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WFRF:(Karout Bassam)
 

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004445naa a2200469 4500
001oai:DiVA.org:uu-496808
003SwePub
008230222s2023 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4968082 URI
0247 a https://doi.org/10.1080/00365521.2022.21061492 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Ud-din, Moeenu Uppsala universitet,Gastroenterologi/hepatologi4 aut0 (Swepub:uu)moeud574
2451 0a DIgestive COmplications in DIabetes :b the DICODI population study
264 c 2022-08-12
264 1b Taylor & Francis,c 2023
338 a electronic2 rdacarrier
520 a BackgroundDiabetes type 1 and type 2 may develop gastrointestinal complications e.g., gastroparesis and gastroenteropathy. Concomitant celiac disease and pancreatic exocrine insufficiency occur with high prevalence in diabetes and with symptomatic overlap. Consequently, it is a challenge to disentangle symptoms of these conditions and separate them from functional dyspepsia. We aim to develop a clinical decision-support tool to differentiate the underlying disease in a plethora of gastrointestinal symptoms.MethodsAn internet-based computerized survey will collect basic characteristics (diabetes type, age, gender, duration, HbA1c, treatment) and patient reported outcomes by validated questionnaires focusing on (1) gastroparesis using Gastroparesis Cardinal Symptom Index; (2) gastroenteropathy using Gastrointestinal Symptom Rating Scale; (3) celiac disease using Celiac Symptom Index and (4) pancreatic exocrine insufficiency with Pancreatic Exocrine Insufficiency Questionnaire. Logistic regression and multiple regression analyses will identify risk factors and gastrointestinal complications. Cluster analyses and machine learning will classify different symptoms and co-existing presentations, into a likely diagnosis. We seek biomarkers for autonomic neuropathy by characterizing development of retinopathy using the Visual Function Questionnaire-25 and peripheral neuropathy by the Michigan neuropathy questionnaire. Participants are re-examined yearly for disease progression over time.ResultsFrom focus group studies gastrointestinal symptoms are of major concern in diabetes. Potentially, estimates of symptom prevalence, risk factor identification and classifications of gastrointestinal complications can be unraveled for feedback to health care providers.ConclusionThe web-based DICODI project will open up possibilities to detect gastrointestinal complications of diabetes in a societal setting, benefitting people living with diabetes, health care professionals, and society.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
653 a Celiac disease
653 a complications
653 a gastroenteropathy
653 a gastroparesis
653 a metabolic control
653 a pancreatic exocrine insufficiency
7001 a Karout, Bassamu Milltons Consulting Ltd, Cambridge, England.4 aut
7001 a Torbé, Wiktoria M.u Milltons Consulting Ltd, Cambridge, England.4 aut
7001 a Lunding, Johanu Univ Oslo, Diakonhjemmet Hosp, Oslo, Norway.4 aut
7001 a Wegeberg, Anne-Marieu Aalborg Univ Hosp, Dept Gastroenterol, Mech Sense, Aalborg, Denmark.4 aut
7001 a Drewes, Asbjorn M.u Aalborg Univ Hosp, Dept Gastroenterol, Mech Sense, Aalborg, Denmark.4 aut
7001 a Brock, Christinau Aalborg Univ Hosp, Dept Gastroenterol, Mech Sense, Aalborg, Denmark.;Aalborg Univ, Dept Clin Med, Aalborg, Denmark.4 aut
7001 a Hellström, Per M.,d 1954-u Uppsala universitet,Gastroenterologi/hepatologi4 aut0 (Swepub:uu)perhe742
7102 a Uppsala universitetb Gastroenterologi/hepatologi4 org
7730 t Scandinavian Journal of Gastroenterologyd : Taylor & Francisg 58:1, s. 3-6q 58:1<3-6x 0036-5521x 1502-7708
8564 u https://doi.org/10.1080/00365521.2022.2106149y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1738754/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-496808
8564 8u https://doi.org/10.1080/00365521.2022.2106149

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