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WFRF:(Johannesdottir Fjola)
 

Sökning: WFRF:(Johannesdottir Fjola) > Mid-Thigh Cortical ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003517naa a2200469 4500
001oai:lup.lub.lu.se:82a70347-6a4f-4917-a2b7-04a3336e4c6c
003SwePub
008160401s2012 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/25630752 URI
0247 a https://doi.org/10.1007/s00223-012-9585-62 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Johannesdottir, Fjola4 aut
2451 0a Mid-Thigh Cortical Bone Structural Parameters, Muscle Mass and Strength, and Association with Lower Limb Fractures in Older Men and Women (AGES-Reykjavik Study)
264 c 2012-03-27
264 1b Springer Science and Business Media LLC,c 2012
520 a In a cross-sectional study we investigated the relationship between muscle and bone parameters in the mid-thigh in older people using data from a single axial computed tomographic section through the mid-thigh. Additionally, we studied the association of these variables with incident low-trauma lower limb fractures. A total of 3,762 older individuals (1,838 men and 1,924 women), aged 66-96 years, participants in the AGES-Reykjavik study, were studied. The total cross-sectional muscular area and knee extensor strength declined with age similarly in both sexes. Muscle parameters correlated most strongly with cortical area and total shaft area (adjusted for age, height, and weight) but explained < 10 % of variability in those bone parameters. The increment in medullary area (MA) and buckling ratio (BR) with age was almost fourfold greater in women than men. The association between MA and muscle parameters was nonsignificant. During a median follow-up of 5.3 years, 113 women and 66 men sustained incident lower limb fractures. Small muscular area, low knee extensor strength, large MA, low cortical thickness, and high BR were significantly associated with fractures in both sexes. Our results show that bone and muscle loss proceed at different rates and with different gender patterns.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Ortopedi0 (SwePub)302112 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Orthopaedics0 (SwePub)302112 hsv//eng
653 a Mid-thigh
653 a Muscle-bone relationship
653 a Aging
653 a Fracture risk
653 a CT
7001 a Aspelund, Thor4 aut
7001 a Siggeirsdottir, Kristin4 aut
7001 a Jonsson, Brynjolfuru Lund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups4 aut0 (Swepub:lu)med-byj
7001 a Mogensen, Brynjolfur4 aut
7001 a Sigurdsson, Sigurdur4 aut
7001 a Harris, Tamara B.4 aut
7001 a Gudnason, Vilmundur G.4 aut
7001 a Lang, Thomas F.4 aut
7001 a Sigurdsson, Gunnar4 aut
7102 a Ortopedi - klinisk och molekylär osteoporosforskningb Forskargrupper vid Lunds universitet4 org
7730 t Calcified Tissue Internationald : Springer Science and Business Media LLCg 90:5, s. 354-364q 90:5<354-364x 1432-0827x 0171-967X
8564 u http://dx.doi.org/10.1007/s00223-012-9585-6y FULLTEXT
8564 u https://europepmc.org/articles/pmc5111551?pdf=render
8564 8u https://lup.lub.lu.se/record/2563075
8564 8u https://doi.org/10.1007/s00223-012-9585-6

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