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Genome-wide associa...
Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk
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Orr, Nick (author)
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Lemnrau, Alina (author)
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Cooke, Rosie (author)
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show more...
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Fletcher, Olivia (author)
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Tomczyk, Katarzyna (author)
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Jones, Michael (author)
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Johnson, Nichola (author)
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Lord, Christopher J. (author)
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Mitsopoulos, Costas (author)
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Zvelebil, Marketa (author)
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McDade, Simon S. (author)
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Buck, Gemma (author)
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Blancher, Christine (author)
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Trainer, Alison H. (author)
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James, Paul A. (author)
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Bojesen, Stig E. (author)
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Bokmand, Susanne (author)
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Nevanlinna, Heli (author)
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Mattson, Johanna (author)
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Friedman, Eitan (author)
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Laitman, Yael (author)
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Palli, Domenico (author)
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Masala, Giovanna (author)
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Zanna, Ines (author)
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Ottini, Laura (author)
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Giannini, Giuseppe (author)
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Hollestelle, Antoinette (author)
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van den Ouweland, Ans M. W. (author)
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Novakovic, Srdjan (author)
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Krajc, Mateja (author)
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Gago-Dominguez, Manuela (author)
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Castelao, Jose Esteban (author)
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- Olsson, Håkan (author)
- Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Hedenfalk, Ingrid (author)
- Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Bröst- och ovarialcancer,Forskargrupper vid Lunds universitet,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Breast and Ovarian Cancer Genomics,Lund University Research Groups
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Easton, Douglas F. (author)
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Pharoah, Paul D. P. (author)
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Dunning, Alison M. (author)
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Bishop, D. Timothy (author)
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Neuhausen, Susan L. (author)
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Steele, Linda (author)
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Houlston, Richard S. (author)
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Garcia-Closas, Montserrat (author)
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Ashworth, Alan (author)
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Swerdlow, Anthony J. (author)
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(creator_code:org_t)
- 2012-09-23
- 2012
- English.
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In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 44:11, s. 1182-1184
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Abstract
Subject headings
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- We conducted a genome-wide association study of male breast cancer comprising 823 cases and 2,795 controls of European ancestry, with validation in independent sample sets totaling 438 cases and 474 controls. A SNP in RAD51B at 14q24.1 was significantly associated with male breast cancer risk (P = 3.02 x 10(-13); odds ratio (OR) = 1.57). We also refine association at 16q12.1 to a SNP within TOX3 (P = 3.87 x 10(-15); OR = 1.50).
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
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- art (subject category)
- ref (subject category)
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- By the author/editor
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Orr, Nick
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Lemnrau, Alina
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Cooke, Rosie
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Fletcher, Olivia
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Tomczyk, Katarzy ...
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Jones, Michael
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show more...
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Johnson, Nichola
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Lord, Christophe ...
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Mitsopoulos, Cos ...
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Zvelebil, Market ...
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McDade, Simon S.
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Buck, Gemma
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Blancher, Christ ...
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Trainer, Alison ...
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James, Paul A.
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Bojesen, Stig E.
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Bokmand, Susanne
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Nevanlinna, Heli
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Mattson, Johanna
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Friedman, Eitan
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Laitman, Yael
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Palli, Domenico
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Masala, Giovanna
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Zanna, Ines
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Ottini, Laura
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Giannini, Giusep ...
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Hollestelle, Ant ...
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van den Ouweland ...
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Novakovic, Srdja ...
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Krajc, Mateja
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Gago-Dominguez, ...
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Castelao, Jose E ...
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Olsson, Håkan
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Hedenfalk, Ingri ...
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Easton, Douglas ...
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Pharoah, Paul D. ...
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Dunning, Alison ...
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Bishop, D. Timot ...
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Neuhausen, Susan ...
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Steele, Linda
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Houlston, Richar ...
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Garcia-Closas, M ...
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Ashworth, Alan
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Swerdlow, Anthon ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
- Articles in the publication
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Nature Genetics
- By the university
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Lund University