Search: (WFRF:(Kahnoski Richard J)) pers:(Weinstein Stephanie) pers:(Machiela Mitchell J) pers:(Lipworth Loren) >
Genome-wide associa...
Genome-wide association study identifies multiple risk loci for renal cell carcinoma.
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Scelo, Ghislaine (author)
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Purdue, Mark P (author)
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Brown, Kevin M (author)
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show more...
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Johansson, Mattias (author)
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Wang, Zhaoming (author)
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Eckel-Passow, Jeanette E (author)
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Ye, Yuanqing (author)
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Hofmann, Jonathan N (author)
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Choi, Jiyeon (author)
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Foll, Matthieu (author)
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Gaborieau, Valerie (author)
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Machiela, Mitchell J (author)
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Colli, Leandro M (author)
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Li, Peng (author)
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Sampson, Joshua N (author)
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Abedi-Ardekani, Behnoush (author)
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Besse, Celine (author)
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Blanche, Helene (author)
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Boland, Anne (author)
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Burdette, Laurie (author)
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Chabrier, Amelie (author)
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Durand, Geoffroy (author)
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Le Calvez-Kelm, Florence (author)
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Prokhortchouk, Egor (author)
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Robinot, Nivonirina (author)
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Skryabin, Konstantin G (author)
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Wozniak, Magdalena B (author)
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Yeager, Meredith (author)
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Basta-Jovanovic, Gordana (author)
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Dzamic, Zoran (author)
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Foretova, Lenka (author)
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Holcatova, Ivana (author)
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Janout, Vladimir (author)
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Mates, Dana (author)
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Mukeriya, Anush (author)
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Rascu, Stefan (author)
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Zaridze, David (author)
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Bencko, Vladimir (author)
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- Cybulski, Cezary (author)
- Karolinska Institutet
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Fabianova, Eleonora (author)
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Jinga, Viorel (author)
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Lissowska, Jolanta (author)
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Lubinski, Jan (author)
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Navratilova, Marie (author)
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Rudnai, Peter (author)
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Szeszenia-Dabrowska, Neonila (author)
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Benhamou, Simone (author)
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Cancel-Tassin, Geraldine (author)
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Cussenot, Olivier (author)
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Baglietto, Laura (author)
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Boeing, Heiner (author)
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Khaw, Kay-Tee (author)
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- Weiderpass, Elisabete (author)
- Karolinska Institutet
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- Ljungberg, Börje (author)
- Umeå universitet,Urologi och andrologi
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- Sitaram, Raviprakash T. (author)
- Umeå universitet,Urologi och andrologi
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Bruinsma, Fiona (author)
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Jordan, Susan J (author)
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Severi, Gianluca (author)
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Winship, Ingrid (author)
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Hveem, Kristian (author)
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Vatten, Lars J (author)
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Fletcher, Tony (author)
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Koppova, Kvetoslava (author)
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- Larsson, Susanna C (author)
- Uppsala universitet,Ortopedi
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- Wolk, Alicja (author)
- Karolinska Institutet,Uppsala universitet,Ortopedi
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Banks, Rosamonde E (author)
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Selby, Peter J (author)
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Easton, Douglas F (author)
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Pharoah, Paul (author)
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Andreotti, Gabriella (author)
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Freeman, Laura E Beane (author)
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Koutros, Stella (author)
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Albanes, Demetrius (author)
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Männistö, Satu (author)
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Weinstein, Stephanie (author)
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Clark, Peter E (author)
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Edwards, Todd L (author)
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Lipworth, Loren (author)
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Gapstur, Susan M (author)
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Stevens, Victoria L (author)
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Carol, Hallie (author)
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Freedman, Matthew L (author)
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Pomerantz, Mark M (author)
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Cho, Eunyoung (author)
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Kraft, Peter (author)
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Preston, Mark A (author)
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Wilson, Kathryn M (author)
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Michael Gaziano, J (author)
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Sesso, Howard D (author)
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Black, Amanda (author)
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Freedman, Neal D (author)
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Huang, Wen-Yi (author)
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Anema, John G (author)
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Kahnoski, Richard J (author)
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Lane, Brian R (author)
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Noyes, Sabrina L (author)
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Petillo, David (author)
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Teh, Bin Tean (author)
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Peters, Ulrike (author)
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White, Emily (author)
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Anderson, Garnet L (author)
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Johnson, Lisa (author)
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Luo, Juhua (author)
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Buring, Julie (author)
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Lee, I-Min (author)
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Chow, Wong-Ho (author)
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Moore, Lee E (author)
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Wood, Christopher (author)
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Eisen, Timothy (author)
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Henrion, Marc (author)
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Larkin, James (author)
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Barman, Poulami (author)
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Leibovich, Bradley C (author)
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Choueiri, Toni K (author)
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Mark Lathrop, G (author)
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Rothman, Nathaniel (author)
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Deleuze, Jean-Francois (author)
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McKay, James D (author)
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Parker, Alexander S (author)
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Wu, Xifeng (author)
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Houlston, Richard S (author)
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Brennan, Paul (author)
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Chanock, Stephen J (author)
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(creator_code:org_t)
- 2017-06-09
- 2017
- English.
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In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 8
- Related links:
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https://www.nature.c...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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https://urn.kb.se/re...
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Abstract
Subject headings
Close
- Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing scans, totalling 10,784 cases and 20,406 controls of European ancestry. Twenty-four loci were tested in an additional 3,182 cases and 6,301 controls. We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10-10), 3p22.1 (rs67311347, P=2.5 × 10-8), 3q26.2 (rs10936602, P=8.8 × 10-9), 8p21.3 (rs2241261, P=5.8 × 10-9), 10q24.33-q25.1 (rs11813268, P=3.9 × 10-8), 11q22.3 (rs74911261, P=2.1 × 10-10) and 14q24.2 (rs4903064, P=2.2 × 10-24). Expression quantitative trait analyses suggest plausible candidate genes at these regions that may contribute to RCC susceptibility.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Scelo, Ghislaine
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Purdue, Mark P
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Brown, Kevin M
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Johansson, Matti ...
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Wang, Zhaoming
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Eckel-Passow, Je ...
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show more...
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Ye, Yuanqing
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Hofmann, Jonatha ...
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Choi, Jiyeon
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Foll, Matthieu
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Gaborieau, Valer ...
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Machiela, Mitche ...
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Colli, Leandro M
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Li, Peng
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Sampson, Joshua ...
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Abedi-Ardekani, ...
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Besse, Celine
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Blanche, Helene
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Boland, Anne
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Burdette, Laurie
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Chabrier, Amelie
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Durand, Geoffroy
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Le Calvez-Kelm, ...
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Prokhortchouk, E ...
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Robinot, Nivonir ...
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Skryabin, Konsta ...
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Wozniak, Magdale ...
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Yeager, Meredith
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Basta-Jovanovic, ...
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Dzamic, Zoran
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Foretova, Lenka
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Holcatova, Ivana
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Janout, Vladimir
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Mates, Dana
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Mukeriya, Anush
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Rascu, Stefan
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Zaridze, David
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Bencko, Vladimir
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Cybulski, Cezary
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Fabianova, Eleon ...
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Jinga, Viorel
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Lissowska, Jolan ...
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Lubinski, Jan
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Navratilova, Mar ...
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Rudnai, Peter
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Szeszenia-Dabrow ...
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Benhamou, Simone
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Cancel-Tassin, G ...
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Cussenot, Olivie ...
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Baglietto, Laura
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Boeing, Heiner
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Khaw, Kay-Tee
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Weiderpass, Elis ...
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Ljungberg, Börje
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Sitaram, Ravipra ...
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Bruinsma, Fiona
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Jordan, Susan J
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Severi, Gianluca
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Winship, Ingrid
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Hveem, Kristian
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Vatten, Lars J
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Fletcher, Tony
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Koppova, Kvetosl ...
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Larsson, Susanna ...
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Wolk, Alicja
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Banks, Rosamonde ...
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Selby, Peter J
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Easton, Douglas ...
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Pharoah, Paul
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Andreotti, Gabri ...
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Freeman, Laura E ...
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Koutros, Stella
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Albanes, Demetri ...
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Männistö, Satu
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Weinstein, Steph ...
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Clark, Peter E
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Edwards, Todd L
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Lipworth, Loren
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Gapstur, Susan M
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Stevens, Victori ...
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Carol, Hallie
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Freedman, Matthe ...
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Pomerantz, Mark ...
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Cho, Eunyoung
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Kraft, Peter
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Preston, Mark A
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Wilson, Kathryn ...
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Michael Gaziano, ...
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Sesso, Howard D
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Black, Amanda
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Freedman, Neal D
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Huang, Wen-Yi
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Anema, John G
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Kahnoski, Richar ...
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Lane, Brian R
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Noyes, Sabrina L
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Petillo, David
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Teh, Bin Tean
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Peters, Ulrike
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White, Emily
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Anderson, Garnet ...
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Johnson, Lisa
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Luo, Juhua
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Buring, Julie
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Lee, I-Min
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Chow, Wong-Ho
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Moore, Lee E
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Wood, Christophe ...
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Eisen, Timothy
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Henrion, Marc
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Larkin, James
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Barman, Poulami
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Leibovich, Bradl ...
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Choueiri, Toni K
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Mark Lathrop, G
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Rothman, Nathani ...
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Deleuze, Jean-Fr ...
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McKay, James D
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Parker, Alexande ...
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Wu, Xifeng
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Houlston, Richar ...
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Brennan, Paul
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Chanock, Stephen ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Urology and Neph ...
- Articles in the publication
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Nature Communica ...
- By the university
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Uppsala University
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Karolinska Institutet
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Umeå University