Surgical management of acute appendicitis during the European COVID-19 second wave: safe and effective

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Fältnamn	Indikatorer	Metadata
000		09678naa a2201657 4500
001		oai:gup.ub.gu.se/331761
003		SwePub
008		240528s2023 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:DiVA.org:oru-103312
009		oai:prod.swepub.kib.ki.se:151680339
024	7	a https://gup.ub.gu.se/publication/3317612 URI
024	7	a https://doi.org/10.1007/s00068-022-02149-w2 DOI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-1033122 URI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1516803392 URI
040		a (SwePub)gud (SwePub)orud (SwePub)ki
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Forssten, Maximilian Peter,d 1996-u Örebro universitet,Institutionen för medicinska vetenskaper,Division of Trauma and Emergency Surgery, Örebro University Hospital, Örebro University, Örebro, Sweden4 aut0 (Swepub:oru)mmfn
245	1 0	a Surgical management of acute appendicitis during the European COVID-19 second wave: safe and effective
264		c 2023-01-19
264	1	b Springer Science and Business Media LLC,c 2023
520		a Introduction: The COVID-19 (SARS-CoV-2) pandemic drove acute care surgeons to pivot from long established practice patterns. Early safety concerns regarding increased postoperative complication risk in those with active COVID infection promoted antibiotic-driven non-operative therapy for select conditions ahead of an evidence-base. Our study assesses whether active or recent SARS-CoV-2 positivity increases hospital length of stay (LOS) or postoperative complications following appendectomy. Methods: Data were derived from the prospective multi-institutional observational SnapAppy cohort study. This preplanned data analysis assessed consecutive patients aged ≥ 15years who underwent appendectomy for appendicitis (November 2020–May 2021). Patients were categorized based on SARS-CoV-2 seropositivity: no infection, active infection, and prior infection. Appendectomy method, LOS, and complications were abstracted. The association between SARS-CoV-2 seropositivity and complications was determined using Poisson regression, while the association with LOS was calculated using a quantile regression model. Results: Appendectomy for acute appendicitis was performed in 4047 patients during the second and third European COVID waves. The majority were SARS-CoV-2 uninfected (3861, 95.4%), while 70 (1.7%) were acutely SARS-CoV-2 positive, and 116 (2.8%) reported prior SARS-CoV-2 infection. After confounder adjustment, there was no statistically significant association between SARS-CoV-2 seropositivity and LOS, any complication, or severe complications. Conclusion: During sequential SARS-CoV-2 infection waves, neither active nor prior SARS-CoV-2 infection was associated with prolonged hospital LOS or postoperative complication. Despite early concerns regarding postoperative safety and outcome during active SARS-CoV-2 infection, no such association was noted for those with appendicitis who underwent operative management.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng
653		a Acute appendicitis
653		a Appendectomy
653		a COVID-19
653		a Observational cohort
653		a Outcomes
653		a Acute appendicitis
700	1	a Kaplan, Lewis J.u Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA; Corporal Michael Crescenz Veterans Affairs Medical Center, Philadelphia, USA4 aut
700	1	a Tolonen, Mattiu Helsinki University Hospital HUS Meilahden Tornisairaala, Helsinki, Finland4 aut
700	1	a Martinez-Casas, Isidrou Servicio de Cirugía General, Unidad de Cirugía de Urgencias, Hospital Universitario Virgen del Rocío, Seville, Spain4 aut
700	1	a Cao, Yang,c Associate Professor,d 1972-u Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Clinical Epidemiology and Biostatistics4 aut0 (Swepub:oru)yco
700	1	a Walsh, Thomas N.u Royal College of Surgeons in Ireland Medical University, Busaiteen, Bahrain4 aut
700	1	a Bass, Gary Alan,d 1979-u Örebro universitet,Institutionen för medicinska vetenskaper,Division of Trauma and Emergency Surgery, Örebro University Hospital, Örebro, Sweden; Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA; Center for Perioperative Outcomes Research and Transformation (CPORT), University of Pennsylvania, Philadelphia, USA; Leonard Davis Institute of Health Economics (LDI), University of Pennsylvania, Philadelphia, USA4 aut0 (Swepub:oru)gbs
700	1	a Mohseni, Shahin,d 1978-u Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Division of Trauma and Emergency Surgery, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)snmi
700	1	a Ahl Hulme, Rebecka4 aut
700	1	a Biloslavo, Alan4 aut
700	1	a Kurihara, Hayato4 aut
700	1	a Pereira, Jorge4 aut
700	1	a Pourlotfi, Arvid4 aut
700	1	a Ryan, Éanna J.4 aut
700	1	a Louri, Nayef4 aut
700	1	a Nedham, Fatema4 aut
700	1	a Walsh, Thomas Noel4 aut
700	1	a Hashem, Jamal4 aut
700	1	a Corbally, Martin4 aut
700	1	a Farhan, Abeer4 aut
700	1	a Al Hamad, Hamad4 aut
700	1	a Elhennawy, Rawan4 aut
700	1	a AlKooheji, Mariam4 aut
700	1	a AlYusuf, Manar4 aut
700	1	a Aknouche, Wissal4 aut
700	1	a Zeidan, Anas A.4 aut
700	1	a Alsaffar, Yusuf S.4 aut
700	1	a Lipping, Edgar4 aut
700	1	a Talving, Peep4 aut
700	1	a Saar, Sten4 aut
700	1	a Graumann, Katrina4 aut
700	1	a Kibuspuu, Liis4 aut
700	1	a Harkov, Eduard4 aut
700	1	a Aaltonen, Gisele4 aut
700	1	a Sillman, Iines S.4 aut
700	1	a Haapanen, Sami4 aut
700	1	a Lampela, Hanna4 aut
700	1	a Sammalkorpi, Henna4 aut
700	1	a Eskola, Sofia4 aut
700	1	a Laakso, Altti4 aut
700	1	a Back, Johan4 aut
700	1	a Kettunen, Ulla4 aut
700	1	a Nummi, Antti M.4 aut
700	1	a Szwedyc, Anika4 aut
700	1	a Nykänen, Taina4 aut
700	1	a Rantala, Rolle4 aut
700	1	a Mäkäräinen-Uhlbäck, Elisa J.4 aut
700	1	a Meriläinen, Sanna A.4 aut
700	1	a Huhta, Heikki I.4 aut
700	1	a Rintala, Jukka M.J.4 aut
700	1	a Laitakari, Kirsi E.M.4 aut
700	1	a Lietzen, Elina4 aut
700	1	a Salminen, Paulina4 aut
700	1	a Rapola, Risto K.A.4 aut
700	1	a Zangouri, Vahid4 aut
700	1	a Karami, Mohammad Y.4 aut
700	1	a Tahmasebi, Sedigheh4 aut
700	1	a Akrami, Majid4 aut
700	1	a Golchini, Alireza4 aut
700	1	a Bahrami, Faranak4 aut
700	1	a Johnston, Sean M.4 aut
700	1	a Lim, Sean T.4 aut
700	1	a Ahonkhai, Irele Ifijeh4 aut
700	1	a Eltagani, Eltahir4 aut
700	1	a Ryan, Odhran K.4 aut
700	1	a O’Driscoll-Collins, Ailbhe4 aut
700	1	a O’Neill, Aine4 aut
700	1	a Penny, Zakiya4 aut
700	1	a Kelly, Orlaith4 aut
700	1	a Cullinane, Carolyn4 aut
700	1	a Reynolds, Ian4 aut
700	1	a Heneghan, Helen4 aut
700	1	a Martin, Sean4 aut
700	1	a Winter, Des4 aut
700	1	a Davey, Matthew4 aut
700	1	a Alkhattab, Maha4 aut
700	1	a Lowery, Aoife J.4 aut
700	1	a Kerin, Michael J.4 aut
700	1	a Hogan, Aisling M.4 aut
700	1	a Davey, Martin S.4 aut
700	1	a Oh, Ke En4 aut
700	1	a Kabir, Syed Mohammad Umar4 aut
700	1	a Huan, Huilun4 aut
700	1	a Aziz, Charlotte4 aut
700	1	a Sugrue, Michael4 aut
700	1	a Ryan, Jessica M.4 aut
700	1	a Connelly, Tara M.4 aut
700	1	a Alhazmi, Mohammad4 aut
700	1	a Al-Mukhaizeem, Youssef4 aut
700	1	a Cooke, Fiachra4 aut
700	1	a Neary, Peter M.4 aut
700	1	a Hill, Arnold D.K.4 aut
700	1	a Boland, Michael R.4 aut
700	1	a Lloyd, Angus J.4 aut
700	1	a Fallon, Frances4 aut
700	1	a Cleere, Eoin F.4 aut
700	1	a Toale, James4 aut
700	1	a Boland, Patrick A.4 aut
700	1	a Devine, Michael4 aut
700	1	a Keady, Conor4 aut
700	1	a Caragounis, Eva Corinau Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery4 aut0 (Swepub:gu)xcarae
710	2	a Örebro universitetb Institutionen för medicinska vetenskaper4 org
773	0	t European Journal of Trauma and Emergency Surgeryd : Springer Science and Business Media LLCg 49, s. 57-67q 49<57-67x 1863-9933x 1615-3146x 1863-9941
856	4	u https://doi.org/10.1007/s00068-022-02149-wy Fulltext
856	4 8	u https://gup.ub.gu.se/publication/331761
856	4 8	u https://doi.org/10.1007/s00068-022-02149-w
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-103312
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:151680339

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Av författaren/redakt...: Forssten, Maximi ...; Kaplan, Lewis J.; Tolonen, Matti; Martinez-Casas, ...; Cao, Yang, Assoc ...; Walsh, Thomas N.; visa fler...; Bass, Gary Alan, ...; Mohseni, Shahin, ...; Ahl Hulme, Rebec ...; Biloslavo, Alan; Kurihara, Hayato; Pereira, Jorge; Pourlotfi, Arvid; Ryan, Éanna J.; Louri, Nayef; Nedham, Fatema; Walsh, Thomas No ...; Hashem, Jamal; Corbally, Martin; Farhan, Abeer; Al Hamad, Hamad; Elhennawy, Rawan; AlKooheji, Maria ...; AlYusuf, Manar; Aknouche, Wissal; Zeidan, Anas A.; Alsaffar, Yusuf ...; Lipping, Edgar; Talving, Peep; Saar, Sten; Graumann, Katrin ...; Kibuspuu, Liis; Harkov, Eduard; Aaltonen, Gisele; Sillman, Iines S ...; Haapanen, Sami; Lampela, Hanna; Sammalkorpi, Hen ...; Eskola, Sofia; Laakso, Altti; Back, Johan; Kettunen, Ulla; Nummi, Antti M.; Szwedyc, Anika; Nykänen, Taina; Rantala, Rolle; Mäkäräinen-Uhlbä ...; Meriläinen, Sann ...; Huhta, Heikki I.; Rintala, Jukka M ...; Laitakari, Kirsi ...; Lietzen, Elina; Salminen, Paulin ...; Rapola, Risto K. ...; Zangouri, Vahid; Karami, Mohammad ...; Tahmasebi, Sedig ...; Akrami, Majid; Golchini, Alirez ...; Bahrami, Faranak; Johnston, Sean M ...; Lim, Sean T.; Ahonkhai, Irele ...; Eltagani, Eltahi ...; Ryan, Odhran K.; O’Driscoll-Colli ...; O’Neill, Aine; Penny, Zakiya; Kelly, Orlaith; Cullinane, Carol ...; Reynolds, Ian; Heneghan, Helen; Martin, Sean; Winter, Des; Davey, Matthew; Alkhattab, Maha; Lowery, Aoife J.; Kerin, Michael J ...; Hogan, Aisling M ...; Davey, Martin S.; Oh, Ke En; Kabir, Syed Moha ...; Huan, Huilun; Aziz, Charlotte; Sugrue, Michael; Ryan, Jessica M.; Connelly, Tara M ...; Alhazmi, Mohamma ...; Al-Mukhaizeem, Y ...; Cooke, Fiachra; Neary, Peter M.; Hill, Arnold D.K ...; Boland, Michael ...; Lloyd, Angus J.; Fallon, Frances; Cleere, Eoin F.; Toale, James; Boland, Patrick ...; Devine, Michael; Keady, Conor; Caragounis, Eva ...; visa färre...

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