SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Pasquini Marcelo)
 

Sökning: WFRF:(Pasquini Marcelo) > Effect of body mass...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003302naa a2200469 4500
001oai:DiVA.org:uu-246896
003SwePub
008150311s2014 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:129831070
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2468962 URI
0247 a https://doi.org/10.1182/blood-2013-03-4903342 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1298310702 URI
040 a (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Aplenc, Richard4 aut
2451 0a Effect of body mass in children with hematologic malignancies undergoing allogeneic bone marrow transplantation.
264 1b American Society of Hematology,c 2014
338 a print2 rdacarrier
520 a The rising incidence of pediatric obesity may significantly affect bone marrow transplantation (BMT) outcomes. We analyzed outcomes in 3687 children worldwide who received cyclophosphamide-based BMT regimens for leukemias between 1990 and 2007. Recipients were classified according to age-adjusted body mass index (BMI) percentiles as underweight (UW), at risk of UW (RUW), normal, overweight (OW), or obese (OB). Median age and race were similar in all groups. Sixty-one percent of OB children were from the United States/Canada. Three-year relapse-free and overall survival ranged from 48% to 52% (P = .54) and 55% to 58% (P = .81) across BMI groups. Three-year leukemia relapses were 33%, 33%, 29%, 25%, and 21% in the UW, RUW, normal, OW, and OB groups, respectively (P < .001). Corresponding cumulative incidences for transplant-related mortality (TRM) were 18%, 19%, 21%, 22%, and 28% (P < .01). Multivariate analysis demonstrated a decreased risk of relapse compared with normal BMI (relative risk [RR] = 0.73; P < .01) and a trend toward higher TRM (RR = 1.28; P = .014). BMI in children is not significantly associated with different survival after BMT for hematologic malignancies. Obese children experience less relapse posttransplant compared with children with normal BMI; however, this benefit is offset by excess in TRM.
7001 a Zhang, Mei-Jie4 aut
7001 a Sung, Lillian4 aut
7001 a Zhu, Xiaochun4 aut
7001 a Ho, Vincent T4 aut
7001 a Cooke, Kenneth4 aut
7001 a Dvorak, Christopher4 aut
7001 a Hale, Gregory4 aut
7001 a Isola, Luis M4 aut
7001 a Lazarus, Hillard M4 aut
7001 a McCarthy, Philip L4 aut
7001 a Olsson, Richardu Karolinska Institutet,Uppsala universitet,Centrum för klinisk forskning i Sörmland (CKFD)4 aut0 (Swepub:uu)riols677
7001 a Pulsipher, Michael4 aut
7001 a Pasquini, Marcelo C4 aut
7001 a Bunin, Nancy4 aut
7102 a Uppsala universitetb Centrum för klinisk forskning i Sörmland (CKFD)4 org
7730 t Bloodd : American Society of Hematologyg 123:22, s. 3504-11q 123:22<3504-11x 0006-4971x 1528-0020
8564 u https://europepmc.org/articles/pmc4041168
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-246896
8564 8u https://doi.org/10.1182/blood-2013-03-490334
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:129831070

Hitta via bibliotek

  • Blood (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy