Greater male than female variability in regional brain structure across the lifespan

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Fältnamn	Indikatorer	Metadata
000		09501naa a2202281 4500
001		oai:DiVA.org:umu-176501
003		SwePub
008		201111s2022 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:144962696
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1765012 URI
024	7	a https://doi.org/10.1002/hbm.252042 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1449626962 URI
040		a (SwePub)umud (SwePub)ki
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Wierenga, Lara M.4 aut
245	1 0	a Greater male than female variability in regional brain structure across the lifespan
264		c 2020-10-12
264	1	b John Wiley & Sons,c 2022
338		a electronic2 rdacarrier
520		a For many traits, males show greater variability than females, with possible implications for understanding sex differences in health and disease. Here, the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Consortium presents the largest-ever mega-analysis of sex differences in variability of brain structure, based on international data spanning nine decades of life. Subcortical volumes, cortical surface area and cortical thickness were assessed in MRI data of 16,683 healthy individuals 1-90 years old (47% females). We observed significant patterns of greater male than female between-subject variance for all subcortical volumetric measures, all cortical surface area measures, and 60% of cortical thickness measures. This pattern was stable across the lifespan for 50% of the subcortical structures, 70% of the regional area measures, and nearly all regions for thickness. Our findings that these sex differences are present in childhood implicate early life genetic or gene-environment interaction mechanisms. The findings highlight the importance of individual differences within the sexes, that may underpin sex-specific vulnerability to disorders.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng
700	1	a Doucet, Gaelle E.4 aut
700	1	a Dima, Danaiu Karolinska Institutet4 aut
700	1	a Agartz, Ingridu Karolinska Institutet4 aut
700	1	a Aghajani, Moji4 aut
700	1	a Akudjedu, Theophilus N.4 aut
700	1	a Albajes-Eizagirre, Anton4 aut
700	1	a Alnaes, Dag4 aut
700	1	a Alpert, Kathryn, I4 aut
700	1	a Andreassen, Ole A.4 aut
700	1	a Anticevic, Alan4 aut
700	1	a Asherson, Philip4 aut
700	1	a Banaschewski, Tobias4 aut
700	1	a Bargallo, Nuria4 aut
700	1	a Baumeister, Sarah4 aut
700	1	a Baur-Streubel, Ramona4 aut
700	1	a Bertolino, Alessandro4 aut
700	1	a Bonvino, Aurora4 aut
700	1	a Boomsma, Dorret, I4 aut
700	1	a Borgwardt, Stefan4 aut
700	1	a Bourque, Josiane4 aut
700	1	a den Braber, Anouk4 aut
700	1	a Brandeis, Daniel4 aut
700	1	a Breier, Alan4 aut
700	1	a Brodaty, Henry4 aut
700	1	a Brouwer, Rachel M.4 aut
700	1	a Buitelaar, Jan K.4 aut
700	1	a Busatto, Geraldo F.4 aut
700	1	a Calhoun, Vince D.4 aut
700	1	a Canales-Rodriguez, Erick J.4 aut
700	1	a Cannon, Dara M.4 aut
700	1	a Caseras, Xavier4 aut
700	1	a Castellanos, Francisco X.4 aut
700	1	a Chaim-Avancini, Tiffany M.4 aut
700	1	a Ching, Christopher R. K.4 aut
700	1	a Clark, Vincent P.4 aut
700	1	a Conrod, Patricia J.4 aut
700	1	a Conzelmann, Annette4 aut
700	1	a Crivello, Fabrice4 aut
700	1	a Davey, Christopher G.4 aut
700	1	a Dickie, Erin W.4 aut
700	1	a Ehrlich, Stefan4 aut
700	1	a Van't Ent, Dennis4 aut
700	1	a Fisher, Simon E.4 aut
700	1	a Fouche, Jean-Paul4 aut
700	1	a Franke, Barbara4 aut
700	1	a Fuentes-Claramonte, Paola4 aut
700	1	a de Geus, Eco J. C.u Karolinska Institutet4 aut
700	1	a Di Giorgio, Annabella4 aut
700	1	a Glahn, David C.4 aut
700	1	a Gotlib, Ian H.4 aut
700	1	a Grabe, Hans J.4 aut
700	1	a Gruber, Oliver4 aut
700	1	a Gruner, Patricia4 aut
700	1	a Gur, Raquel E.4 aut
700	1	a Gur, Ruben C.4 aut
700	1	a Gurholt, Tiril P.4 aut
700	1	a de Haan, Lieuwe4 aut
700	1	a Haatveit, Beathe4 aut
700	1	a Harrison, Ben J.4 aut
700	1	a Hartman, Catharina A.4 aut
700	1	a Hatton, Sean N.4 aut
700	1	a Heslenfeld, Dirk J.4 aut
700	1	a van den Heuvel, Odile A.4 aut
700	1	a Hickie, Ian B.4 aut
700	1	a Hoekstra, Pieter J.4 aut
700	1	a Hohmann, Sarah4 aut
700	1	a Holmes, Avram J.4 aut
700	1	a Hoogman, Martine4 aut
700	1	a Hosten, Norbert4 aut
700	1	a Howells, Fleur M.4 aut
700	1	a Pol, Hilleke E. Hulshoff4 aut
700	1	a Huyser, Chaim4 aut
700	1	a Jahanshad, Neda4 aut
700	1	a James, Anthony C.4 aut
700	1	a Jiang, Jiyangu Karolinska Institutet4 aut
700	1	a Jonsson, Erik G.4 aut
700	1	a Joska, John A.4 aut
700	1	a Kalnin, Andrew J.4 aut
700	1	a Klein, Marieke4 aut
700	1	a Koenders, Laura4 aut
700	1	a Kolskar, Knut K.4 aut
700	1	a Kramer, Bernd4 aut
700	1	a Kuntsi, Jonna4 aut
700	1	a Lagopoulos, Jim4 aut
700	1	a Lazaro, Luisa4 aut
700	1	a Lebedeva, Irina S.4 aut
700	1	a Lee, Phil H.4 aut
700	1	a Lochner, Christine4 aut
700	1	a Machielsen, Marise W. J.4 aut
700	1	a Maingault, Sophie4 aut
700	1	a Martin, Nicholas G.4 aut
700	1	a Martinez-Zalacain, Ignacio4 aut
700	1	a Mataix-Cols, David4 aut
700	1	a Mazoyer, Bernard4 aut
700	1	a McDonald, Brenna C.4 aut
700	1	a McDonald, Colm4 aut
700	1	a McIntosh, Andrew M.4 aut
700	1	a McMahon, Katie L.4 aut
700	1	a McPhilemy, Genevieve4 aut
700	1	a van der Meer, Dennis4 aut
700	1	a Menchon, Jose M.4 aut
700	1	a Naaijen, Jilly4 aut
700	1	a Nyberg, Lars,d 1966-u Umeå universitet,Diagnostisk radiologi,Institutionen för integrativ medicinsk biologi (IMB)4 aut0 (Swepub:umu)lany0001
700	1	a Oosterlaan, Jaap4 aut
700	1	a Paloyelis, Yannis4 aut
700	1	a Pauli, Paul4 aut
700	1	a Pergola, Giulio4 aut
700	1	a Pomarol-Clotet, Edith4 aut
700	1	a Portella, Maria J.4 aut
700	1	a Radua, Joaquim4 aut
700	1	a Reif, Andreas4 aut
700	1	a Richard, Genevieve4 aut
700	1	a Roffman, Joshua L.4 aut
700	1	a Rosa, Pedro G. P.4 aut
700	1	a Sacchet, Matthew D.4 aut
700	1	a Sachdev, Perminder S.4 aut
700	1	a Salvador, Raymond4 aut
700	1	a Sarro, Salvador4 aut
700	1	a Satterthwaite, Theodore D.4 aut
700	1	a Saykin, Andrew J.4 aut
700	1	a Serpa, Mauricio H.4 aut
700	1	a Sim, Kang4 aut
700	1	a Simmons, Andrew4 aut
700	1	a Smoller, Jordan W.4 aut
700	1	a Sommer, Iris E.4 aut
700	1	a Soriano-Mas, Carles4 aut
700	1	a Stein, Dan J.4 aut
700	1	a Strike, Lachlan T.4 aut
700	1	a Szeszko, Philip R.4 aut
700	1	a Temmingh, Henk S.4 aut
700	1	a Thomopoulos, Sophia, I4 aut
700	1	a Tomyshev, Alexander S.4 aut
700	1	a Trollor, Julian N.4 aut
700	1	a Uhlmann, Anne4 aut
700	1	a Veer, Ilya M.4 aut
700	1	a Veltman, Dick J.4 aut
700	1	a Voineskos, Aristotle4 aut
700	1	a Volzke, Henry4 aut
700	1	a Walter, Henrik4 aut
700	1	a Wang, Lei4 aut
700	1	a Wang, Yang4 aut
700	1	a Weber, Bernd4 aut
700	1	a Wen, Wei4 aut
700	1	a West, John D.4 aut
700	1	a Westlye, Lars T.4 aut
700	1	a Whalley, Heather C.4 aut
700	1	a Williams, Steven C. R.4 aut
700	1	a Wittfeld, Katharina4 aut
700	1	a Wolf, Daniel H.4 aut
700	1	a Wright, Margaret J.4 aut
700	1	a Yoncheva, Yuliya N.4 aut
700	1	a Zanetti, Marcus, V4 aut
700	1	a Ziegler, Georg C.4 aut
700	1	a de Zubicaray, Greig, I4 aut
700	1	a Thompson, Paul M.4 aut
700	1	a Crone, Eveline A.4 aut
700	1	a Frangou, Sophia4 aut
700	1	a Tamnes, Christian K.4 aut
710	2	a Karolinska Institutetb Diagnostisk radiologi4 org
773	0	t Human Brain Mappingd : John Wiley & Sonsg 43:1, s. 470-499q 43:1<470-499x 1065-9471x 1097-0193
856	4	u https://doi.org/10.1002/hbm.25204y Fulltext
856	4	u https://umu.diva-portal.org/smash/get/diva2:1500107/FULLTEXT02.pdfx primaryx Raw objecty fulltext:print
856	4	u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hbm.25204
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-176501
856	4 8	u https://doi.org/10.1002/hbm.25204
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:144962696

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Av författaren/redakt...: Wierenga, Lara M ...; Doucet, Gaelle E ...; Dima, Danai; Agartz, Ingrid; Aghajani, Moji; Akudjedu, Theoph ...; visa fler...; Albajes-Eizagirr ...; Alnaes, Dag; Alpert, Kathryn, ...; Andreassen, Ole ...; Anticevic, Alan; Asherson, Philip; Banaschewski, To ...; Bargallo, Nuria; Baumeister, Sara ...; Baur-Streubel, R ...; Bertolino, Aless ...; Bonvino, Aurora; Boomsma, Dorret, ...; Borgwardt, Stefa ...; Bourque, Josiane; den Braber, Anou ...; Brandeis, Daniel; Breier, Alan; Brodaty, Henry; Brouwer, Rachel ...; Buitelaar, Jan K ...; Busatto, Geraldo ...; Calhoun, Vince D ...; Canales-Rodrigue ...; Cannon, Dara M.; Caseras, Xavier; Castellanos, Fra ...; Chaim-Avancini, ...; Ching, Christoph ...; Clark, Vincent P ...; Conrod, Patricia ...; Conzelmann, Anne ...; Crivello, Fabric ...; Davey, Christoph ...; Dickie, Erin W.; Ehrlich, Stefan; Van't Ent, Denni ...; Fisher, Simon E.; Fouche, Jean-Pau ...; Franke, Barbara; Fuentes-Claramon ...; de Geus, Eco J. ...; Di Giorgio, Anna ...; Glahn, David C.; Gotlib, Ian H.; Grabe, Hans J.; Gruber, Oliver; Gruner, Patricia; Gur, Raquel E.; Gur, Ruben C.; Gurholt, Tiril P ...; de Haan, Lieuwe; Haatveit, Beathe; Harrison, Ben J.; Hartman, Cathari ...; Hatton, Sean N.; Heslenfeld, Dirk ...; van den Heuvel, ...; Hickie, Ian B.; Hoekstra, Pieter ...; Hohmann, Sarah; Holmes, Avram J.; Hoogman, Martine; Hosten, Norbert; Howells, Fleur M ...; Pol, Hilleke E. ...; Huyser, Chaim; Jahanshad, Neda; James, Anthony C ...; Jiang, Jiyang; Jonsson, Erik G.; Joska, John A.; Kalnin, Andrew J ...; Klein, Marieke; Koenders, Laura; Kolskar, Knut K.; Kramer, Bernd; Kuntsi, Jonna; Lagopoulos, Jim; Lazaro, Luisa; Lebedeva, Irina ...; Lee, Phil H.; Lochner, Christi ...; Machielsen, Mari ...; Maingault, Sophi ...; Martin, Nicholas ...; Martinez-Zalacai ...; Mataix-Cols, Dav ...; Mazoyer, Bernard; McDonald, Brenna ...; McDonald, Colm; McIntosh, Andrew ...; McMahon, Katie L ...; McPhilemy, Genev ...; van der Meer, De ...; Menchon, Jose M.; Naaijen, Jilly; Nyberg, Lars, 19 ...; Oosterlaan, Jaap; Paloyelis, Yanni ...; Pauli, Paul; Pergola, Giulio; Pomarol-Clotet, ...; Portella, Maria ...; Radua, Joaquim; Reif, Andreas; Richard, Genevie ...; Roffman, Joshua ...; Rosa, Pedro G. P ...; Sacchet, Matthew ...; Sachdev, Permind ...; Salvador, Raymon ...; Sarro, Salvador; Satterthwaite, T ...; Saykin, Andrew J ...; Serpa, Mauricio ...; Sim, Kang; Simmons, Andrew; Smoller, Jordan ...; Sommer, Iris E.; Soriano-Mas, Car ...; Stein, Dan J.; Strike, Lachlan ...; Szeszko, Philip ...; Temmingh, Henk S ...; Thomopoulos, Sop ...; Tomyshev, Alexan ...; Trollor, Julian ...; Uhlmann, Anne; Veer, Ilya M.; Veltman, Dick J.; Voineskos, Arist ...; Volzke, Henry; Walter, Henrik; Wang, Lei; Wang, Yang; Weber, Bernd; Wen, Wei; West, John D.; Westlye, Lars T.; Whalley, Heather ...; Williams, Steven ...; Wittfeld, Kathar ...; Wolf, Daniel H.; Wright, Margaret ...; Yoncheva, Yuliya ...; Zanetti, Marcus, ...; Ziegler, Georg C ...; de Zubicaray, Gr ...; Thompson, Paul M ...; Crone, Eveline A ...; Frangou, Sophia; Tamnes, Christia ...; visa färre...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Medicinska och f ...; och Neurovetenskaper

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Radiologi och bi ...

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Av lärosätet: Umeå universitet; Karolinska Institutet

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