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Echocardiographic f...
Echocardiographic findings predict in-hospital and 1-year mortality in left-sided native valve Staphylococcus aureus endocarditis: Analysis from the international collaboration on endocarditis-prospective echo cohort study
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Lauridsen, T. K. (författare)
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Park, L. (författare)
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Tong, S. Y. C. (författare)
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Selton-Suty, C. (författare)
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Peterson, G. (författare)
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Cecchi, E. (författare)
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Afonso, L. (författare)
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Habib, G. (författare)
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Paré, C. (författare)
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Tamin, S. (författare)
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Dickerman, S. (författare)
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Bayer, A. S. (författare)
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- Johansson, Magnus C, 1954 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine
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Chu, V. H. (författare)
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Samad, Z. (författare)
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Bruun, N. E. (författare)
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Fowler, V. G., Jr. (författare)
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Crowley, A. L. (författare)
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(creator_code:org_t)
- 2015
- 2015
- Engelska.
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Ingår i: Circulation Cardiovascular Imaging. - 1941-9651. ; 8:7
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Background: Staphylococcus aureus left-sided native valve infective endocarditis (LNVIE) has higher complication and mortality rates compared with endocarditis from other pathogens. Whether echocardiographic variables can predict prognosis in S aureus LNVIE is unknown. Methods and Results: Consecutive patients with LNVIE, enrolled between January 2000 and September 2006, in the International Collaboration on Endocarditis were identified. Subjects without S aureus IE were matched to those with S aureus IE by the propensity of having S aureus. Survival differences were determined using log-rank significance tests. Independent echocardiographic predictors of mortality were identified using Cox-proportional hazards models that included inverse probability of treatment weighting and surgery as a time-dependent covariate. Of 727 subjects with LNVIE and 1-year follow-up, 202 had S aureus IE. One-year survival rates were significantly lower for patients with S aureus IE overall (57% S aureus IE versus 80% non-S aureus IE; P<0.001) and in the propensity-matched cohort (59% S aureus IE versus 68% non-S aureus IE; P<0.05). Intracardiac abscess (hazard ratio, 2.93; 95% confidence interval, 1.52-5.40; P<0.001) and left ventricular ejection fraction <40% (odds ratio, 3.01; 95% confidence interval, 1.35-6.04; P=0.004) were the only independent echocardiographic predictors of in-hospital mortality in S aureus LNVIE. Valve perforation (hazard ratio, 2.16; 95% confidence interval, 1.21-3.68; P=0.006) and intracardiac abscess (hazard ratio, 2.25; 95% confidence interval, 1.26-3.78; P=0.004) were the only independent predictors of 1-year mortality. Conclusions: S aureus is an independent predictor of 1-year mortality in subjects with LNVIE. In S aureus LNVIE, intracardiac abscess and left ventricular ejection fraction <40% independently predicted in-hospital mortality and intracardiac abscess and valve perforation independently predicted 1-year mortality. © 2015 American Heart Association, Inc.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Echocardiography
- Endocarditis
- Odds ratio
- Risk factors
- Survival analysis
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Lauridsen, T. K.
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Park, L.
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Tong, S. Y. C.
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Selton-Suty, C.
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Peterson, G.
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Cecchi, E.
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visa fler...
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Afonso, L.
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Habib, G.
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Paré, C.
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Tamin, S.
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Dickerman, S.
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Bayer, A. S.
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Johansson, Magnu ...
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Chu, V. H.
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Samad, Z.
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Bruun, N. E.
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Fowler, V. G., J ...
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Crowley, A. L.
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visa färre...
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Göteborgs universitet