WFRF:(Ensworth S)
Sökning: WFRF:(Ensworth S) > Mortality in system...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04579naa a2200685 4500 | |
| 001 | oai:lup.lub.lu.se:497f455d-dab2-496d-903a-2d4623804cdb | |
| 003 | SwePub | |
| 008 | 160401s2006 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/3985272 URI |
| 024 | 7 | a https://doi.org/10.1002/art.219552 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Bernatsky, S.4 aut |
| 245 | 1 0 | a Mortality in systemic lupus erythematosus |
| 264 | c 2006 | |
| 264 | 1 | b Wiley,c 2006 |
| 520 | a Objective. To examine mortality rates in the largest systemic lupus erythematosus (SLE) cohort ever assembled. Methods. Our sample was a multisite international SLE cohort (23 centers, 9,547 patients). Deaths were ascertained by vital statistics registry linkage. Standardized mortality ratio (SMR; ratio of deaths observed to deaths expected) estimates were calculated for-all deaths and by cause. The effects of sex, age, SLE duration, race, and calendar-year periods were determined. Results. The overall SMR was 2.4 (95% confidence interval 2.3-2.5). Particularly high mortality was seen for circulatory disease, infections, renal disease, non-Hodgkin's lymphoma, and lung cancer. The highest SMR estimates were seen in patient groups characterized by female sex, younger age, SLE duration < 1 year, or black/African American race. There was a dramatic decrease in total SMR estimates across calendar-year periods, which was demonstrable for specific causes including death due to infections and death due to renal disorders. However, the SMR due to circulatory diseases tended to increase slightly from the 1970s to the year 2001. Conclusion. Our data from a very large multicenter international cohort emphasize what has been demonstrated previously in smaller samples. These results highlight the increased mortality rate in SLE patients compared with the general population, and they suggest particular risk associated with female sex, younger age, shorter SLE duration, and black/African American race. The risk for certain types of deaths, primarily related to lupus activity (such as renal disease), has decreased over time, while the risk for deaths due to circulatory disease does not appear to have diminished. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng |
| 700 | 1 | a Boivin, J. -F.4 aut |
| 700 | 1 | a Joseph, L.4 aut |
| 700 | 1 | a Manzi, S.4 aut |
| 700 | 1 | a Ginzler, E.4 aut |
| 700 | 1 | a Gladman, D. D.4 aut |
| 700 | 1 | a Urowitz, M.4 aut |
| 700 | 1 | a Fortin, P. R.4 aut |
| 700 | 1 | a Petri, M.4 aut |
| 700 | 1 | a Barr, S.4 aut |
| 700 | 1 | a Gordon, C.4 aut |
| 700 | 1 | a Bae, S. -C.4 aut |
| 700 | 1 | a Isenberg, D.4 aut |
| 700 | 1 | a Zoma, A.4 aut |
| 700 | 1 | a Aranow, C.4 aut |
| 700 | 1 | a Dooley, M. -A.4 aut |
| 700 | 1 | a Nived, Olau Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-oni |
| 700 | 1 | a Sturfelt, Gunnaru Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-gst |
| 700 | 1 | a Steinsson, K.4 aut |
| 700 | 1 | a Alarcon, G.4 aut |
| 700 | 1 | a Senecal, J. -L.4 aut |
| 700 | 1 | a Zummer, M.4 aut |
| 700 | 1 | a Hanly, J.4 aut |
| 700 | 1 | a Ensworth, S.4 aut |
| 700 | 1 | a Pope, J.4 aut |
| 700 | 1 | a Edworthy, S.4 aut |
| 700 | 1 | a Rahman, A.4 aut |
| 700 | 1 | a Sibley, J.4 aut |
| 700 | 1 | a El-Gabalawy, H.4 aut |
| 700 | 1 | a McCarthy, T.4 aut |
| 700 | 1 | a Pierre, Y. St.4 aut |
| 700 | 1 | a Clarke, A.4 aut |
| 700 | 1 | a Ramsey-Goldman, R.4 aut |
| 710 | 2 | a Reumatologi och molekylär skelettbiologib Sektion III4 org |
| 773 | 0 | t Arthritis and Rheumatismd : Wileyg 54:8, s. 2550-2557q 54:8<2550-2557x 1529-0131x 0004-3591 |
| 856 | 4 | u http://dx.doi.org/10.1002/art.21955y FULLTEXT |
| 856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/art.21955 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/398527 |
| 856 | 4 8 | u https://doi.org/10.1002/art.21955 |
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- Bernatsky, S.
- Boivin, J. -F.
- Joseph, L.
- Manzi, S.
- Ginzler, E.
- Gladman, D. D.
- visa fler...
- Urowitz, M.
- Fortin, P. R.
- Petri, M.
- Barr, S.
- Gordon, C.
- Bae, S. -C.
- Isenberg, D.
- Zoma, A.
- Aranow, C.
- Dooley, M. -A.
- Nived, Ola
- Sturfelt, Gunnar
- Steinsson, K.
- Alarcon, G.
- Senecal, J. -L.
- Zummer, M.
- Hanly, J.
- Ensworth, S.
- Pope, J.
- Edworthy, S.
- Rahman, A.
- Sibley, J.
- El-Gabalawy, H.
- McCarthy, T.
- Pierre, Y. St.
- Clarke, A.
- Ramsey-Goldman, ...
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