Associations Between General and Abdominal Adiposity and Mortality in Individuals With Diabetes Mellitus

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Fältnamn	Indikatorer	Metadata
000		05013naa a2200733 4500
001		oai:lup.lub.lu.se:e59b6ce4-a869-4b71-979a-64c6b5150fb8
003		SwePub
008		160401s2011 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:DiVA.org:umu-44343
024	7	a https://lup.lub.lu.se/record/20493642 URI
024	7	a https://doi.org/10.1093/aje/kwr0482 DOI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-443432 URI
040		a (SwePub)lud (SwePub)umu
041		a engb eng
042		9 SwePub
072	7	a art2 swepub-publicationtype
072	7	a ref2 swepub-contenttype
100	1	a Sluik, Diewertje4 aut
245	1 0	a Associations Between General and Abdominal Adiposity and Mortality in Individuals With Diabetes Mellitus
264		c 2011-05-26
264	1	a Cary :b Oxford University Press (OUP),c 2011
520		a Individuals with diabetes mellitus are advised to achieve a healthy weight to prevent complications. However, fat mass distribution has hardly been investigated as a risk factor for diabetes complications. The authors studied associations between body mass index, waist circumference, waist/hip ratio, and waist/height ratio and mortality among individuals with diabetes mellitus. Within the European Prospective Investigation into Cancer and Nutrition, a subcohort was defined as 5,435 individuals with a confirmed self-report of diabetes mellitus at baseline in 1992-2000. Participants were aged 57.3 (standard deviation, 6.3) years, 54% were men, the median diabetes duration was 4.6 (interquartile range, 2.0-9.8) years, and 22% of the participants used insulin. Body mass index, as indicator of general obesity, was not associated with higher mortality, whereas all measurements of abdominal obesity showed a positive association. Associations generally were slightly weaker in women. The strongest association was observed for waist/height ratio: In the fifth quintile, the hazard rate ratio was 1.88 (95% confidence interval: 1.33, 2.65) for men and 2.46 (95% confidence interval: 1.46, 4.14) for women. Measurements of abdominal, but not general, adiposity were associated with higher mortality in diabetic individuals. The waist/height ratio showed the strongest association. Respective indicators might be investigated in risk prediction models.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
653		a adiposity
653		a body mass index
653		a diabetes complications
653		a diabetes mellitus
653		a mortality
653		a waist circumference
653		a waist-hip ratio
653		a adiposity
700	1	a Boeing, Heiner4 aut
700	1	a Montonen, Jukka4 aut
700	1	a Pischon, Tobias4 aut
700	1	a Kaaks, Rudolf4 aut
700	1	a Teucher, Birgit4 aut
700	1	a Tjonneland, Anne4 aut
700	1	a Halkjaer, Jytte4 aut
700	1	a Berentzen, Tina L.4 aut
700	1	a Overvad, Kim4 aut
700	1	a Arriola, Larraitz4 aut
700	1	a Ardanaz, Eva4 aut
700	1	a Bendinelli, Benedetta4 aut
700	1	a Grioni, Sara4 aut
700	1	a Tumino, Rosario4 aut
700	1	a Sacerdote, Carlotta4 aut
700	1	a Mattiello, Amalia4 aut
700	1	a Spijkerman, Annemieke M. W.4 aut
700	1	a van der A, Daphne L.4 aut
700	1	a Beulens, Joline W.4 aut
700	1	a van der Schouw, Yvonne T.4 aut
700	1	a Nilsson, Peteru Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)medf-pni
700	1	a Hedblad, Bou Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)medf-bhe
700	1	a Rolandsson, Olovu Umeå universitet,Allmänmedicin4 aut0 (Swepub:umu)olro0005
700	1	a Franks, Paulu Umeå universitet,Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,Medicin4 aut0 (Swepub:umu)pafr0003
700	1	a Noethlings, Ute4 aut
710	2	a Internmedicin - epidemiologib Forskargrupper vid Lunds universitet4 org
773	0	t American Journal of Epidemiologyd Cary : Oxford University Press (OUP)g 174:1, s. 22-34q 174:1<22-34x 0002-9262x 1476-6256
856	4	u http://dx.doi.org/10.1093/aje/kwr048y FULLTEXT
856	4	u https://academic.oup.com/aje/article-pdf/174/1/22/294276/kwr048.pdf
856	4 8	u https://lup.lub.lu.se/record/2049364
856	4 8	u https://doi.org/10.1093/aje/kwr048
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-44343

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