WFRF:(Kurland L)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03933naa a2200613 4500 | |
| 001 | oai:research.chalmers.se:f143429f-dc7c-4405-b136-edbdaae237d1 | |
| 003 | SwePub | |
| 008 | 171007s2009 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://doi.org/10.1007/s11745-009-3281-y2 DOI |
| 024 | 7 | a https://research.chalmers.se/publication/1141652 URI |
| 040 | a (SwePub)cth | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Andersson, J.u Akademiska Sjukhuset4 aut |
| 245 | 1 0 | a The Carotid Artery Plaque Size and Echogenicity are Related to Different Cardiovascular Risk Factors in the Elderly |
| 264 | c 2009-02-21 | |
| 264 | 1 | b Wiley,c 2009 |
| 520 | a Carotid plaques can be characterised by ultrasound by size and echogenicity. Both size and echogenicity are predictors of cardiovascular events. The aim of this study was to examine whether traditional risk factors and markers of inflammation and oxidation were associated with plaque size and echogenicity. Computerised analysis of carotid plaque size and echogenicity (grey scale median, GSM) were performed by ultrasound in a population-based health survey in 1,016 subjects aged 70 years (PIVUS study). Information on cardiovascular risk factors was collected, together with markers of inflammation and oxidation. Increased Framingham risk score, systolic blood pressure, higher BMI and decreased HDL, lower glutathione levels were related to echolucent plaques. Previous or present smoking was common with significantly more pack-years related to the echorich plaques. Plaque size was associated with increased Framingham risk score, systolic blood pressure, blood glucose levels, smoking, ApoB/A1 ratio, OxLDL, TNF alpha, HOMA insulin resistance, leucocyte count, decreased BCD-LDL and low levels of l-selectin. Low HDL, increased BMI and decreased glutathione levels were associated with the echolucency of carotid plaques, implying metabolic factors to play a role for plaque composition. Markers of inflammation were related to plaque size alone, implying inflammation to be predominantly associated with the amount of atherosclerosis. These results suggest that plaque size and echogenicity are influenced by different risk factors. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
| 653 | a Carotid artery | |
| 653 | a Atherosclerosis | |
| 653 | a men | |
| 653 | a coronary-heart-disease | |
| 653 | a density-lipoprotein cholesterol | |
| 653 | a atherosclerosis | |
| 653 | a independent predictor | |
| 653 | a prevalence | |
| 653 | a tromso | |
| 653 | a seniors pivus | |
| 653 | a Oxidation | |
| 653 | a Plaque | |
| 653 | a general-population | |
| 653 | a Ultrasound | |
| 653 | a Risk factor | |
| 653 | a count | |
| 653 | a leukocyte | |
| 653 | a uppsala | |
| 653 | a Lipids | |
| 700 | 1 | a Sundstrom, J.u Akademiska Sjukhuset4 aut |
| 700 | 1 | a Kurland, L.u Akademiska Sjukhuset4 aut |
| 700 | 1 | a Gustavsson, Tomas,d 1954u Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)gustav |
| 700 | 1 | a Hulthe, Johannes,d 1970u AstraZeneca AB4 aut |
| 700 | 1 | a Elmgren, A.u AstraZeneca AB4 aut |
| 700 | 1 | a Zilmer, K.u Tartu Ülikool,University of Tartu4 aut |
| 700 | 1 | a Zilmer, M.u Tartu Ülikool,University of Tartu4 aut |
| 700 | 1 | a Lind, L.u Akademiska Sjukhuset4 aut |
| 710 | 2 | a Akademiska Sjukhusetb Chalmers tekniska högskola4 org |
| 773 | 0 | t Lipidsd : Wileyg 44:5, s. 397-403q 44:5<397-403x 0024-4201x 1558-9307 |
| 856 | 4 | u http://dx.doi.org/10.1007/s11745-009-3281-yy FULLTEXT |
| 856 | 4 8 | u https://doi.org/10.1007/s11745-009-3281-y |
| 856 | 4 8 | u https://research.chalmers.se/publication/114165 |
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