(WFRF:(Kircher Tilo T J)) pers:(Fullerton Janice M)
Sökning: (WFRF:(Kircher Tilo T J)) pers:(Fullerton Janice M) > Mega-analysis of as...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 06133naa a2201189 4500 | |
| 001 | oai:gup.ub.gu.se/325709 | |
| 003 | SwePub | |
| 008 | 240528s2023 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:152159220 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/3257092 URI |
| 024 | 7 | a https://doi.org/10.1017/S00332917230002232 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1521592202 URI |
| 040 | a (SwePub)gud (SwePub)ki | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a McWhinney, Sean R4 aut |
| 245 | 1 0 | a Mega-analysis of association between obesity and cortical morphology in bipolar disorders: ENIGMA study in 2832 participants. |
| 264 | 1 | c 2023 |
| 520 | a Obesity is highly prevalent and disabling, especially in individuals with severe mental illness including bipolar disorders (BD). The brain is a target organ for both obesity and BD. Yet, we do not understand how cortical brain alterations in BD and obesity interact.We obtained body mass index (BMI) and MRI-derived regional cortical thickness, surface area from 1231 BD and 1601 control individuals from 13 countries within the ENIGMA-BD Working Group. We jointly modeled the statistical effects of BD and BMI on brain structure using mixed effects and tested for interaction and mediation. We also investigated the impact of medications on the BMI-related associations.BMI and BD additively impacted the structure of many of the same brain regions. Both BMI and BD were negatively associated with cortical thickness, but not surface area. In most regions the number of jointly used psychiatric medication classes remained associated with lower cortical thickness when controlling for BMI. In a single region, fusiform gyrus, about a third of the negative association between number of jointly used psychiatric medications and cortical thickness was mediated by association between the number of medications and higher BMI.We confirmed consistent associations between higher BMI and lower cortical thickness, but not surface area, across the cerebral mantle, in regions which were also associated with BD. Higher BMI in people with BD indicated more pronounced brain alterations. BMI is important for understanding the neuroanatomical changes in BD and the effects of psychiatric medications on the brain. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng |
| 700 | 1 | a Abé, Christophu Karolinska Institutet4 aut |
| 700 | 1 | a Alda, Martin4 aut |
| 700 | 1 | a Benedetti, Francesco4 aut |
| 700 | 1 | a Bøen, Erlend4 aut |
| 700 | 1 | a Del Mar Bonnin, Caterina4 aut |
| 700 | 1 | a Borgers, Tiana4 aut |
| 700 | 1 | a Brosch, Katharina4 aut |
| 700 | 1 | a Canales-Rodríguez, Erick J4 aut |
| 700 | 1 | a Cannon, Dara M4 aut |
| 700 | 1 | a Dannlowski, Udo4 aut |
| 700 | 1 | a Diaz-Zuluaga, Ana M4 aut |
| 700 | 1 | a Dietze, Lorielle M F4 aut |
| 700 | 1 | a Elvsåshagen, Torbjørn4 aut |
| 700 | 1 | a Eyler, Lisa T4 aut |
| 700 | 1 | a Fullerton, Janice M4 aut |
| 700 | 1 | a Goikolea, Jose M4 aut |
| 700 | 1 | a Goltermann, Janik4 aut |
| 700 | 1 | a Grotegerd, Dominik4 aut |
| 700 | 1 | a Haarman, Bartholomeus C M4 aut |
| 700 | 1 | a Hahn, Tim4 aut |
| 700 | 1 | a Howells, Fleur M4 aut |
| 700 | 1 | a Ingvar, Martinu Karolinska Institutet4 aut |
| 700 | 1 | a Jahanshad, Neda4 aut |
| 700 | 1 | a Kircher, Tilo T J4 aut |
| 700 | 1 | a Krug, Axel4 aut |
| 700 | 1 | a Kuplicki, Rayus T4 aut |
| 700 | 1 | a Landén, Mikael,d 1966u Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xlandt |
| 700 | 1 | a Lemke, Hannah4 aut |
| 700 | 1 | a Liberg, Benny4 aut |
| 700 | 1 | a Lopez-Jaramillo, Carlos4 aut |
| 700 | 1 | a Malt, Ulrik F4 aut |
| 700 | 1 | a Martyn, Fiona M4 aut |
| 700 | 1 | a Mazza, Elena4 aut |
| 700 | 1 | a McDonald, Colm4 aut |
| 700 | 1 | a McPhilemy, Genevieve4 aut |
| 700 | 1 | a Meier, Sandra4 aut |
| 700 | 1 | a Meinert, Susanne4 aut |
| 700 | 1 | a Meller, Tina4 aut |
| 700 | 1 | a Melloni, Elisa M T4 aut |
| 700 | 1 | a Mitchell, Philip B4 aut |
| 700 | 1 | a Nabulsi, Leila4 aut |
| 700 | 1 | a Nenadic, Igor4 aut |
| 700 | 1 | a Opel, Nils4 aut |
| 700 | 1 | a Ophoff, Roel A4 aut |
| 700 | 1 | a Overs, Bronwyn J4 aut |
| 700 | 1 | a Pfarr, Julia-Katharina4 aut |
| 700 | 1 | a Pineda-Zapata, Julian A4 aut |
| 700 | 1 | a Pomarol-Clotet, Edith4 aut |
| 700 | 1 | a Raduà, Joaquim4 aut |
| 700 | 1 | a Repple, Jonathan4 aut |
| 700 | 1 | a Richter, Maike4 aut |
| 700 | 1 | a Ringwald, Kai G4 aut |
| 700 | 1 | a Roberts, Gloria4 aut |
| 700 | 1 | a Ross, Alex4 aut |
| 700 | 1 | a Salvador, Raymond4 aut |
| 700 | 1 | a Savitz, Jonathan4 aut |
| 700 | 1 | a Schmitt, Simon4 aut |
| 700 | 1 | a Schofield, Peter R4 aut |
| 700 | 1 | a Sim, Kang4 aut |
| 700 | 1 | a Stein, Dan J4 aut |
| 700 | 1 | a Stein, Frederike4 aut |
| 700 | 1 | a Temmingh, Henk S4 aut |
| 700 | 1 | a Thiel, Katharina4 aut |
| 700 | 1 | a Thomopoulos, Sophia I4 aut |
| 700 | 1 | a van Haren, Neeltje E M4 aut |
| 700 | 1 | a Vargas, Cristian4 aut |
| 700 | 1 | a Vieta, Eduard4 aut |
| 700 | 1 | a Vreeker, Annabel4 aut |
| 700 | 1 | a Waltemate, Lena4 aut |
| 700 | 1 | a Yatham, Lakshmi N4 aut |
| 700 | 1 | a Ching, Christopher R K4 aut |
| 700 | 1 | a Andreassen, Ole A4 aut |
| 700 | 1 | a Thompson, Paul M4 aut |
| 700 | 1 | a Hajek, Tomas4 aut |
| 710 | 2 | a Karolinska Institutetb Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi4 org |
| 773 | 0 | t Psychological medicineg 53:14, s. 6743-6753q 53:14<6743-6753x 1469-8978 |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/325709 |
| 856 | 4 8 | u https://doi.org/10.1017/S0033291723000223 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:152159220 |
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- Abé, Christoph
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- Brosch, Katharin ...
- Canales-Rodrígue ...
- Cannon, Dara M
- Dannlowski, Udo
- Diaz-Zuluaga, An ...
- Dietze, Lorielle ...
- Elvsåshagen, Tor ...
- Eyler, Lisa T
- Fullerton, Janic ...
- Goikolea, Jose M
- Goltermann, Jani ...
- Grotegerd, Domin ...
- Haarman, Barthol ...
- Hahn, Tim
- Howells, Fleur M
- Ingvar, Martin
- Jahanshad, Neda
- Kircher, Tilo T ...
- Krug, Axel
- Kuplicki, Rayus ...
- Landén, Mikael, ...
- Lemke, Hannah
- Liberg, Benny
- Lopez-Jaramillo, ...
- Malt, Ulrik F
- Martyn, Fiona M
- Mazza, Elena
- McDonald, Colm
- McPhilemy, Genev ...
- Meier, Sandra
- Meinert, Susanne
- Meller, Tina
- Melloni, Elisa M ...
- Mitchell, Philip ...
- Nabulsi, Leila
- Nenadic, Igor
- Opel, Nils
- Ophoff, Roel A
- Overs, Bronwyn J
- Pfarr, Julia-Kat ...
- Pineda-Zapata, J ...
- Pomarol-Clotet, ...
- Raduà, Joaquim
- Repple, Jonathan
- Richter, Maike
- Ringwald, Kai G
- Roberts, Gloria
- Ross, Alex
- Salvador, Raymon ...
- Savitz, Jonathan
- Schmitt, Simon
- Schofield, Peter ...
- Sim, Kang
- Stein, Dan J
- Stein, Frederike
- Temmingh, Henk S
- Thiel, Katharina
- Thomopoulos, Sop ...
- van Haren, Neelt ...
- Vargas, Cristian
- Vieta, Eduard
- Vreeker, Annabel
- Waltemate, Lena
- Yatham, Lakshmi ...
- Ching, Christoph ...
- Andreassen, Ole ...
- Thompson, Paul M
- Hajek, Tomas
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