WFRF:(Chen Yuning)
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Cancer-fighting potentials of algal polysaccharides as nutraceuticals
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- Ouyang, Yuezhen (författare)
- Engn Res Ctr Fujian Taiwan Special Marine Food Pr, Minist Educ, Fuzhou, Fujian, Peoples R China.;Fujian Agr & Forestry Univ, Coll Food Sci, Fuzhou 350002, Fujian, Peoples R China.
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- Qiu, Yinghui (författare)
- Engn Res Ctr Fujian Taiwan Special Marine Food Pr, Minist Educ, Fuzhou, Fujian, Peoples R China.;Fujian Agr & Forestry Univ, Coll Food Sci, Fuzhou 350002, Fujian, Peoples R China.
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- Liu, Yuning (författare)
- Engn Res Ctr Fujian Taiwan Special Marine Food Pr, Minist Educ, Fuzhou, Fujian, Peoples R China.;Fujian Agr & Forestry Univ, Coll Food Sci, Fuzhou 350002, Fujian, Peoples R China.
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- Engn Res Ctr Fujian Taiwan Special Marine Food Pr, Minist Educ, Fuzhou, Fujian, Peoples R China;Fujian Agr & Forestry Univ, Coll Food Sci, Fuzhou 350002, Fujian, Peoples R China. Zhejiang Univ Sci & Technol, Sch Biol & Chem Engn, Hangzhou 310023, Zhejiang, Peoples R China. (creator_code:org_t)
- Elsevier, 2021
- 2021
- Engelska.
- Ingår i: Food Research International. - : Elsevier. - 0963-9969 .- 1873-7145. ; 147
- Tidskriftsartikel (refereegranskat)
Abstract
Ämnesord
Stäng
- Cancer has been listed as one of the world's five incurable diseases by the World Health Organization and causes tens of thousands of deaths every year. Unfortunately, anticancer agents either show limited efficacy or show serious side effects. The algae possess high nutritional value and their polysaccharides have a variety of biological activities, especially anti-cancer and immunomodulatory properties. Algal polysaccharides exert anticancer effects by inducing apoptosis, cell cycle arrest, anti-angiogenesis, and regulating intestinal flora and immune function. Algal polysaccharides can be combined with nanoparticles and other drugs to reduce the side effects caused by chemotherapy and increase the anticancer effects. This review shows the signal pathways related to the anti-cancer mechanisms of algal polysaccharides, including their influence on intestinal flora and immune regulation, the application of nanoparticles, and the effects on combination therapy and clinical trials of cancer treatments.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Algal polysaccharides
- Anti-cancer
- Gut microbiota: Immune regulation
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- ref (ämneskategori)
- art (ämneskategori)
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- Ouyang, Yuezhen
- Qiu, Yinghui
- Liu, Yuning
- Zhu, Ruiyu
- Chen, Yihan
- El-Seedi, Hesham
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- Chen, Xinhua
- Zhao, Chao
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