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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004742naa a2200889 4500
001oai:gup.ub.gu.se/291558
003SwePub
008240528s2019 | |||||||||||000 ||eng|
024a https://gup.ub.gu.se/publication/2915582 URI
024a https://doi.org/10.1212/wnl.00000000000086122 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Lo, J. W.4 aut
2451 0a Profile of and risk factors for poststroke cognitive impairment in diverse ethnoregional groups
264 c 2019-11-11
264 1b Ovid Technologies (Wolters Kluwer Health),c 2019
520 a Objective To address the variability in prevalence estimates and inconsistencies in potential risk factors for poststroke cognitive impairment (PSCI) using a standardized approach and individual participant data (IPD) from international cohorts in the Stroke and Cognition Consortium (STROKOG) consortium. Methods We harmonized data from 13 studies based in 8 countries. Neuropsychological test scores 2 to 6 months after stroke or TIA and appropriate normative data were used to calculate standardized cognitive domain scores. Domain-specific impairment was based on percentile cutoffs from normative groups, and associations between domain scores and risk factors were examined with 1-stage IPD meta-analysis. Results In a combined sample of 3,146 participants admitted to hospital for stroke (97%) or TIA (3%), 44% were impaired in global cognition and 30% to 35% were impaired in individual domains 2 to 6 months after the index event. Diabetes mellitus and a history of stroke were strongly associated with poorer cognitive function after covariate adjustments; hypertension, smoking, and atrial fibrillation had weaker domain-specific associations. While there were no significant differences in domain impairment among ethnoracial groups, some interethnic differences were found in the effects of risk factors on cognition. Conclusions This study confirms the high prevalence of PSCI in diverse populations, highlights common risk factors, in particular diabetes mellitus, and points to ethnoracial differences that warrant attention in the development of prevention strategies.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng
653 a individual participant data
653 a dementia
653 a stroke
653 a metaanalysis
653 a hypertension
653 a statement
653 a Neurosciences & Neurology
700a Crawford, J. D.4 aut
700a Desmond, D. W.4 aut
700a Godefroy, O.4 aut
700a Jokinen, H.4 aut
700a Mahinrad, S.4 aut
700a Bae, H. J.4 aut
700a Lim, J. S.4 aut
700a Kohler, S.4 aut
700a Douven, E.4 aut
700a Staals, J.4 aut
700a Chen, C.4 aut
700a Xu, X.4 aut
700a Chong, E. J.4 aut
700a Akinyemi, R. O.4 aut
700a Kalaria, R. N.4 aut
700a Ogunniyi, A.4 aut
700a Barbay, M.4 aut
700a Roussel, M.4 aut
700a Lee, B. C.4 aut
700a Srikanth, V. K.4 aut
700a Moran, C.4 aut
700a Kandiah, N.4 aut
700a Chander, R. J.4 aut
700a Sabayan, B.4 aut
700a Jukema, J. W.4 aut
700a Melkas, S.4 aut
700a Erkinjuntti, T.4 aut
700a Brodaty, H.4 aut
700a Bordet, R.4 aut
700a Bombois, S.4 aut
700a Henon, H.4 aut
700a Lipnicki, D. M.4 aut
700a Kochan, N. A.4 aut
700a Sachdev, P. S.4 aut
700a Brodtmann, A.4 aut
700a Klimkowicz-Mrowiec, A.4 aut
700a Dichgans, M.4 aut
700a Hoffmann, M.4 aut
700a Lindén, Thomas,d 1962u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology4 aut0 (Swepub:gu)xlthol
700a Wardlaw, J.4 aut
700a Cordonnier, C.4 aut
700a Mok, V.4 aut
700a Stroke Cognition, Strokog Collabora4 aut
710a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi4 org
773t Neurologyd : Ovid Technologies (Wolters Kluwer Health)g 93:24q 93:24x 0028-3878x 1526-632X
856u https://n.neurology.org/content/neurology/93/24/e2257.full.pdf
8564 8u https://gup.ub.gu.se/publication/291558
8564 8u https://doi.org/10.1212/wnl.0000000000008612

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