Cephalometric analysis of adults with Turner syndrome

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Fältnamn	Indikatorer	Metadata
000		05901naa a2200385 4500
001		oai:DiVA.org:liu-128984
003		SwePub
008		160607s2016 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:DiVA.org:oru-110286
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1289842 URI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-1102862 URI
040		a (SwePub)liud (SwePub)oru
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Svanberg, Christinau Region Östergötland, Folktandvården,Centre for Orthodontics and Paediatric Dentistry, Linköping, County Council of Östergötland, Sweden; Department of Orthodontics, Östersund, County Council of Jämtland, Sweden,Ctr Orthodont and Paediat Dent4 aut
245	1 0	a Cephalometric analysis of adults with Turner syndrome
264	1	b SWEDISH DENTAL JOURNAL,c 2016
338		a print2 rdacarrier
500		a Funding Agencies\|Folktandvarden Ostergotland; Medical Research Council of Southeast Sweden
520		a Turner syndrome (TS) is a genetic disorder of females with a prevalence of 1/2000-3000 live female births. The aim of this study was to compare cephalometric variables from adult women diagnosed with TS to a standardized reference group of 31-year old healthy women, and to evaluate the possible effects of human growth hormone (hGH) therapy in women with TS. Registered TS subjects in the Southeast region of Sweden were invited to take part in the study. Twenty-one women aged 36 +/- 13(18-57) years accepted participation. Lateral radiographs of the head were analyzed using standard cephalometric methods (Hasund analysis) and with the commercially available soft-ware program FACAD. Comparisons were made with roentgen-cephalometric standards from a reference group of nineteen 31-year old Swedish women. Analysis of the cephalometric radiographs from the TS subjects showed a more retrognathic maxilla (SNA 80.3 +/- 5.4) (p=0.0460) and mandible (SNB 77.0 +/- 5.2) (p=0.0014), and a correspondingly backward position of the chin (SN/Pg 78.9 +/- 5.5) (p=0.0046) as compared to the reference values of 31-year old women (SNA 83.2 +/- 3.0, SNB 81.5 +/- 2.3 and SNPg 83.0 +/- 2.3, respectively). In addition there was an increased posterior inclination of the maxilla (SN/NL 8.6 +/- 4.1), as compared to the reference values (SN/NL 5,3 +/- 2.7) (p=0.0048). There were no significant differences regarding sagittal or vertical jaw relations, mandibular inclination or cranial base angle between the TS-group and the 31-year olds with the reference values. No significant difference was seen in jaw relationship, as measured by the ANB value, however the Wits(index) (3.3 +/- 3.5) was higher (p=0.0001) than the reference values (-0.1 +/- 1.8). Subjects with or without previous hGH administration did not show any significant differences in cephalometric values. In conclusion, women with TS had a significantly more retrognathic maxilla (SNA) and mandible (SNB) and a correspondingly significantly posterior position of the chin (SN/Pg), a significantly increased posterior inclination of the maxilla (SN/NL) and a significantly increased Witsindex as compared to the reference group of 31-year old women. No craniofacial variables differed significantly between previously hGH-treated and not hGH-treated women with TS.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Odontologi0 (SwePub)302162 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dentistry0 (SwePub)302162 hsv//eng
653		a Turner syndrome; cephalometric analysis; growth hormone
700	1	a Norevall, Lars-Ingeu Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Centre for Orthodontics and Paediatric Dentistry, Linköping, County Council of Östergötland, Sweden4 aut0 (Swepub:liu)larno12
700	1	a Ekman, Bertilu Linköpings universitet,Medicinska fakulteten,Avdelningen för kardiovaskulär medicin,Region Östergötland, Endokrinmedicinska kliniken,Section of Endocrinology, Division of Cardiovascular Medicine, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, Sweden4 aut0 (Swepub:liu)berek83
700	1	a Wahlberg Topp, Jeanetteu Linköpings universitet,Medicinska fakulteten,Avdelningen för kardiovaskulär medicin,Region Östergötland, Endokrinmedicinska kliniken,Section of Endocrinology, Division of Cardiovascular Medicine, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, Sweden4 aut0 (Swepub:oru)jewg
700	1	a Bågesund, Matsu Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Folktandvården,Centre for Orthodontics and Paediatric Dentistry, Norrköping, Public Dental Service Östergötland, County Council of Östergötland, Sweden; Division of Pediatrics, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden4 aut0 (Swepub:liu)matba36
710	2	a Region Östergötland, Folktandvårdenb Centre for Orthodontics and Paediatric Dentistry, Linköping, County Council of Östergötland, Sweden; Department of Orthodontics, Östersund, County Council of Jämtland, Sweden4 org
773	0	t Swedish Dental Journald : SWEDISH DENTAL JOURNALg 40:1, s. 33-41q 40:1<33-41x 0347-9994
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-128984
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-110286

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Av författaren/redakt...: Svanberg, Christ ...; Norevall, Lars-I ...; Ekman, Bertil; Wahlberg Topp, J ...; Bågesund, Mats

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