Sökning: WFRF:(Roberts Christopher J.) > (2010-2014) > Large-scale associa...
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001 | oai:lup.lub.lu.se:7553dae4-0464-42ca-8c45-78d32d2b97af | |
003 | SwePub | |
008 | 160401s2011 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:122295667 | |
024 | 7 | a https://lup.lub.lu.se/record/19250302 URI |
024 | 7 | a https://doi.org/10.1038/ng.7842 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1222956672 URI |
040 | a (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Schunkert, Heribert4 aut |
245 | 1 0 | a Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease |
264 | c 2011-03-06 | |
264 | 1 | b Springer Science and Business Media LLC,c 2011 |
520 | a We performed a meta-analysis of 14 genome-wide association studies of coronary artery disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of European descent followed by genotyping of top association signals in 56,682 additional individuals. This analysis identified 13 loci newly associated with CAD at P < 5 x 10(-8) and confirmed the association of 10 of 12 previously reported CAD loci. The 13 new loci showed risk allele frequencies ranging from 0.13 to 0.91 and were associated with a 6% to 17% increase in the risk of CAD per allele. Notably, only three of the new loci showed significant association with traditional CAD risk factors and the majority lie in gene regions not previously implicated in the pathogenesis of CAD. Finally, five of the new CAD risk loci appear to have pleiotropic effects, showing strong association with various other human diseases or traits. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
700 | 1 | a Koenig, Inke R.4 aut |
700 | 1 | a Kathiresan, Sekar4 aut |
700 | 1 | a Reilly, Muredach P.4 aut |
700 | 1 | a Assimes, Themistocles L.4 aut |
700 | 1 | a Holm, Hilma4 aut |
700 | 1 | a Preuss, Michael4 aut |
700 | 1 | a Stewart, Alexandre F. R.4 aut |
700 | 1 | a Barbalic, Maja4 aut |
700 | 1 | a Gieger, Christian4 aut |
700 | 1 | a Absher, Devin4 aut |
700 | 1 | a Aherrahrou, Zouhair4 aut |
700 | 1 | a Allayee, Hooman4 aut |
700 | 1 | a Altshuler, David4 aut |
700 | 1 | a Anand, Sonia S.4 aut |
700 | 1 | a Andersen, Karl4 aut |
700 | 1 | a Anderson, Jeffrey L.4 aut |
700 | 1 | a Ardissino, Diego4 aut |
700 | 1 | a Ball, Stephen G.u Karolinska Institutet4 aut |
700 | 1 | a Balmforth, Anthony J.4 aut |
700 | 1 | a Barnes, Timothy A.4 aut |
700 | 1 | a Becker, Diane M.4 aut |
700 | 1 | a Becker, Lewis C.4 aut |
700 | 1 | a Berger, Klaus4 aut |
700 | 1 | a Bis, Joshua C.4 aut |
700 | 1 | a Boekholdt, S. Matthijs4 aut |
700 | 1 | a Boerwinkle, Eric4 aut |
700 | 1 | a Braund, Peter S.4 aut |
700 | 1 | a Brown, Morris J.4 aut |
700 | 1 | a Burnett, Mary Susan4 aut |
700 | 1 | a Buysschaert, Ian4 aut |
700 | 1 | a Carlquist, John F.4 aut |
700 | 1 | a Chen, Li4 aut |
700 | 1 | a Cichon, Sven4 aut |
700 | 1 | a Codd, Veryan4 aut |
700 | 1 | a Davies, Robert W.4 aut |
700 | 1 | a Dedoussis, George4 aut |
700 | 1 | a Dehghan, Abbas4 aut |
700 | 1 | a Demissie, Serkalem4 aut |
700 | 1 | a Devaney, Joseph M.4 aut |
700 | 1 | a Diemert, Patrick4 aut |
700 | 1 | a Do, Ron4 aut |
700 | 1 | a Doering, Angela4 aut |
700 | 1 | a Eifert, Sandra4 aut |
700 | 1 | a El Mokhtari, Nour Eddine4 aut |
700 | 1 | a Ellis, Stephen G.4 aut |
700 | 1 | a Elosua, Roberto4 aut |
700 | 1 | a Engert, James C.4 aut |
700 | 1 | a Epstein, Stephen E.4 aut |
700 | 1 | a de Faire, Ulfu Karolinska Institutet4 aut |
700 | 1 | a Fischer, Marcus4 aut |
700 | 1 | a Folsom, Aaron R.4 aut |
700 | 1 | a Freyer, Jennifer4 aut |
700 | 1 | a Gigante, Bruna4 aut |
700 | 1 | a Girelli, Domenico4 aut |
700 | 1 | a Gretarsdottir, Solveig4 aut |
700 | 1 | a Gudnason, Vilmundur4 aut |
700 | 1 | a Gulcher, Jeffrey R.4 aut |
700 | 1 | a Halperin, Eran4 aut |
700 | 1 | a Hammond, Naomi4 aut |
700 | 1 | a Hazen, Stanley L.4 aut |
700 | 1 | a Hofman, Albert4 aut |
700 | 1 | a Horne, Benjamin D.4 aut |
700 | 1 | a Illig, Thomas4 aut |
700 | 1 | a Iribarren, Carlos4 aut |
700 | 1 | a Jones, Gregory T.4 aut |
700 | 1 | a Jukema, J. Wouter4 aut |
700 | 1 | a Kaiser, Michael A.4 aut |
700 | 1 | a Kaplan, Lee M.4 aut |
700 | 1 | a Kastelein, John J. P.4 aut |
700 | 1 | a Khaw, Kay-Tee4 aut |
700 | 1 | a Knowles, Joshua W.4 aut |
700 | 1 | a Kolovou, Genovefa4 aut |
700 | 1 | a Kong, Augustine4 aut |
700 | 1 | a Laaksonen, Reijo4 aut |
700 | 1 | a Lambrechts, Diether4 aut |
700 | 1 | a Leander, Karinu Karolinska Institutet4 aut |
700 | 1 | a Lettre, Guillaume4 aut |
700 | 1 | a Li, Mingyao4 aut |
700 | 1 | a Lieb, Wolfgang4 aut |
700 | 1 | a Loley, Christina4 aut |
700 | 1 | a Lotery, Andrew J.4 aut |
700 | 1 | a Mannucci, Pier M.4 aut |
700 | 1 | a Maouche, Seraya4 aut |
700 | 1 | a Martinelli, Nicola4 aut |
700 | 1 | a McKeown, Pascal P.4 aut |
700 | 1 | a Meisinger, Christa4 aut |
700 | 1 | a Meitinger, Thomas4 aut |
700 | 1 | a Melander, Olleu Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups4 aut0 (Swepub:lu)endo-ome |
700 | 1 | a Merlini, Pier Angelica4 aut |
700 | 1 | a Mooser, Vincent4 aut |
700 | 1 | a Morgan, Thomas4 aut |
700 | 1 | a Muehleisen, Thomas W.4 aut |
700 | 1 | a Muhlestein, Joseph B.4 aut |
700 | 1 | a Muenzel, Thomas4 aut |
700 | 1 | a Musunuru, Kiran4 aut |
700 | 1 | a nahrstaedt, Janja4 aut |
700 | 1 | a Nelson, Christopher P.4 aut |
700 | 1 | a Noethen, Markus M.4 aut |
700 | 1 | a Olivieri, Oliviero4 aut |
700 | 1 | a Patel, Riyaz S.4 aut |
700 | 1 | a Patterson, Chris C.4 aut |
700 | 1 | a Peters, Annette4 aut |
700 | 1 | a Peyvandi, Flora4 aut |
700 | 1 | a Qu, Liming4 aut |
700 | 1 | a Quyyumi, Arshed A.4 aut |
700 | 1 | a Rader, Daniel J.4 aut |
700 | 1 | a Rallidis, Loukianos S.4 aut |
700 | 1 | a Rice, Catherine4 aut |
700 | 1 | a Rosendaal, Frits R.4 aut |
700 | 1 | a Rubin, Diana4 aut |
700 | 1 | a Salomaa, Veikko4 aut |
700 | 1 | a Sampietro, M. Lourdes4 aut |
700 | 1 | a Sandhu, Manj S.4 aut |
700 | 1 | a Schadt, Eric4 aut |
700 | 1 | a Schaefer, Arne4 aut |
700 | 1 | a Schillert, Arne4 aut |
700 | 1 | a Schreiber, Stefan4 aut |
700 | 1 | a Schrezenmeir, Juergen4 aut |
700 | 1 | a Schwartz, Stephen M.4 aut |
700 | 1 | a Siscovick, David S.4 aut |
700 | 1 | a Sivananthan, Mohan4 aut |
700 | 1 | a Sivapalaratnam, Suthesh4 aut |
700 | 1 | a Smith, Albert4 aut |
700 | 1 | a Smith, Tamara B.4 aut |
700 | 1 | a Snoep, Jaapjan D.4 aut |
700 | 1 | a Soranzo, Nicole4 aut |
700 | 1 | a Spertus, John A.4 aut |
700 | 1 | a Stark, Klaus4 aut |
700 | 1 | a Stirrups, Kathy4 aut |
700 | 1 | a Stoll, Monika4 aut |
700 | 1 | a Tang, W. H. Wilson4 aut |
700 | 1 | a Tennstedt, Stephanie4 aut |
700 | 1 | a Thorgeirsson, Gudmundur4 aut |
700 | 1 | a Thorleifsson, Gudmar4 aut |
700 | 1 | a Tomaszewski, Maciej4 aut |
700 | 1 | a Uitterlinden, Andre G.4 aut |
700 | 1 | a van Rij, Andre M.4 aut |
700 | 1 | a Voight, Benjamin F.4 aut |
700 | 1 | a Wareham, Nick J.4 aut |
700 | 1 | a Wells, George A.4 aut |
700 | 1 | a Wichmann, H-Erich4 aut |
700 | 1 | a Wild, Philipp S.4 aut |
700 | 1 | a Willenborg, Christina4 aut |
700 | 1 | a Witteman, Jaqueline C. M.4 aut |
700 | 1 | a Wright, Benjamin J.4 aut |
700 | 1 | a Ye, Shu4 aut |
700 | 1 | a Zeller, Tanja4 aut |
700 | 1 | a Ziegler, Andreas4 aut |
700 | 1 | a Cambien, Francois4 aut |
700 | 1 | a Goodall, Alison H.4 aut |
700 | 1 | a Cupples, L. Adrienne4 aut |
700 | 1 | a Quertermous, Thomas4 aut |
700 | 1 | a Maerz, Winfried4 aut |
700 | 1 | a Hengstenberg, Christian4 aut |
700 | 1 | a Blankenberg, Stefan4 aut |
700 | 1 | a Ouwehand, Willem H.4 aut |
700 | 1 | a Hall, Alistair S.4 aut |
700 | 1 | a Deloukas, Panos4 aut |
700 | 1 | a Thompson, John R.4 aut |
700 | 1 | a Stefansson, Kari4 aut |
700 | 1 | a Roberts, Robert4 aut |
700 | 1 | a Thorsteinsdottir, Unnur4 aut |
700 | 1 | a O'Donnell, Christopher J.4 aut |
700 | 1 | a McPherson, Ruth4 aut |
700 | 1 | a Erdmann, Jeanette4 aut |
700 | 1 | a Samani, Nilesh J.4 aut |
710 | 2 | a Karolinska Institutetb Kardiovaskulär forskning - hypertoni4 org |
773 | 0 | t Nature Geneticsd : Springer Science and Business Media LLCg 43:4, s. 153-333q 43:4<153-333x 1546-1718x 1061-4036 |
856 | 4 | u http://dx.doi.org/10.1038/ng.784y FULLTEXT |
856 | 4 | u https://europepmc.org/articles/pmc3119261?pdf=render |
856 | 4 8 | u https://lup.lub.lu.se/record/1925030 |
856 | 4 8 | u https://doi.org/10.1038/ng.784 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:122295667 |
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