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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006357naa a2200709 4500
001oai:DiVA.org:liu-86376
003SwePub
008121214s2012 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-863762 URI
0247 a https://doi.org/10.2337/dc12-04382 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Cardwell, Chris Ru Queens University of Belfast, North Ireland4 aut
2451 0a Breast-Feeding and Childhood-Onset Type 1 Diabetes A pooled analysis of individual participant data from 43 observational studies
264 c 2012-10-13
264 1b American Diabetes Association,c 2012
338 a electronic2 rdacarrier
500 a Funding Agencies|National Institutes of Health|R01-DK-46498R01-DK-42316|Chinese Foundation of Health||Department of Health, Executive Yuan, Republic of China|DOH91-TD1167|Ministry for Science and Technology of the Republic of Serbia|175042|German Research Foundation|HE 234/1-1|Research Council of Norway|148359/330|
520 a OBJECTIVE-To investigate if there is a reduced risk of type 1 diabetes in children breastfed or exclusively breastfed by performing a pooled analysis with adjustment for recognized confounders. less thanbrgreater than less thanbrgreater thanRESEARCH DESIGN AND METHODS-Relevant studies were identified from literature searches using MEDLINE, Web of Science, and EMBASE. Authors of relevant studies were asked to provide individual participant data or conduct prespecified analyses. Meta-analysis techniques were used to combine odds ratios (ORs) and investigate heterogeneity between studies. less thanbrgreater than less thanbrgreater thanRESULTS-Data were available from 43 studies including 9,874 patients with type 1 diabetes. Overall, there was a reduction in the risk of diabetes after exclusive breast-feeding for andgt;2 weeks (20 studies; OR = 0.75, 95% CI 0.64-0.88), the association after exclusive breast-feeding for andgt;3 months was weaker (30 studies; OR = 0.87, 95% CI 0.75-1.00), and no association was observed after (nonexclusive) breast-feeding for andgt;2 weeks (28 studies; OR = 0.93, 95% CI 0.81-1.07) or andgt;3 months (29 studies; OR = 0.88, 95% CI 0.78-1.00). These associations were all subject to marked heterogeneity (I-2 = 58, 76, 54, and 68%, respectively). In studies with lower risk of bias, the reduced risk after exclusive breast-feeding for andgt;2 weeks remained (12 studies; OR = 0.86, 95% CI 0.75-0.99), and heterogeneity was reduced (I-2 = 0%). Adjustments for potential confounders altered these estimates very little. less thanbrgreater than less thanbrgreater thanCONCLUSIONS-The pooled analysis suggests weak protective associations between exclusive breast-feeding and type 1 diabetes risk. However, these findings are difficult to interpret because of the marked variation in effect and possible biases (particularly recall bias) inherent in the included studies.
653 a MEDICINE
653 a MEDICIN
7001 a Stene, Lars Cu Norwegian Institute Public Heatlh, Norway Oslo University Hospital, Norway4 aut
7001 a Ludvigsson, Johnnyu Östergötlands Läns Landsting,Linköpings universitet,Pediatrik,Hälsouniversitetet,Barn- och ungdomskliniken i Linköping4 aut0 (Swepub:liu)johlu29
7001 a Rosenbauer, Joachimu University of Dusseldorf, Germany4 aut
7001 a Cinek, Ondreju Charles University of Prague, Czech Republic University Hospital Motol, Czech Republic4 aut
7001 a Svensson, Jannetu Herlev University Hospital, Denmark4 aut
7001 a Perez-Bravo, Franciscou University of Chile, Chile4 aut
7001 a Memon, Anjumu Brighton and Sussex Medical School and NHS Brighton and Hove, England4 aut
7001 a Gimeno, Suely Gu University of Federal Sao Paulo, Brazil4 aut
7001 a Wadsworth, Emma J Ku Cardiff University, Wales4 aut
7001 a Strotmeyer, Elsa Su University of Pittsburgh, PA USA4 aut
7001 a Goldacre, Michael Ju University of Oxford, England4 aut
7001 a Radon, Katjau Hospital Ludwig Maximilian University of Munich, Germany4 aut
7001 a Chuang, Lee-Mingu National Taiwan University Hospital, Taiwan4 aut
7001 a Parslow, Roger Cu University of Leeds, England4 aut
7001 a Chetwynd, Amandau University of Lancaster, England4 aut
7001 a Karavanaki, Kyriakiu University of Athens, Greece4 aut
7001 a Brigis, Girtsu Riga Stradins University, Latvia4 aut
7001 a Pozzilli, Paolou University of Campus Biomed, Italy4 aut
7001 a Urbonaite, Broneu Lithuanian University of Health Science, Lithuania4 aut
7001 a Schober, Edithu Medical University of Vienna, Austria4 aut
7001 a Devoti, Gabrieleu University of Salento, Italy4 aut
7001 a Sipetic, Sandrau University of Belgrade, Serbia4 aut
7001 a Joner, Geiru University of Oslo, Norway Oslo University Hospital, Norway4 aut
7001 a Ionescu-Tirgoviste, Constantinu N Paulescu Institute Diabet, Romania4 aut
7001 a de Beaufort, Carine Eu Clin Pediat Luxembourg, Luxembourg4 aut
7001 a Harrild, Kirstenu University of Aberdeen, Scotland4 aut
7001 a Benson, Victoriau University of Oxford, England4 aut
7001 a Savilahti, Erkkiu University of Helsinki, Finland4 aut
7001 a Ponsonby, Anne-Louiseu Royal Childrens Hospital, Australia4 aut
7001 a Salem, Monau Ain Shams University, Egypt4 aut
7001 a Rabiei, Samirau Shahid Beheshti University of Medical Science and Health Serv, Iran4 aut
7001 a C Patterson, Chrisu Queens University of Belfast, North Ireland4 aut
7102 a Queens University of Belfast, North Irelandb Norwegian Institute Public Heatlh, Norway Oslo University Hospital, Norway4 org
7730 t Diabetes Cared : American Diabetes Associationg 35:11, s. 2215-2225q 35:11<2215-2225x 0149-5992x 1935-5548
8564 u https://liu.diva-portal.org/smash/get/diva2:576894/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://care.diabetesjournals.org/content/diacare/35/11/2215.full.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-86376
8564 8u https://doi.org/10.2337/dc12-0438

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