Seoul National University, South Korea National Cancer Centre, South Korea University of Ulsan, South Korea4 aut |
700 | 1 | a Ahn, Sei-Hyunu Seoul National University, South Korea National Cancer Centre, South Korea University of Ulsan, South Korea4 aut |
700 | 1 | a Dork, Thilou Hannover Medical Sch, Germany Hannover Medical Sch, Germany4 aut |
700 | 1 | a Schürmann, Peteru Hannover Medical Sch, Germany Hannover Medical Sch, Germany4 aut |
700 | 1 | a Karstens, Johann Hu Hannover Medical Sch, Germany Hannover Medical Sch, Germany,Queensland Institute Medical Research, Australia Peter MacCallum Cancer Centre, Australia4 aut |
700 | 1 | a Hillemanns, Peteru Hannover Medical Sch, Germany Hannover Medical Sch, Germany4 aut |
700 | 1 | a Couch, Fergus Ju Mayo Clin, MN USA Mayo Clin, MN USA4 aut |
700 | 1 | a Olson, Janetu Mayo Clin, MN USA4 aut |
700 | 1 | a Vachon, Celineu Mayo Clin, MN USA4 aut |
700 | 1 | a Wang, Xianshuu Mayo Clin, MN USA4 aut |
700 | 1 | a Cox, Angelau University of Sheffield, England4 aut |
700 | 1 | a Brock, Ianu University of Sheffield, England4 aut |
700 | 1 | a Elliott, Graemeu University of Sheffield, England4 aut |
700 | 1 | a Reed, Malcolm W Ru University of Sheffield, England4 aut |
700 | 1 | a Burwinkel, Barbarau German Cancer Research Centre, Germany,Queensland Institute Medical Research, Australia Peter MacCallum Cancer Centre, Australia,Netherlands Cancer Institute, Netherlands,University Hospital Maastricht, Netherlands4 aut |
700 | 1 | a Meindl, Alfonsu Technical University of Munich, Germany,Leiden University, Netherlands4 aut |
700 | 1 | a Brauch, Hiltrudu Dr Margarete Fischer Bosch Institute Clin Pharmacol, Germany University of Tubingen, Germany University of Tubingen, Germany4 aut |
700 | 1 | a Hamann, Uteu Deutsch Krebsforschungszentrum, Germany4 aut |
700 | 1 | a Ko, Yon-Dschunu Evangel Kliniken Bonn gGmbH, Germany4 aut |
700 | 1 | a Broeks, Annegienu Netherlands Cancer Institute, Netherlands Netherlands Cancer Institute, Netherlands Netherlands Cancer Institute, Netherlands4 aut |
700 | 1 | a Schmidt, Marjanka Ku Netherlands Cancer Institute, Netherlands Netherlands Cancer Institute, Netherlands Netherlands Cancer Institute, Netherlands4 aut |
700 | 1 | a Van 't Veer, Laura Ju Netherlands Cancer Institute, Netherlands Netherlands Cancer Institute, Netherlands Netherlands Cancer Institute, Netherlands4 aut |
700 | 1 | a Braaf, Linde Mu Netherlands Cancer Institute, Netherlands Netherlands Cancer Institute, Netherlands Netherlands Cancer Institute, Netherlands4 aut |
700 | 1 | a Johnson, Nicholau Institute Cancer Research, England4 aut |
700 | 1 | a Fletcher, Oliviau Institute Cancer Research, England4 aut |
700 | 1 | a Gibson, Lornau London School Hyg and Trop Med, England4 aut |
700 | 1 | a Peto, Julianu London School Hyg and Trop Med, England,Vrije University, Netherlands4 aut |
700 | 1 | a Turnbull, Clareu Institute Cancer Research, England,University of Cambridge, England4 aut |
700 | 1 | a Seal, Sheilau Karolinska Institutet,Institute Cancer Research, England4 aut |
700 | 1 | a Renwick, Anthonyu Institute Cancer Research, England4 aut |
700 | 1 | a Rahman, Nazneenu Institute Cancer Research, England4 aut |
700 | 1 | a Wu, Pei-Eiu Academic Sinica, Taiwan4 aut |
700 | 1 | a Yu, Jyh-Cherngu Tri Serv Gen Hospital, Taiwan4 aut |
700 | 1 | a Hsiung, Chia-Niu Academic Sinica, Taiwan4 aut |
700 | 1 | a Shen, Chen-Yangu Academic Sinica, Taiwan4 aut |
700 | 1 | a Southey, Melissa Cu University of Melbourne, Australia Cancer Council, Australia University of Melbourne, Australia4 aut |
700 | 1 | a Hopper, John Lu University of Melbourne, Australia4 aut |
700 | 1 | a Hammet, Fleuru University of Melbourne, Australia4 aut |
700 | 1 | a Van Dorpe, Thijsu Katholieke University of Leuven, Belgium4 aut |
700 | 1 | a Dieudonne, Anne-Sophieu Katholieke University of Leuven, Belgium4 aut |
700 | 1 | a Hatse, Sigridu Katholieke University of Leuven, Belgium4 aut |
700 | 1 | a Lambrechts, Dietheru Vesalius Research Centre, Belgium4 aut |
700 | 1 | a Andrulis, Irene Lu Karolinska Institutet,Cancer Care Ontario, Canada Mt Sinai Hospital, Canada University of Toronto, Canada4 aut |
700 | 1 | a Bogdanova, Nataliau NN Alexandrov Research Institute Oncology and Medical Radiol, Byelarus4 aut |
700 | 1 | a Antonenkova, Nataliau NN Alexandrov Research Institute Oncology and Medical Radiol, Byelarus4 aut |
700 | 1 | a Rogov, Juri Iu NN Alexandrov Research Institute Oncology and Medical Radiol, Byelarus4 aut |
700 | 1 | a Prokofieva, Dariau Russian Academic Science, Russia,University of Cambridge, England University of Cambridge, England4 aut |
700 | 1 | a Bermisheva, Marinau Russian Academic Science, Russia4 aut |
700 | 1 | a Khusnutdinova, Elzau Russian Academic Science, Russia4 aut |
700 | 1 | a van Asperen, Christi Ju Leiden University, Netherlands4 aut |
700 | 1 | a Tollenaar, Robert A E Mu University of Eastern Finland, Finland Kuopio University Hospital, Finland4 aut |
700 | 1 | a Hooning, Maartje Ju Erasmus MC, Netherlands4 aut |
700 | 1 | a Devilee, Peteru Leiden University, Netherlands4 aut |
700 | 1 | a Margolin, Sarau Karolinska Institute, Sweden Karolinska University, Sweden4 aut |
700 | 1 | a Lindblom, Annikau Karolinska Institute, Sweden4 aut |
700 | 1 | a Milne, Roger Lu Spanish National Cancer Centre, Spain4 aut |
700 | 1 | a Arias, José Ignaciou Monte Naranco Hospital, Spain4 aut |
700 | 1 | a Zamora, M Pilaru La Paz University Hospital, Spain4 aut |
700 | 1 | a Benítez, Javieru Spanish National Cancer Centre, Spain Centre Invest Biomed Red Enfermedades Rares, Spain4 aut |
700 | 1 | a Severi, Gianlucau Cancer Council, Australia University of Melbourne, Australia4 aut |
700 | 1 | a Baglietto, Laurau Cancer Council, Australia University of Melbourne, Australia4 aut |
700 | 1 | a Giles, Graham Gu Cancer Council, Australia University of Melbourne, Australia4 aut |
700 | 1 | a Spurdle, Amanda B4 aut |
700 | 1 | a Beesley, Jonathanu Queensland Institute Medical Research, Australia Peter MacCallum Cancer Centre, Australia4 aut |
700 | 1 | a Chen, Xiaoqingu Queensland Institute Medical Research, Australia Peter MacCallum Cancer Centre, Australia4 aut |
700 | 1 | a Holland, Helene4 aut |
700 | 1 | a Healey, Sueu Queensland Institute Medical Research, Australia Peter MacCallum Cancer Centre, Australia4 aut |
700 | 1 | a Wang-Gohrke, Shanu University of Ulm, Germany4 aut |
700 | 1 | a Chang-Claude, Jennyu German Cancer Research Centre DFKZ, Germany4 aut |
700 | 1 | a Mannermaa, Arto4 aut |
700 | 1 | a Kosma, Veli-Mattiu University of Eastern Finland, Finland Kuopio University Hospital, Finland4 aut |
700 | 1 | a Kauppinen, Jaanau University of Eastern Finland, Finland Kuopio University Hospital, Finland4 aut |
700 | 1 | a Kataja, Vesau Vaasa Central Hospital, Finland Kuopio University Hospital, Finland4 aut |
700 | 1 | a Agnarsson, Bjarni Au Landspitali University Hospital, Iceland University of Iceland, Iceland4 aut |
700 | 1 | a Caligo, Maria A4 aut |
700 | 1 | a Godwin, Andrew Ku Fox Chase Cancer Centre, PA 19111 USA4 aut |
700 | 1 | a Nevanlinna, Heliu University of Helsinki, Finland4 aut |
700 | 1 | a Heikkinen, Tuomasu University of Helsinki, Finland4 aut |
700 | 1 | a Fredericksen, Zacharyu Mayo Clin, MN USA4 aut |
700 | 1 | a Lindor, Noralaneu Mayo Clin, MN USA4 aut |
700 | 1 | a Nathanson, Katherine Lu University of Penn, PA 19104 USA University of Penn, PA 19104 USA4 aut |
700 | 1 | a Domchek, Susan Mu University of Penn, PA 19104 USA University of Penn, PA 19104 USA4 aut |
700 | 1 | a Loman, Niklasu Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,University of Lund Hospital, Sweden4 aut0 (Swepub:lu)onk-nlo |
700 | 1 | a Karlsson, Peru Sahlgrens University Hospital, Sweden4 aut |
700 | 1 | a Stenmark Askmalm, Marieu Östergötlands Läns Landsting,Linköpings universitet,Onkologi,Hälsouniversitetet,Klinisk patologi och klinisk genetik4 aut0 (Swepub:liu)marst93 |
700 | 1 | a Melin, Beatriceu Umeå universitet,Onkologi,Umeå University, Sweden4 aut0 (Swepub:umu)bema0010 |
700 | 1 | a von Wachenfeldt, Annau Karolinska University Hospital, Sweden4 aut |
700 | 1 | a Hogervorst, Frans B L4 aut |
700 | 1 | a Verheus, Martijnu Netherlands Cancer Institute, Netherlands4 aut |
700 | 1 | a Rookus, Matti Au Netherlands Cancer Institute, Netherlands4 aut |
700 | 1 | a Seynaeve, Carolineu Erasmus MC, Netherlands4 aut |
700 | 1 | a Oldenburg, Rogier Au Erasmus MC, Netherlands4 aut |
700 | 1 | a Ligtenberg, Marjolijn Ju Radboud University of Nijmegen, Netherlands4 aut |
700 | 1 | a Ausems, Margreet G E M4 aut |
700 | 1 | a Aalfs, Cora Mu Amsterdam Medical Centre, Netherlands4 aut |
700 | 1 | a Gille, Hans J P4 aut |
700 | 1 | a Wijnen, Juul Tu Vrije University, Netherlands4 aut |
700 | 1 | a Gómez García, Encarna B4 aut |
700 | 1 | a Peock, Susanu University of Cambridge, England4 aut |
700 | 1 | a Cook, Margaretu University of Cambridge, England4 aut |
700 | 1 | a Oliver, Clare T4 aut |
700 | 1 | a Frost, Debrau University of Cambridge, England4 aut |
700 | 1 | a Luccarini, Craigu University of Cambridge, England4 aut |
700 | 1 | a Pichert, Gabriellau Guys and St Thomas NHS Fdn Trust, England4 aut |
700 | 1 | a Davidson, Rosemarieu Yorkhill Hospital, Scotland4 aut |
700 | 1 | a Chu, Carol4 aut |
700 | 1 | a Eccles, Dianau Princess Anne Hospital, England4 aut |
700 | 1 | a Ong, Kai-Renu Birmingham Womens Hospital Healthcare NHS Trust, England4 aut |
700 | 1 | a Cook, Jackieu Sheffield Childrens Hospital, England4 aut |
700 | 1 | a Douglas, Fionau Newcastle Tyne Hospital NHS Trust, England,University of Cambridge, England University of Cambridge, England4 aut |
700 | 1 | a Hodgson, Shirleyu University of London, England4 aut |
700 | 1 | a Evans, D Garethu Central Manchester University Hospital National Health Serv NHS Fdn, England4 aut |
700 | 1 | a Eeles, Rosalindu Institute Cancer Research, England Royal Marsden NHS Fdn Trust, England4 aut |
700 | 1 | a Gold, Bertu NCI, MD USA4 aut |
700 | 1 | a Pharoah, Paul D P4 aut |
700 | 1 | a Offit, Kennethu Mem Sloan Kettering Cancer Centre, NY 10021 USA4 aut |
700 | 1 | a Chenevix-Trench, Georgiau Queensland Institute Medical Research, Australia Peter MacCallum Cancer Centre, Australia4 aut |
700 | 1 | a Easton, Douglas F4 aut |
710 | 2 | a Mem Sloan Kettering Cancer Centre, USAb University of Medical Centre Utrecht, Netherlands4 org |
773 | 0 | t PLOS ONEd : Public library of scienceg 7:6q 7:6x 1932-6203 |
856 | 4 | u https://umu.diva-portal.org/smash/get/diva2:558164/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0035706&type=printable |
856 | 4 | u https://portal.research.lu.se/files/4176333/3127254.pdfx primaryx freey FULLTEXT |
856 | 4 | u http://dx.doi.org/10.1371/journal.pone.0035706x freey FULLTEXT |
856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:544120/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-60144 |
856 | 4 8 | u https://doi.org/10.1371/journal.pone.0035706 |
856 | 4 8 | u https://lup.lub.lu.se/record/3001546 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:124891753 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-79692 |
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