WFRF:(Lu Yuan)
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A clinical study of microcirculatory disturbance in Chinese patients with sudden deafness
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- Lu, Yuan-Yuan (author)
- Karolinska Institutet
- Jin, Zhe (author)
- Tong, Bu-Sheng (author)
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- Yang, Jian-Ming (author)
- Liu, Ye-Hai (author)
- Duan, Maoli (author)
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- (creator_code:org_t)
- 2009-07-08
- 2008
- English.
- In: Acta Oto-Laryngologica. - : Informa UK Limited. - 0001-6489 .- 1651-2251. ; 128:11
- Journal article (peer-reviewed)
Abstract
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- Conclusion. Cochlear microcirculation disturbance is closely associated with sudden deafness. Objectives. To investigate the relationship between cochlear microcirculation and sudden deafness. Subjects and methods. Clinical laboratory parameters (clinical chemistry, hemorheology, hematology, and hemostasis determinations) were studied in 86 patients with sudden deafness and 30 healthy control subjects. Results. The levels of total cholesterol (TCH), triglyceride (TG), and lipoprotein A were significantly higher in patients with sudden deafness than in control subjects. Plasma viscosity, ratio viscosity of whole blood, reduced viscosity of whole blood, high and low shear relative viscosity of whole blood, index of red blood cells transmutation, and fibrinogen level in the plasma of patients with sudden sensorineural hearing loss (SSNHL) were also significantly elevated in comparison with those in control subjects. White-collar workers with psychological and behavioral abnormalities tend to suffer from sudden deafness.
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