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Sökning: WFRF:(Lillicrap D.) > (2010-2014) > Switching clotting ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002912naa a2200445 4500
001oai:lup.lub.lu.se:e2b3e97e-5203-4fe5-9aa6-982df9dd5f36
003SwePub
008160401s2014 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/44702882 URI
024a https://doi.org/10.1111/hae.122832 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Matino, D.4 aut
2451 0a Switching clotting factor concentrates: considerations in estimating the risk of immunogenicity
264 c 2013-10-29
264 1b Wiley,c 2014
520 a The development of neutralizing antibodies to factor VIII (FVIII) is the most serious complication of therapy for haemophilia A. There is now excellent documentation that a large number of both genetic and environmental factors contribute to the risk of FVIII inhibitor incidence. One of the environmental factors that has been proposed as an influence on this complication is the occurrence of FVIII product switching. There are only a small number of clinical studies that have addressed this question, and thus, the amount of objective information available to assess this association is limited. In this review, in addition to summarizing past evidence pertinent to this subject, we present the results of a complementary strategy, a Delphi analysis, to add to the considerations of product switching and FVIII immunogenicity. With the imminent arrival in the clinic of several new FVIII products, the haemophilia community must be prepared to collect prospectively controlled data to better address this important management issue.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng
700a Lillicrap, D.4 aut
700a Astermark, Janu Lund University,Lunds universitet,Klinisk koagulationsmedicin, Malmö,Forskargrupper vid Lunds universitet,Clinical Coagulation, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)medf-jas
700a Dolan, G.4 aut
700a Kessler, C.4 aut
700a Lambert, T.4 aut
700a Makris, M.4 aut
700a O'Donnell, J.4 aut
700a Pipe, S.4 aut
700a Santagostino, E.4 aut
700a Saint-Remy, J. -M.4 aut
700a Schramm, W.4 aut
700a Iorio, A.4 aut
710a Klinisk koagulationsmedicin, Malmöb Forskargrupper vid Lunds universitet4 org
773t Haemophiliad : Wileyg 20:2, s. 200-206q 20:2<200-206x 1351-8216
856u http://dx.doi.org/10.1111/hae.12283y FULLTEXT
856u http://deepblue.lib.umich.edu/bitstream/2027.42/106092/1/hae12283.pdf
8564 8u https://lup.lub.lu.se/record/4470288
8564 8u https://doi.org/10.1111/hae.12283

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