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Association between frailty and self-reported health following heart valve surgery
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- Borregaard, Britt (författare)
- Odense Univ Hosp, Denmark; Odense Univ Hosp, Denmark; Univ Southern Denmark, Denmark
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- Dahl, Jordi S. (författare)
- Odense Univ Hosp, Denmark; Univ Southern Denmark, Denmark
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- Lauck, Sandra B. (författare)
- St Pauls Hosp, Canada; Univ British Columbia, Canada
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- (creator_code:org_t)
- ELSEVIER IRELAND LTD, 2020
- 2020
- Engelska.
- Ingår i: IJC Heart & Vasculature. - : ELSEVIER IRELAND LTD. - 2352-9067. ; 31
- Tidskriftsartikel (refereegranskat)
Abstract
Ämnesord
Stäng
- Background: Knowledge about the association between frailty and self-reported health among patients undergoing heart valve surgery remains sparse. Thus, the objectives were to I) describe changes in self-reported health at different time points according to frailty status, and to II) investigate the association between frailty status at discharge and poor self-reported health four weeks after discharge among patients undergoing heart valve surgery. Methods: In a prospective cohort study, consecutive patients undergoing heart valve surgery, including transapical/transaortic valve procedures were included. Frailty was measured using the Fried score, and self-reported health using the Kansas City Cardiomyopathy Questionnaire (KCCQ) and the EuroQoL-5 Dimensions 5-Levels Health Status Questionnaire (EQ-5D-5L). To investigate the association between frailty and self-reported health, multivariable logistic regression models were used. Analyses were adjusted for sex, age, surgical risk evaluation (EuroScore) and procedure and presented as odds ratios (OR) with 95% confidence intervals (CI). Results: Frailty was assessed at discharge in 288 patients (median age 71, 69% men); 51 patients (18%) were frail. In the multivariable analyses, frailty at discharge remained significantly associated with poor self-reported health at four weeks, OR (95% CI): EQ-5D-5L Index 3.38 (1.51-7.52), VAS 2.41 (1.13-5.14), and KCCQ 2.84 (1.35-5.97). Conclusion: Frailty is present at discharge in 18% of patients undergoing heart valve surgery, and being frail is associated with poor self-reported health at four weeks of follow-up. This supports a clinical need to address the unique risk of frail patients among heart valve teams broadly, and not only to measure frailty as a marker of operative risk. (C) 2020 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
Nyckelord
- Heart valves; Cardiac surgery; Frailty; Health-related quality of life
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- Borregaard, Brit ...
- Dahl, Jordi S.
- Lauck, Sandra B.
- Ryg, Jesper
- Berg, Selina K.
- Ekholm, Ola
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- Hendriks, Jeroen
- Riber, Lars P. S ...
- Norekval, Tone M ...
- Moller, Jacob E.
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