Sökning: WFRF:(Hamilton Erin B.) > (2020) > Variability in the ...
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000 | 27406naa a2202881 4500 | |
001 | oai:DiVA.org:su-182960 | |
003 | SwePub | |
008 | 200708s2020 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:143718314 | |
009 | oai:DiVA.org:liu-166165 | |
009 | oai:hhs.se:1156381660006056 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1829602 URI |
024 | 7 | a https://doi.org/10.1038/s41586-020-2314-92 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1437183142 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1661652 URI |
024 | 7 | a https://research.hhs.se/esploro/outputs/journalArticle/Variability-in-the-analysis-of-a/9910014892977060562 URI |
040 | a (SwePub)sud (SwePub)kid (SwePub)liud (SwePub)hhs | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Botvinik-Nezer, Rotemu Tel Aviv Univ, Israel; Tel Aviv Univ, Israel; Dartmouth Coll, NH 03755 USA,Tel Aviv University4 aut |
245 | 1 0 | a Variability in the analysis of a single neuroimaging dataset by many teams |
264 | c 2020-05-20 | |
264 | 1 | b Springer Science and Business Media LLC,c 2020 |
338 | a print2 rdacarrier | |
500 | a Funding Agencies|Austrian Science FundAustrian Science Fund (FWF) [P29362-G27]; Israel Science FoundationIsrael Science Foundation [ISF 2004/15]; Swedish Foundation for Humanities and Social Sciences [NHS14-1719:1]; National Institutes of Health (NIH)United States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [R24MH117179]; Austrian Science Fund (FWF)Austrian Science Fund (FWF) [SFB F63, P 32686]; Research Foundation Flanders (FWO)FWO; European UnionEuropean Union (EU) [665501]; University of Basel Research Fund; Research Foundation FlandersFWO [12T2517N]; Marie Skodowska-Curie Actions under COFUND [665501]; Obra Social La CaixaLa Caixa Foundation; Vienna Science and Technology Fund [WWTF VRG13-007]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [71801110, 71971199, 71602175, 71942004]; MOE (Ministry of Education in China) Project of Humanities and Social Sciences [18YJC630268]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2018M633270]; Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germanys Excellence Strategy Science of Intelligence (EXC 2002/1)German Research Foundation (DFG) [390523135]; Brain Canada; Health Canada; NIHUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [NIH-NIBIB P41 EB019936, NIH-NIMH R01 MH083320, NIH RF1 MH120021, R01 DA041353]; National Institute Of Mental Health of the NIH [R01MH096906]; Canada First Research Excellence Fund; European Unions Horizon 2020 Research and Innovation Programme [785907]; Max Planck SocietyMax Planck SocietyFoundation CELLEX; Dutch foundation LSH-TKI [LSHM16053-SGF]; NSFNational Science Foundation (NSF) [1631325]; T32 Predoctoral Fellowship from the NIHUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA; Deutsche ForschungsgemeinschaftGerman Research Foundation (DFG) [CRC1193]; Australian National Imaging Facility; National Collaborative Research Infrastructure Strategy (NCRIS) capability; VIDI from the Netherlands Organisation for Scientific Research [452-17-013]; Swedish Research CouncilSwedish Research Council; NIH IRPUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [ZICMH002888, ZICMH002960]; Tianqiao and Chrissy Center for Social and Decision Neuroscience Center Leadership Chair; Belgian Excellence of Science program (EOS) from the FNRS-Belgium [30991544]; EraNET Neuron [R4195]; Ministry of Education of Humanities and Social Science [16YJC630103]; Wellcome TrustWellcome Trust [100309/Z/12/Z] | |
520 | a Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses(1). The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset(2-5). Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed. The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng |
650 | 7 | a SAMHÄLLSVETENSKAPx Psykologi0 (SwePub)5012 hsv//swe |
650 | 7 | a SOCIAL SCIENCESx Psychology0 (SwePub)5012 hsv//eng |
650 | 7 | a NATURVETENSKAPx Biologix Bioinformatik och systembiologi0 (SwePub)106102 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Bioinformatics and Systems Biology0 (SwePub)106102 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi0 (SwePub)303012 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Health Care Service and Management, Health Policy and Services and Health Economy0 (SwePub)303012 hsv//eng |
653 | a Psychology | |
653 | a psykologi | |
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700 | 1 | a Cole, Zachary J.u Univ Nebraska, NE 68588 USA,University of Nebraska–Lincoln4 aut |
700 | 1 | a Collignon, Olivieru Univ Trento, Italy; UCLouvain, Belgium,Université Catholique de Louvain4 aut |
700 | 1 | a Cox, Robert W.u NIMH, MD 20892 USA,National Institutes of Health4 aut |
700 | 1 | a Cunningham, William A.u Univ Toronto, Canada,University of Toronto (Canada, Toronto)4 aut |
700 | 1 | a Czoschke, Stefanu Goethe Univ, Germany,Goethe University Frankfurt (Germany, Frankfurt am Main)4 aut |
700 | 1 | a Dadi, Kamalakeru Imperial Coll London, England; Univ Oxford, England,University of Paris-Saclay (France, Gif-sur-Yvette)4 aut |
700 | 1 | a Davis, Charles P.u Univ Connecticut, CT USA; Univ Connecticut, CT USA; Univ Connecticut, CT USA,Charite, Germany; Charite, Germany; Charite, Germany; Free Univ Berlin, Germany; Humboldt Univ, Germany; Berlin Inst Hlth, Germany; Tech Univ Berlin, Germany; Humboldt Univ, Germany; NeuroMI Milan Ctr Neurosci, Italy,University of Connecticut4 aut |
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700 | 1 | a Eed, Amru CSIC UMH, Spain,Leiden Univ, Netherlands,Spanish National Research Council (Spain, Madrid) - CSIC4 aut |
700 | 1 | a Eickhoff, Simon B.u Heinrich Heine University Düsseldorf4 aut |
700 | 1 | a Erhart, Andrewu Univ Denver, CO 80208 USA,University of Denver4 aut |
700 | 1 | a Fontanesi, Laurau Univ Basel, Switzerland,University of Basel (Switzerland, Basel)4 aut |
700 | 1 | a Fricke, G. Matthewu Univ New Mexico, NM 87131 USA,University of New Mexico (United States, Albuquerque) - UNM4 aut |
700 | 1 | a Fu, Shiguangu Zhejiang Univ Technol, Peoples R China; Zhejiang Univ Technol, Peoples R China,Zhejiang University of Technology (China, Hangzhou) - ZJUT4 aut |
700 | 1 | a Galvan, Adrianau Univ Calif Los Angeles, CA USA,University of California, Los Angeles (United States, Los Angeles) - UCLA4 aut |
700 | 1 | a Gau, Remiu UCLouvain, Belgium,Université Catholique de Louvain4 aut |
700 | 1 | a Genon, Sarahu Res Ctr Julich, Germany; Heinrich Heine Univ Dusseldorf, Germany,Heinrich Heine University Düsseldorf4 aut |
700 | 1 | a Glatard, Tristanu Concordia Univ, Canada,Concordia University (Canada, Montreal)4 aut |
700 | 1 | a Glerean, Enricou Aalto Univ, Finland,Aalto University (Finland, Espoo)4 aut |
700 | 1 | a Goeman, Jelle J.u Leiden Univ, Netherlands,Leiden University (Netherlands, Leiden)4 aut |
700 | 1 | a Golowin, Sergej A. E.u Taipei Medical University4 aut |
700 | 1 | a Gonzalez-Garcia, Carlosu Univ Ghent, Belgium,Ghent University4 aut |
700 | 1 | a Gorgolewski, Krzysztof J.u Stanford Univ, CA 94305 USA,Stanford University4 aut |
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700 | 1 | a Herholz, Peeru McGill Univ, Canada,McGill University (Canada, Montreal)4 aut |
700 | 1 | a Herman, Gabrielleu Ctr Addict and Mental Hlth, Canada,University of Toronto4 aut |
700 | 1 | a Heunis, Stephanu Eindhoven Univ Technol, Netherlands; Epilepsy Ctr Kempenhaeghe, Netherlands,Eindhoven University of Technology (Netherlands, Eindhoven) - TU/e4 aut |
700 | 1 | a Hoffstaedter, Felixu Res Ctr Julich, Germany; Heinrich Heine Univ Dusseldorf, Germany,Heinrich Heine University Düsseldorf (Germany, Düsseldorf) - HHU4 aut |
700 | 1 | a Hogeveen, Jeremyu Univ New Mexico, NM 87131 USA; Univ New Mexico, NM 87131 USA,University of New Mexico4 aut |
700 | 1 | a Holmes, Susanu Stanford Univ, CA 94305 USA,Stanford University4 aut |
700 | 1 | a Hu, Chuan-Pengu LIR, Germany,Leibniz Institute for Neurobiology (Germany, Magdeburg) - LIN4 aut |
700 | 1 | a Huettel, Scott A.u Duke Univ, NC USA,Duke University4 aut |
700 | 1 | a Hughes, Matthew E.u Swinburne Univ Technol, Australia,Swinburne University of Technology (Australia, Melbourne)4 aut |
700 | 1 | a Iacovella, Vittoriou Univ Trento, Italy,University of Trento4 aut |
700 | 1 | a Iordan, Alexandru D.u Univ Michigan, MI USA,University of Michigan–Ann Arbor (United States, Ann Arbor) - UM4 aut |
700 | 1 | a Isager, Peder M.u Eindhoven Univ Technol, Netherlands,Eindhoven University of Technology4 aut |
700 | 1 | a Isik, Ayse I.u Max Planck Inst Empir Aesthet, Germany,Max Planck Society4 aut |
700 | 1 | a Jahn, Andrewu Univ Michigan, MI 48109 USA,University of Michigan–Ann Arbor4 aut |
700 | 1 | a Johnson, Matthew R.4 aut |
700 | 1 | a Johnstone, Tomu Swinburne Univ Technol, Australia,Swinburne University of Technology4 aut |
700 | 1 | a Joseph, Michael J. E.u Ctr Addict and Mental Hlth, Canada4 aut |
700 | 1 | a Juliano, Anthony C.4 aut |
700 | 1 | a Kable, Joseph W.u Univ Penn, PA 19104 USA; Univ Penn, PA 19104 USA,University of Pennsylvania (United States, Philadelphia)4 aut |
700 | 1 | a Kassinopoulos, Michalisu McGill Univ, Canada,McGill University4 aut |
700 | 1 | a Koba, Cemalu IMT Sch Adv Studies Lucca, Italy,IMT School for Advanced Studies Lucca4 aut |
700 | 1 | a Kong, Xiang-Zhenu Max Planck Inst Psycholinguist, Netherlands,Zhejiang Univ Technol, Peoples R China; Zhejiang Univ Technol, Peoples R China,Max Planck Institute for Psycholinguistics4 aut |
700 | 1 | a Koscik, Timothy R.u Univ Iowa, IA 52242 USA4 aut |
700 | 1 | a Kucukboyaci, Nuri Erkutu Univ Nebraska, NE USA; Rutgers New Jersey Med Sch, NJ USA4 aut |
700 | 1 | a Kuhl, Brice A.u Univ Oregon, OR 97403 USA4 aut |
700 | 1 | a Kupek, Sebastianu Univ Innsbruck, Austria4 aut |
700 | 1 | a Laird, Angela R.u Florida Int Univ, FL 33199 USA4 aut |
700 | 1 | a Lamm, Clausu Univ Vienna, Austria; Univ Vienna, Austria4 aut |
700 | 1 | a Langner, Robertu Res Ctr Julich, Germany; Heinrich Heine Univ Dusseldorf, Germany4 aut |
700 | 1 | a Lauharatanahirun, Ninau US CCDC Army Res Lab, MD USA; Univ Penn, PA 19104 USA4 aut |
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700 | 1 | a Lee, Sangilu Univ Penn, PA 19104 USA,Duke Univ, NC USA; LIR, Germany; Johannes Gutenberg Univ Mainz, Germany4 aut |
700 | 1 | a Leemans, Alexanderu Univ Med Ctr Utrecht, Netherlands4 aut |
700 | 1 | a Leo, Andreau IMT Sch Adv Studies Lucca, Italy4 aut |
700 | 1 | a Lesage, Eliseu Univ Ghent, Belgium4 aut |
700 | 1 | a Li, Florau Fralin Biomed Res Inst, VA USA; Nanjing Audit Univ, Peoples R China4 aut |
700 | 1 | a Li, Monica Y. C.u Univ Connecticut, CT USA; Univ Connecticut, CT USA; Univ Connecticut, CT USA; Haskins Labs Inc, CT USA4 aut |
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700 | 1 | a Losecaat Vermeer, Annabel B.4 aut |
700 | 1 | a Love, Bradley C.4 aut |
700 | 1 | a Mack, Michael L.u Univ Toronto, Canada4 aut |
700 | 1 | a Malpica, Norbertou Univ Rey Juan Carlos, Spain4 aut |
700 | 1 | a Marins, Theou UCL, England; DOr Inst Res and Educ IDOR, Brazil4 aut |
700 | 1 | a Maumet, Camilleu Univ Rennes, France4 aut |
700 | 1 | a McDonald, Kelseyu Duke Univ, NC USA4 aut |
700 | 1 | a McGuire, Joseph T.u Boston Univ, MA 02215 USA; Boston Univ, MA 02215 USA4 aut |
700 | 1 | a Melero, Helenau Univ Rey Juan Carlos, Spain; CES Cardenal Cisneros, Spain; Northeastern Univ, MA 02115 USA4 aut |
700 | 1 | a Mendez Leal, Adriana S.u Univ Calif Los Angeles, CA USA4 aut |
700 | 1 | a Meyer, Benjaminu LIR, Germany; Johannes Gutenberg Univ Mainz, Germany4 aut |
700 | 1 | a Meyer, Kristin N.u Univ N Carolina, NC 27515 USA4 aut |
700 | 1 | a Mihai, Gladu Max Planck Inst Human Cognit and Brain Sci, Germany; Tech Univ Dresden, Germany4 aut |
700 | 1 | a Mitsis, Georgios D.u McGill Univ, Canada4 aut |
700 | 1 | a Moll, Jorge4 aut |
700 | 1 | a Nielson, Dylan M.u NIMH, MD 20892 USA4 aut |
700 | 1 | a Nilsonne, Gustavu Stockholms universitet,Biologisk psykologi,Karolinska Institutet, Sweden,Karolinska Inst, Sweden; Stockholm Univ, Sweden4 aut0 (Swepub:su)guni6529 |
700 | 1 | a Notter, Michael P.u Univ Hosp Ctr, Switzerland; Univ Lausanne, Switzerland4 aut |
700 | 1 | a Olivetti, Emanueleu Fdn Bruno Kessler, Italy; Univ Trento, Italy4 aut |
700 | 1 | a Onicas, Adrian I.u IMT Sch Adv Studies Lucca, Italy4 aut |
700 | 1 | a Papale, Paolo4 aut |
700 | 1 | a Patil, Kaustubh R.u Res Ctr Julich, Germany; Heinrich Heine Univ Dusseldorf, Germany4 aut |
700 | 1 | a Peelle, Jonathan E.u Washington Univ, MO 63110 USA4 aut |
700 | 1 | a Perez, Alexandreu McGill Univ, Canada4 aut |
700 | 1 | a Pischedda, Doris4 aut |
700 | 1 | a Poline, Jean-Baptisteu McGill Univ, Canada; Univ Calif Berkeley, CA 94720 USA4 aut |
700 | 1 | a Prystauka, Yaninau Univ Connecticut, CT USA; Univ Connecticut, CT USA; Univ Connecticut, CT USA4 aut |
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700 | 1 | a Reuter-Lorenz, Patricia A.4 aut |
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700 | 1 | a Rodriguez-Thompson, Anais M.u Univ N Carolina, NC 27515 USA4 aut |
700 | 1 | a Romyn, Anthonyu Univ Toronto, Canada4 aut |
700 | 1 | a Salo, Tayloru Florida Int Univ, FL 33199 USA4 aut |
700 | 1 | a Samanez-Larkin, Gregory R.u Duke Univ, NC USA; Duke Univ, NC USA4 aut |
700 | 1 | a Sanz-Morales, Emiliou Univ Rey Juan Carlos, Spain4 aut |
700 | 1 | a Schlichting, Margaret L.u Univ Toronto, Canada4 aut |
700 | 1 | a Schultz, Douglas H.u Dartmouth Coll, NH 03755 USA; Univ Nebraska, NE 68588 USA4 aut |
700 | 1 | a Shen, Qiang4 aut |
700 | 1 | a Sheridan, Margaret A.u Alan Turing Inst, England4 aut |
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700 | 1 | a Smith, David V.u Temple Univ, PA 19122 USA4 aut |
700 | 1 | a Sokol-Hessner, Peteru Univ Denver, CO 80208 USA4 aut |
700 | 1 | a Steinkamp, Simon R.u Res Ctr Julich, Germany4 aut |
700 | 1 | a Tashjian, Sarah M.u Univ Calif Los Angeles, CA USA4 aut |
700 | 1 | a Thirion, Bertrandu Univ Paris Saclay, France4 aut |
700 | 1 | a Thorp, John N.u Columbia Univ, NY 10027 USA4 aut |
700 | 1 | a Tinghög, Gustav,d 1979-u Linköpings universitet,Nationalekonomi,Filosofiska fakulteten,Avdelningen för samhälle och hälsa,Medicinska fakulteten4 aut0 (Swepub:liu)gusti22 |
700 | 1 | a Tisdall, Loreenu Stanford Univ, CA 94305 USA; Univ Basel, Switzerland4 aut |
700 | 1 | a Tompson, Steven H.u US CCDC Army Res Lab, MD USA4 aut |
700 | 1 | a Toro-Serey, Claudiou Boston Univ, MA 02215 USA; Boston Univ, MA 02215 USA4 aut |
700 | 1 | a Torre Tresols, Juan Jesusu Univ Paris Saclay, France4 aut |
700 | 1 | a Tozzi, Leonardou Stanford Univ, CA 94305 USA4 aut |
700 | 1 | a Truong, Vuongu Taipei Med Univ, Taiwan; TMU ShuangHo Hosp, Taiwan4 aut |
700 | 1 | a Turella, Lucau Univ Trento, Italy4 aut |
700 | 1 | a van 't Veer, Anna E.u Leiden Univ, Netherlands4 aut |
700 | 1 | a Verguts, Tomu Univ Ghent, Belgium4 aut |
700 | 1 | a Vettel, Jean M.u US Combat Capabil Dev Command Army Res Lab, MD USA; Univ Calif Santa Barbara, CA 93106 USA; Univ Penn, PA 19104 USA4 aut |
700 | 1 | a Vijayarajah, Saganau Univ Toronto, Canada4 aut |
700 | 1 | a Vo, Khoiu Duke Univ, NC USA; Duke Univ, NC USA4 aut |
700 | 1 | a Wall, Matthew B.4 aut |
700 | 1 | a Weeda, Wouter D.u Leiden Univ, Netherlands4 aut |
700 | 1 | a Weis, Susanneu Res Ctr Julich, Germany; Heinrich Heine Univ Dusseldorf, Germany4 aut |
700 | 1 | a White, David J.u Imperial Coll London, England4 aut |
700 | 1 | a Wisniewski, Davidu Univ Ghent, Belgium4 aut |
700 | 1 | a Xifra-Porxas, Albau McGill Univ, Canada4 aut |
700 | 1 | a Yearling, Emily A.u Univ Connecticut, CT USA; Univ Connecticut, CT USA4 aut |
700 | 1 | a Yoon, Sangsuku Univ Dayton, OH 45469 USA4 aut |
700 | 1 | a Yuan, Ruiu Stanford Univ, CA 94305 USA4 aut |
700 | 1 | a Yuen, Kenneth S. L.4 aut |
700 | 1 | a Zhang, Leiu Univ Vienna, Austria4 aut |
700 | 1 | a Zhang, Xuu Univ Connecticut, CT USA; Univ Connecticut, CT USA; Univ Connecticut, CT USA4 aut |
700 | 1 | a Zosky, Joshua E.u Univ Nebraska, NE 68588 USA; Univ Nebraska, NE USA4 aut |
700 | 1 | a Nichols, Thomas E.u Univ Oxford, England4 aut |
700 | 1 | a Poldrack, Russell A.4 aut |
700 | 1 | a Schonberg, Tomu Tel Aviv Univ, Israel; Tel Aviv Univ, Israel4 aut |
710 | 2 | a Tel Aviv Univ, Israel; Tel Aviv Univ, Israel; Dartmouth Coll, NH 03755 USAb Tel Aviv University4 org |
773 | 0 | t Natured : Springer Science and Business Media LLCg 582, s. 84-88q 582<84-88x 0028-0836x 1476-4687 |
856 | 4 | u https://pure.mpg.de/pubman/item/item_3235357_11/component/file_3244335/Botvinik-Nezer_etal_2020_Variability%20in%20the%20analysis%20of%20a%20single....pdf |
856 | 4 | u https://research.hhs.se/esploro/outputs/journalArticle/Variability-in-the-analysis-of-a/991001489297706056x primaryx Object in context |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-182960 |
856 | 4 8 | u https://doi.org/10.1038/s41586-020-2314-9 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:143718314 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-166165 |
856 | 4 8 | u https://research.hhs.se/esploro/outputs/journalArticle/Variability-in-the-analysis-of-a/991001489297706056 |
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