WFRF:(Werner Maria 1957)
Sökning: WFRF:(Werner Maria 1957) > Systemic symptoms p...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03296naa a2200349 4500 | |
| 001 | oai:gup.ub.gu.se/227290 | |
| 003 | SwePub | |
| 008 | 240528s2016 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/2272902 URI |
| 024 | 7 | a https://doi.org/10.3109/23744235.2015.11047192 DOI |
| 040 | a (SwePub)gu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Edman-Wallér, Jon4 aut |
| 245 | 1 0 | a Systemic symptoms predict presence or development of severe sepsis and septic shock |
| 264 | c 2015-10-22 | |
| 264 | 1 | b Informa UK Limited,c 2016 |
| 520 | a Severe sepsis is a major cause of mortality and morbidity globally. As the time to adequate treatment is directly linked to outcome, early recognition is of critical importance. Early, accessible markers for severe sepsis are desirable. The systemic inflammatory response in sepsis leads to changes in vital signs and biomarkers and to symptoms unrelated to the focus of infection. This study investigated whether the occurrence of any of six systemic symptoms could predict severe sepsis in a cohort of patients admitted to hospital for suspected bacterial infections. Methods: A retrospective, consecutive study was conducted. All adult patients admitted during 1 month to a 550-bed secondary care hospital in western Sweden and given intravenous antibiotics for suspected community-acquired infection were included (n=289). Symptoms (fever/chills, muscle weakness, localised pain, dyspnea, altered mental status and gastrointestinal symptoms) were registered along with age, sex, vital signs and laboratory values. Patients who fulfilled criteria of severe sepsis within 48 h were compared with patients who did not. Odds ratios for severe sepsis were calculated, adjusted for age, sex and comorbidities. Results: Criteria for severe sepsis were fulfilled by 90/289 patients (31.1%). Altered mental status (OR=4.29, 95% CI=2.03–9.08), dyspnea (OR=2.92, 95% CI=1.69–5.02), gastrointestinal symptoms (OR=2.31, 95% CI=1.14–4.69) and muscle weakness (OR=2.24, 95% CI=1.06–4.75) were more common in patients who had or later developed severe sepsis. Conclusions: Systemic symptoms in combination with other signs of infection should be considered warning signs of severe sepsis. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng |
| 653 | a sepsis | |
| 653 | a symptoms | |
| 700 | 1 | a Ljungström, Lars4 aut |
| 700 | 1 | a Jacobsson, Gunnar,d 19604 aut |
| 700 | 1 | a Andersson, Rune,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine4 aut0 (Swepub:gu)xandru |
| 700 | 1 | a Werner, Maria,d 19574 aut |
| 710 | 2 | a Göteborgs universitetb Institutionen för biomedicin, avdelningen för infektionssjukdomar4 org |
| 773 | 0 | t Infectious Diseasesd : Informa UK Limitedg 48:3, s. 209-214q 48:3<209-214x 2374-4235x 2374-4243 |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/227290 |
| 856 | 4 8 | u https://doi.org/10.3109/23744235.2015.1104719 |
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