WFRF:(Wide Swensson Dag)
Sökning: WFRF:(Wide Swensson Dag) > Sublingual misopros...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04950naa a2200409 4500 | |
| 001 | oai:lup.lub.lu.se:a45d840e-d4e4-42d3-9d4d-bf8e13343f05 | |
| 003 | SwePub | |
| 008 | 221212s2022 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/a45d840e-d4e4-42d3-9d4d-bf8e13343f052 URI |
| 024 | 7 | a https://doi.org/10.3389/fsurg.2022.9683722 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Amini, Mahdiu Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Valid intrapartal övervakning och intervention för perinatal säkerhet,Forskargrupper vid Lunds universitet,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Valid IntraPartum Surveillance and Interventions to make Pregnancy Safe,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)ma4640am |
| 245 | 1 0 | a Sublingual misoprostol vs. oral misoprostol solution for induction of labor : A retrospective study |
| 264 | c 2022-09-15 | |
| 264 | 1 | b Frontiers Media SA,c 2022 |
| 520 | a Introduction: Induction of labor (IOL) is one of the most common obstetrical procedures, with an increasing rate. The prostaglandin E1 analogue misoprostol is frequently used as a primary method of labor induction. The optimal dose and route of administration is yet to be ascertained. Aim: To compare efficiacy and safety between a regimen of sublingually administered misoprostol and a regimen of orally administered misoprostol, with cesarean delivery as primary outcome. Methods: A retrospective study was conducted including women carrying a live, singleton fetus in a cephalic position with labor induced at >37 + 0 gestational weeks at Skåne University hospital, Lund, between January 1st 2013 to December 31st 2017. Data was obtained from computerized obstetrical charts. Results: Totally 2,404 women were included; 974 induced with sublingual misoprostol and 1,430 with oral solution. In primiparous women the cesarean delivery rate was lower in primiparous women induced with oral compared to sublingual misoprostol (20.5% vs. 28.6%, p < 0.001), whereas in parous women the rates did not differ significantly 4.9% vs. 7.5%; NS). The increased risk of caesarean remained after controlling for potential confounding factors (adjusted odds ratio 1.49 (1.14–1.95). Women induced with sublingual misoprostol had a shorter time to vaginal delivery when compared to oral solution (primiparous median 16.7 h vs. 21.7 h; p < 0.001, parous median 9.9 h vs. 13.3 h; p = 0.01), and a higher rate of vaginal delivery within 24 h (primiparas 77.7% vs. 63.3%, p < 0.001, parous 93.2% vs. 84.2%; p = 0.01). Conclusion: IOL with oral misoprostol solution was associated with a significantly higher vaginal delivery rate when compared to sublingual misoprostol, whereas sublingual misoprostol was associated with a significantly shorter time from induction to vaginal delivery. Oral administration is considered the most safe and efficient administration of misoprostol, although more studies are needed to find the optimal route and dosage of misoprostol for IOL. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng |
| 653 | a human | |
| 653 | a induction of labour | |
| 653 | a misoprostol | |
| 653 | a oral | |
| 653 | a oral misoprostol solution | |
| 653 | a pregnancy | |
| 653 | a retrospective | |
| 653 | a sublingual | |
| 700 | 1 | a Wide-Swensson, Dagu Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)gyn-dws |
| 700 | 1 | a Herbst, Andreasu Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Valid intrapartal övervakning och intervention för perinatal säkerhet,Forskargrupper vid Lunds universitet,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Valid IntraPartum Surveillance and Interventions to make Pregnancy Safe,Lund University Research Groups4 aut0 (Swepub:lu)gyn-ahe |
| 710 | 2 | a Obstetrik och gynekologi, Lundb Sektion V4 org |
| 773 | 0 | t Frontiers in surgeryd : Frontiers Media SAg 9q 9x 2296-875X |
| 856 | 4 | u http://dx.doi.org/10.3389/fsurg.2022.968372x freey FULLTEXT |
| 856 | 4 8 | u https://lup.lub.lu.se/record/a45d840e-d4e4-42d3-9d4d-bf8e13343f05 |
| 856 | 4 8 | u https://doi.org/10.3389/fsurg.2022.968372 |
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