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The Swedish Maligna...
The Swedish Malignant Middle cerebral artery Infarction Study : long-term results from a prospective study of hemicraniectomy combined with standardized neurointensive care
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- Malm, J. (författare)
- Umeå universitet,Klinisk neurovetenskap
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- Bergenheim, A. T. (författare)
- Umeå universitet,Klinisk neurovetenskap
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- Enblad, P. (författare)
- Department of Neuroscience/Neurosurgery, University Hospital, Uppsala, Sweden
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- Hårdemark, H.-G. (författare)
- Department of Neuroscience/Neurosurgery, University Hospital, Uppsala, Sweden
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- Koskinen, L-O D (författare)
- Umeå universitet,Klinisk neurovetenskap
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- Naredi, Silvana (författare)
- Umeå universitet,Anestesiologi och intensivvård
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- Nordström, Carl-Henrik (författare)
- Lund University,Lunds universitet,Neurokirurgi,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurosurgery,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Norrving, B. (författare)
- Department of Clinical Sciences, Lund, University Hospital, Lund, Sweden
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- Uhlin, J. (författare)
- Umeå universitet,Klinisk neurovetenskap
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- Lindgren, Arne (författare)
- Lund University,Lunds universitet,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
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(creator_code:org_t)
- Copenhagen : Munksgaard, 2006
- 2006
- Engelska.
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Ingår i: Acta Neurologica Scandinavica. - Copenhagen : Munksgaard. - 0001-6314 .- 1600-0404. ; 113:1, s. 25-30
- Relaterad länk:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- Objectives: Hemicraniectomy in patients with malignant middle cerebral artery (mMCA) infarct may be life-saving. The long-term prognosis is unknown.Methods: Patients with mMCA infarct treated with hemicraniectomy between 1998 and 2002 at three hospitals were included. The criterion for surgical intervention was if the patients deteriorated from awake to being responding to painful stimuli only. All patients were followed for at least 1 year. Outcome was defined as alive/dead, walkers/non-walkers or modified Rankin Scale (mRS) score ≤2.Results: Thirty patients were included (median age at stroke onset 49 years, range 17–67 years). Fourteen patients had mMCA infarct on the left side and 16 patients on the right side. Fourteen patients had pupil dilatation before surgery. Hemicraniectomy was performed at a median of 52 h (range 13–235 h) after stroke onset. Nine patients died within 1 month after surgery because of cerebral herniation (n = 6), myocardial infarction (n = 1) or intensive care complications (n = 2). No further deaths occurred during follow-up, which was at median 3.4 years after surgery. Status for the 21 survivors at the last follow-up was: mRS 2 or less (n = 6) and mRS 3–5 (n = 15). The oldest patient with mRS 2 or less was 53 years at stroke onset. Thirteen patients (43%) could walk without substantial aid.Conclusion: The long-term survival after mMCA infarction treated with hemicraniectomy seems to be favourable if the patient survives the acute phase. The outcome as measured with mRS may be better among younger patients.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- Acute Disease
- Adolescent
- Adult
- Aged
- Combined Modality Therapy
- Craniotomy
- Decompression; Surgical
- Disability Evaluation
- Female
- Follow-Up Studies
- Humans
- Infarction; Middle Cerebral Artery/mortality/*surgery/*therapy
- Intensive Care
- Male
- Middle Aged
- Postoperative Care
- Prognosis
- Prospective Studies
- Survival Rate
- Sweden
- Time Factors
- intracranial pressure
- cerebral infarction
- brain oedema
- prognosis
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Malm, J.
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Bergenheim, A. T ...
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Enblad, P.
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Hårdemark, H.-G.
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Koskinen, L-O D
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Naredi, Silvana
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visa fler...
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Nordström, Carl- ...
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Norrving, B.
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Uhlin, J.
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Lindgren, Arne
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