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Second internationa...
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine
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- Tobias, Deirdre K (author)
- Harvard Medical School,Harvard T.H. Chan School of Public Health
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- Merino, Jordi (author)
- University of Copenhagen,Massachusetts General Hospital
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- Ahmad, Abrar (author)
- Lund University,Lunds universitet,-lup-obsolete,Forskargrupper vid Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,LUDC (Lund University Diabetes Centre)-lup-obsolete,Lund University Research Groups,Department of Clinical Sciences, Malmö,Faculty of Medicine
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- Aiken, Catherine (author)
- University of Cambridge,Rosie Hospital
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- Benham, Jamie L (author)
- University of Calgary
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- Bodhini, Dhanasekaran (author)
- Madras Diabetes Research Foundation
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- Clark, Amy L (author)
- Saint Louis University School of Medicine
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- Colclough, Kevin (author)
- University of Exeter
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- Corcoy, Rosa (author)
- CIBER Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN),Autonomous University of Barcelona
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- Cromer, Sara J (author)
- Harvard Medical School,Massachusetts General Hospital,Broad Institute
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- Duan, Daisy (author)
- Johns Hopkins University
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- Felton, Jamie L (author)
- Indiana University
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Francis, Ellen C (author)
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Gillard, Pieter (author)
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Gingras, Véronique (author)
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Gaillard, Romy (author)
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Haider, Eram (author)
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Hughes, Alice (author)
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Ikle, Jennifer M (author)
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Jacobsen, Laura M (author)
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Kahkoska, Anna R (author)
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Kettunen, Jarno L T (author)
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Kreienkamp, Raymond J (author)
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Lim, Lee-Ling (author)
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Männistö, Jonna M E (author)
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Massey, Robert (author)
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Mclennan, Niamh-Maire (author)
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Miller, Rachel G (author)
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Morieri, Mario Luca (author)
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Most, Jasper (author)
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Naylor, Rochelle N (author)
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Ozkan, Bige (author)
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Patel, Kashyap Amratlal (author)
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Pilla, Scott J (author)
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Prystupa, Katsiaryna (author)
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Raghavan, Sridharan (author)
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Rooney, Mary R (author)
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Schön, Martin (author)
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Semnani-Azad, Zhila (author)
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Sevilla-Gonzalez, Magdalena (author)
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Svalastoga, Pernille (author)
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Takele, Wubet Worku (author)
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Tam, Claudia Ha-Ting (author)
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Thuesen, Anne Cathrine B (author)
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Tosur, Mustafa (author)
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Wallace, Amelia S (author)
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Wang, Caroline C (author)
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Wong, Jessie J (author)
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Yamamoto, Jennifer M (author)
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Young, Katherine (author)
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Amouyal, Chloé (author)
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Andersen, Mette K (author)
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Bonham, Maxine P (author)
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Chen, Mingling (author)
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Cheng, Feifei (author)
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Chikowore, Tinashe (author)
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Chivers, Sian C (author)
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Clemmensen, Christoffer (author)
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Dabelea, Dana (author)
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Dawed, Adem Y (author)
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Deutsch, Aaron J (author)
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Dickens, Laura T (author)
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DiMeglio, Linda A (author)
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- Dudenhöffer-Pfeifer, Monika (author)
- Lund University,Lunds universitet,-lup-obsolete,Forskargrupper vid Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,LUDC (Lund University Diabetes Centre)-lup-obsolete,Lund University Research Groups,Department of Clinical Sciences, Malmö,Faculty of Medicine
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Evans-Molina, Carmella (author)
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Fernández-Balsells, María Mercè (author)
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- Fitipaldi, Hugo (author)
- Lund University,Lunds universitet,-lup-obsolete,Forskargrupper vid Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,LUDC (Lund University Diabetes Centre)-lup-obsolete,Lund University Research Groups,Department of Clinical Sciences, Malmö,Faculty of Medicine
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Fitzpatrick, Stephanie L (author)
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Gitelman, Stephen E (author)
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Goodarzi, Mark O (author)
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Grieger, Jessica A (author)
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Guasch-Ferré, Marta (author)
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Habibi, Nahal (author)
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Hansen, Torben (author)
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Huang, Chuiguo (author)
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Harris-Kawano, Arianna (author)
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Ismail, Heba M (author)
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Hoag, Benjamin (author)
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Johnson, Randi K (author)
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Jones, Angus G (author)
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Koivula, Robert W (author)
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Leong, Aaron (author)
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Leung, Gloria K W (author)
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Libman, Ingrid M (author)
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Liu, Kai (author)
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Long, S Alice (author)
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Lowe, William L (author)
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Morton, Robert W (author)
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Motala, Ayesha A (author)
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Onengut-Gumuscu, Suna (author)
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Pankow, James S (author)
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Pathirana, Maleesa (author)
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Pazmino, Sofia (author)
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Perez, Dianna (author)
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Petrie, John R (author)
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Powe, Camille E (author)
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Quinteros, Alejandra (author)
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Jain, Rashmi (author)
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Ray, Debashree (author)
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Ried-Larsen, Mathias (author)
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Saeed, Zeb (author)
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Santhakumar, Vanessa (author)
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Kanbour, Sarah (author)
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Sarkar, Sudipa (author)
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Monaco, Gabriela S F (author)
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Scholtens, Denise M (author)
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Selvin, Elizabeth (author)
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Sheu, Wayne Huey-Herng (author)
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Speake, Cate (author)
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Stanislawski, Maggie A (author)
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Steenackers, Nele (author)
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Steck, Andrea K (author)
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Stefan, Norbert (author)
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Støy, Julie (author)
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Taylor, Rachael (author)
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Tye, Sok Cin (author)
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Ukke, Gebresilasea Gendisha (author)
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Urazbayeva, Marzhan (author)
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Van der Schueren, Bart (author)
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Vatier, Camille (author)
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Wentworth, John M (author)
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Hannah, Wesley (author)
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White, Sara L (author)
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Yu, Gechang (author)
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Zhang, Yingchai (author)
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Zhou, Shao J (author)
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Beltrand, Jacques (author)
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Polak, Michel (author)
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Aukrust, Ingvild (author)
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de Franco, Elisa (author)
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Flanagan, Sarah E (author)
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Maloney, Kristin A (author)
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McGovern, Andrew (author)
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Molnes, Janne (author)
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Nakabuye, Mariam (author)
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Njølstad, Pål Rasmus (author)
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- Pomares-Millan, Hugo (author)
- Lund University,Lunds universitet,-lup-obsolete,Forskargrupper vid Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,LUDC (Lund University Diabetes Centre)-lup-obsolete,Lund University Research Groups,Department of Clinical Sciences, Malmö,Faculty of Medicine,Dartmouth College
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Provenzano, Michele (author)
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Saint-Martin, Cécile (author)
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Zhang, Cuilin (author)
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Zhu, Yeyi (author)
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Auh, Sungyoung (author)
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de Souza, Russell (author)
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Fawcett, Andrea J (author)
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Gruber, Chandra (author)
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Mekonnen, Eskedar Getie (author)
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Mixter, Emily (author)
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Sherifali, Diana (author)
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Eckel, Robert H (author)
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Nolan, John J (author)
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Philipson, Louis H (author)
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Brown, Rebecca J (author)
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Billings, Liana K (author)
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Boyle, Kristen (author)
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Costacou, Tina (author)
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Dennis, John M (author)
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Florez, Jose C (author)
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Gloyn, Anna L (author)
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- Gomez, Maria F (author)
- Lund University,Lunds universitet,-lup-obsolete,Forskargrupper vid Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,LUDC (Lund University Diabetes Centre)-lup-obsolete,Lund University Research Groups,Department of Clinical Sciences, Malmö,Faculty of Medicine,Aarhus University
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Gottlieb, Peter A (author)
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Greeley, Siri Atma W (author)
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Griffin, Kurt (author)
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Hattersley, Andrew T (author)
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Hirsch, Irl B (author)
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Hivert, Marie-France (author)
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Hood, Korey K (author)
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Josefson, Jami L (author)
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Kwak, Soo Heon (author)
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Laffel, Lori M (author)
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Lim, Siew S (author)
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Loos, Ruth J F (author)
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Ma, Ronald C W (author)
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Mathieu, Chantal (author)
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Mathioudakis, Nestoras (author)
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Meigs, James B (author)
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Misra, Shivani (author)
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Mohan, Viswanathan (author)
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Murphy, Rinki (author)
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Oram, Richard (author)
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Owen, Katharine R (author)
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Ozanne, Susan E (author)
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Pearson, Ewan R (author)
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Perng, Wei (author)
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Pollin, Toni I (author)
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Pop-Busui, Rodica (author)
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Pratley, Richard E (author)
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Redman, Leanne M (author)
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Redondo, Maria J (author)
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Reynolds, Rebecca M (author)
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Semple, Robert K (author)
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Sherr, Jennifer L (author)
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Sims, Emily K (author)
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Sweeting, Arianne (author)
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Tuomi, Tiinamaija (author)
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Udler, Miriam S (author)
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Vesco, Kimberly K (author)
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Vilsbøll, Tina (author)
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Wagner, Robert (author)
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Rich, Stephen S (author)
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- Franks, Paul W (author)
- Lund University,Lunds universitet,-lup-obsolete,Forskargrupper vid Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,LUDC (Lund University Diabetes Centre)-lup-obsolete,Lund University Research Groups,Department of Clinical Sciences, Malmö,Faculty of Medicine,Harvard T.H. Chan School of Public Health,University of Oxford
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Harvard Medical School Harvard TH. Chan School of Public Health (creator_code:org_t)
- 2023
- 2023
- English 20 s.
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In: Nature Medicine. - 1546-170X. ; 29:10, s. 2438-2457
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Precision medicine is part of the logical evolution of contemporary evidence-based medicine that seeks to reduce errors and optimize outcomes when making medical decisions and health recommendations. Diabetes affects hundreds of millions of people worldwide, many of whom will develop life-threatening complications and die prematurely. Precision medicine can potentially address this enormous problem by accounting for heterogeneity in the etiology, clinical presentation and pathogenesis of common forms of diabetes and risks of complications. This second international consensus report on precision diabetes medicine summarizes the findings from a systematic evidence review across the key pillars of precision medicine (prevention, diagnosis, treatment, prognosis) in four recognized forms of diabetes (monogenic, gestational, type 1, type 2). These reviews address key questions about the translation of precision medicine research into practice. Although not complete, owing to the vast literature on this topic, they revealed opportunities for the immediate or near-term clinical implementation of precision diabetes medicine; furthermore, we expose important gaps in knowledge, focusing on the need to obtain new clinically relevant evidence. Gaps include the need for common standards for clinical readiness, including consideration of cost-effectiveness, health equity, predictive accuracy, liability and accessibility. Key milestones are outlined for the broad clinical implementation of precision diabetes medicine.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- Medical research
- Translational research
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- ref (subject category)
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- By the author/editor
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Tobias, Deirdre ...
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Merino, Jordi
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Ahmad, Abrar
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Aiken, Catherine
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Benham, Jamie L
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Bodhini, Dhanase ...
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show more...
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Clark, Amy L
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Colclough, Kevin
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Corcoy, Rosa
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Cromer, Sara J
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Duan, Daisy
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Felton, Jamie L
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Francis, Ellen C
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Gillard, Pieter
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Gingras, Véroniq ...
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Gaillard, Romy
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Haider, Eram
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Hughes, Alice
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Ikle, Jennifer M
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Jacobsen, Laura ...
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Kahkoska, Anna R
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Kettunen, Jarno ...
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Kreienkamp, Raym ...
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Lim, Lee-Ling
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Männistö, Jonna ...
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Massey, Robert
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Mclennan, Niamh- ...
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Miller, Rachel G
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Morieri, Mario L ...
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Most, Jasper
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Naylor, Rochelle ...
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Ozkan, Bige
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Patel, Kashyap A ...
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Pilla, Scott J
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Prystupa, Katsia ...
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Raghavan, Sridha ...
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Rooney, Mary R
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Schön, Martin
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Semnani-Azad, Zh ...
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Sevilla-Gonzalez ...
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Svalastoga, Pern ...
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Takele, Wubet Wo ...
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Tam, Claudia Ha- ...
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Thuesen, Anne Ca ...
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Tosur, Mustafa
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Wallace, Amelia ...
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Wang, Caroline C
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Wong, Jessie J
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Yamamoto, Jennif ...
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Young, Katherine
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Amouyal, Chloé
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Andersen, Mette ...
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Bonham, Maxine P
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Chen, Mingling
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Cheng, Feifei
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Chikowore, Tinas ...
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Chivers, Sian C
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Clemmensen, Chri ...
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Dabelea, Dana
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Dawed, Adem Y
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Deutsch, Aaron J
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Dickens, Laura T
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DiMeglio, Linda ...
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Dudenhöffer-Pfei ...
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Evans-Molina, Ca ...
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Fernández-Balsel ...
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Fitipaldi, Hugo
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Fitzpatrick, Ste ...
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Gitelman, Stephe ...
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Goodarzi, Mark O
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Grieger, Jessica ...
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Guasch-Ferré, Ma ...
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Habibi, Nahal
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Hansen, Torben
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Huang, Chuiguo
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Harris-Kawano, A ...
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Ismail, Heba M
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Hoag, Benjamin
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Johnson, Randi K
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Jones, Angus G
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Koivula, Robert ...
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Leong, Aaron
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Leung, Gloria K ...
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Libman, Ingrid M
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Liu, Kai
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Long, S Alice
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Lowe, William L
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Morton, Robert W
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Motala, Ayesha A
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Onengut-Gumuscu, ...
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Pankow, James S
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Pathirana, Malee ...
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Pazmino, Sofia
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Perez, Dianna
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Petrie, John R
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Powe, Camille E
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Quinteros, Aleja ...
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Jain, Rashmi
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Ray, Debashree
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Ried-Larsen, Mat ...
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Saeed, Zeb
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Santhakumar, Van ...
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Kanbour, Sarah
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Sarkar, Sudipa
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Monaco, Gabriela ...
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Scholtens, Denis ...
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Selvin, Elizabet ...
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Sheu, Wayne Huey ...
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Speake, Cate
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Stanislawski, Ma ...
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Steenackers, Nel ...
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Steck, Andrea K
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Stefan, Norbert
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Støy, Julie
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Taylor, Rachael
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Tye, Sok Cin
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Ukke, Gebresilas ...
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Urazbayeva, Marz ...
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Van der Schueren ...
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Vatier, Camille
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Wentworth, John ...
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Hannah, Wesley
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White, Sara L
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Yu, Gechang
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Zhang, Yingchai
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Zhou, Shao J
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Beltrand, Jacque ...
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Polak, Michel
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Aukrust, Ingvild
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de Franco, Elisa
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Flanagan, Sarah ...
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Maloney, Kristin ...
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McGovern, Andrew
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Molnes, Janne
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Nakabuye, Mariam
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Njølstad, Pål Ra ...
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Pomares-Millan, ...
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Provenzano, Mich ...
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Saint-Martin, Cé ...
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Zhang, Cuilin
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Zhu, Yeyi
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Auh, Sungyoung
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de Souza, Russel ...
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Fawcett, Andrea ...
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Gruber, Chandra
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Mekonnen, Eskeda ...
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Mixter, Emily
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Sherifali, Diana
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Eckel, Robert H
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Nolan, John J
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Philipson, Louis ...
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Brown, Rebecca J
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Billings, Liana ...
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Boyle, Kristen
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Costacou, Tina
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Dennis, John M
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Florez, Jose C
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Gloyn, Anna L
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Gomez, Maria F
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Gottlieb, Peter ...
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Greeley, Siri At ...
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Griffin, Kurt
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Hattersley, Andr ...
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Hirsch, Irl B
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Hivert, Marie-Fr ...
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Hood, Korey K
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Josefson, Jami L
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Kwak, Soo Heon
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Laffel, Lori M
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Lim, Siew S
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Loos, Ruth J F
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Ma, Ronald C W
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Mathieu, Chantal
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Mathioudakis, Ne ...
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Meigs, James B
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Misra, Shivani
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Mohan, Viswanath ...
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Murphy, Rinki
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Oram, Richard
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Owen, Katharine ...
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Ozanne, Susan E
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Pearson, Ewan R
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Perng, Wei
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Pollin, Toni I
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Pop-Busui, Rodic ...
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Pratley, Richard ...
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Redman, Leanne M
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Redondo, Maria J
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Reynolds, Rebecc ...
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Semple, Robert K
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Sherr, Jennifer ...
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Sims, Emily K
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Sweeting, Ariann ...
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Tuomi, Tiinamaij ...
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Udler, Miriam S
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Vesco, Kimberly ...
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Vilsbøll, Tina
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Wagner, Robert
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Rich, Stephen S
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Franks, Paul W
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
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