Sökning: WFRF:(Kanduri Meena) > (2010-2014) > The risk-associated...
Fältnamn | Indikatorer | Metadata |
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000 | 10050naa a2200757 4500 | |
001 | oai:gup.ub.gu.se/206500 | |
003 | SwePub | |
008 | 240528s2014 | |||||||||||000 ||eng| | |
009 | oai:research.chalmers.se:d6db9c06-ceb2-4bd7-a37a-bcdc22c93b8e | |
009 | oai:DiVA.org:uu-238013 | |
009 | oai:prod.swepub.kib.ki.se:130135188 | |
024 | 7 | a https://gup.ub.gu.se/publication/2065002 URI |
024 | 7 | a https://doi.org/10.1016/j.ccell.2014.09.0142 DOI |
024 | 7 | a https://research.chalmers.se/publication/2065002 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2380132 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1301351882 URI |
040 | a (SwePub)gud (SwePub)cthd (SwePub)uud (SwePub)ki | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Pandey, Gaurav Kumaru Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics,University of Gothenburg,Department of Medical Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut |
245 | 1 0 | a The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation. |
264 | 1 | b Elsevier BV,c 2014 |
520 | a Neuroblastoma is an embryonal tumor of the sympathetic nervous system and the most common extracranial tumor of childhood. By sequencing transcriptomes of low- and high-risk neuroblastomas, we detected differentially expressed annotated and nonannotated long noncoding RNAs (lncRNAs). We identified a lncRNA neuroblastoma associated transcript-1 (NBAT-1) as a biomarker significantly predicting clinical outcome of neuroblastoma. CpG methylation and a high-risk neuroblastoma associated SNP on chromosome 6p22 functionally contribute to NBAT-1 differential expression. Loss of NBAT-1 increases cellular proliferation and invasion. It controls these processes via epigenetic silencing of target genes. NBAT-1 loss affects neuronal differentiation through activation of the neuronal-specific transcription factor NRSF/REST. Thus, loss of NBAT-1 contributes to aggressive neuroblastoma by increasing proliferation and impairing differentiation of neuronal precursors. | |
650 | 7 | a NATURVETENSKAPx Biologix Biokemi och molekylärbiologi0 (SwePub)106022 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Biochemistry and Molecular Biology0 (SwePub)106022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a NBAT-1 | |
653 | a NBAT1 | |
653 | a NBAT | |
653 | a Neuroblastoma | |
653 | a long noncoding RNA | |
653 | a Epigenetics | |
653 | a NBAT-1 | |
700 | 1 | a Mitra, Sanhitau Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics,University of Gothenburg,Department of Medical Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xmitsa |
700 | 1 | a Subhash, Santhilal,d 1987u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics,University of Gothenburg,Department of Medical Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xsubsa |
700 | 1 | a Hertwig, Falku Department of Pediatric Hematology and Oncology, University Children’s Hospital of Cologne, and Center for Molecular Medicine Cologne, University of Cologne, Germany4 aut |
700 | 1 | a Kanduri, Meena,d 1974u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine,University of Gothenburg,Department of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xkanme |
700 | 1 | a Mishra, Kankadeb,d 1981u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics,University of Gothenburg,Department of Medical Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xmiska |
700 | 1 | a Fransson, Susanne,d 1975u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics,University of Gothenburg,Department of Clinical Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xfrans |
700 | 1 | a Ganeshram, Abiarchanau Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics,University of Gothenburg,Department of Medical Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut |
700 | 1 | a Mondal, Tanmoy,d 1981u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics,University of Gothenburg,Department of Medical Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xmonta |
700 | 1 | a Bandaru, Sashidaru Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk kemi och cellbiologi,Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology,University of Gothenburg,Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xbands |
700 | 1 | a Östensson, Malin,d 1984u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics,University of Gothenburg,Department of Clinical Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:cth)malino |
700 | 1 | a Akyürek, Levent,d 1966u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk kemi och cellbiologi,Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology,University of Gothenburg,Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xakyle |
700 | 1 | a Abrahamsson, Jonas,d 1954u Department of Pediatrics, The Queen Silvia Children’s Hospital, Sweden4 aut0 (Swepub:gu)xabrjo |
700 | 1 | a Pfeifer, Susan,d 1948-u Uppsala universitet,Pediatrik,Barnonkologisk forskning/Pfeifer4 aut0 (Swepub:uu)susapfei |
700 | 1 | a Larsson, Erik,d 1975u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk kemi och cellbiologi,Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology,University of Gothenburg,Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xlarer |
700 | 1 | a Shi, Lemingu School of Pharmacy, Fudan University, Shanghai, China4 aut |
700 | 1 | a Peng, Zhiyuu BGI-Guangzhou, China4 aut |
700 | 1 | a Fischer, Matthiasu Department of Pediatric Hematology and Oncology, University Children’s Hospital of Cologne, and Center for Molecular Medicine Cologne, University of Cologne, Germany4 aut |
700 | 1 | a Martinsson, Tommy,d 1956u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics,University of Gothenburg,Department of Clinical Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xmarto |
700 | 1 | a Hedborg, Fredrik,d 1950-u Uppsala universitet,Institutionen för kvinnors och barns hälsa,Barnonkologisk forskning/Pfeifer4 aut0 (Swepub:uu)fredhedb |
700 | 1 | a Kogner, Peru Karolinska Institutet4 aut |
700 | 1 | a Kanduri, Chandrasekhar,d 1967u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics,University of Gothenburg,Department of Medical Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xchaka |
710 | 2 | a Göteborgs universitetb Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik4 org |
773 | 0 | t Cancer Celld : Elsevier BVg 26:5, s. 722-737q 26:5<722-737x 1535-6108x 1878-3686 |
856 | 4 | u http://www.cell.com/article/S1535610814003778/pdf |
856 | 4 | u http://dx.doi.org/10.1016/j.ccell.2014.09.014y FULLTEXT |
856 | 4 8 | u https://gup.ub.gu.se/publication/206500 |
856 | 4 8 | u https://doi.org/10.1016/j.ccell.2014.09.014 |
856 | 4 8 | u https://research.chalmers.se/publication/206500 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-238013 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:130135188 |
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