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Sökning: WFRF:(Shchukarev Andrey) > Cryo-XPS for surfac...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003311naa a2200421 4500
001oai:DiVA.org:umu-215315
003SwePub
008231017s2023 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2153152 URI
0247 a https://doi.org/10.1021/acs.jpca.3c038792 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Cant, David J. H.u National Physical Laboratory, Teddington, UK4 aut
2451 0a Cryo-XPS for surface characterization of nanomedicines
264 1b American Chemical Society (ACS),c 2023
338 a print2 rdacarrier
520 a Nanoparticles used for medical applications commonly possess coatings or surface functionalities intended to provide specific behavior in vivo, for example, the use of PEG to provide stealth properties. Direct, quantitative measurement of the surface chemistry and composition of such systems in a hydrated environment has thus far not been demonstrated, yet such measurements are of great importance for the development of nanomedicine systems. Here we demonstrate the first use of cryo-XPS for the measurement of two PEG-functionalized nanomedicines: a polymeric drug delivery system and a lipid nanoparticle mRNA carrier. The observed differences between cryo-XPS and standard XPS measurements indicate the potential of cryo-XPS for providing quantitative measurements of such nanoparticle systems in hydrated conditions.
650 7a NATURVETENSKAPx Kemix Analytisk kemi0 (SwePub)104012 hsv//swe
650 7a NATURAL SCIENCESx Chemical Sciencesx Analytical Chemistry0 (SwePub)104012 hsv//eng
650 7a NATURVETENSKAPx Kemix Materialkemi0 (SwePub)104032 hsv//swe
650 7a NATURAL SCIENCESx Chemical Sciencesx Materials Chemistry0 (SwePub)104032 hsv//eng
7001 a Pei, Yiwenu National Physical Laboratory, Teddington, UK4 aut
7001 a Shchukarev, Andreyu Umeå universitet,Kemiska institutionen4 aut0 (Swepub:umu)ansh0001
7001 a Ramstedt, Madeleineu Umeå universitet,Kemiska institutionen4 aut0 (Swepub:umu)maerat95
7001 a Marques, Sara S.u Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal4 aut
7001 a Segundo, Marcela A.u Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal4 aut
7001 a Parot, Jeremieu Department of Biotechnology and Nanomedicine, SINTEF Industry, Trondheim, Norway4 aut
7001 a Molska, Alicjau Department of Biotechnology and Nanomedicine, SINTEF Industry, Trondheim, Norway4 aut
7001 a Borgos, Sven E.u Department of Biotechnology and Nanomedicine, SINTEF Industry, Trondheim, Norway4 aut
7001 a Shard, Alexander G.u National Physical Laboratory, Teddington, UK4 aut
7001 a Minelli, Caterinau National Physical Laboratory, Teddington, UK4 aut
7102 a National Physical Laboratory, Teddington, UKb Kemiska institutionen4 org
7730 t Journal of Physical Chemistry Ad : American Chemical Society (ACS)g 127:39, s. 8220-8227q 127:39<8220-8227x 1089-5639x 1520-5215
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-215315
8564 8u https://doi.org/10.1021/acs.jpca.3c03879

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