AMNE:(MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Dermatologi och venereologi)
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Validation of self-testing as a method to estimate the prevalence of nickel allergy
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- Josefson, Anna (author)
- Örebro universitet,Hälsoakademin
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- Svensson, Åke (author)
- Department of Dermatology, Skåne University Hospital, Lund University, Malmö, Sweden
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- Färm, Gunilla (author)
- Department of Dermatology, Karolinska University Hospital, Stockholm, Sweden
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- (creator_code:org_t)
- Society for Publication of Acta Dermato-Venereologica, 2011
- 2011
- English.
- In: Acta Dermato-Venereologica. - : Society for Publication of Acta Dermato-Venereologica. - 0001-5555 .- 1651-2057. ; 91:5, s. 526-530
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Background: Valid epidemiological tools are required for surveillance of the prevalence of contact allergy. Population based studies including patch testing is the most reliable method, but implies heavy expenses and logistical problems. Clinical data are not representative for the general population and questionnaires concerning contact allergy have a low validity. Self-testing might be a useful method but it has to be validated and evaluated.Objectives: To investigate the validity of self-patch testing for nickel allergy. Methods: Patients from three dermatology clinics were included consecutively when referred to patch testing. In total, 191 patients participated and they were provided with a self-test package including written instructions. The self-test was applied on the arm by the patient, on the same day as the patch test was applied on the back, in the clinic. The patient evaluated the self-test before the patch test reading at the clinic.Results: Patch test at dermatology clinic (‘gold standard’) gave 46/191 (24%) nickel-positive individuals. The sensitivity of the self-test was 72% (95% CI 57–84), the specificity was 91% (95% CI 85–95) and the proportion of agreement was 86% (95% CI 81–91).Conclusions: The validity of self-testing for nickel allergy was adequate in the studied population. To determine whether self-testing is a useful tool for measuring the prevalence of nickel allergy in the general population further studies will be needed.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Keyword
- contact allergy
- epidemiology
- patch test
- self-test
- sensitivity
- specificity
- MEDICINE
- MEDICIN
- Dermatology and venerology
- Dermatologi och venerologi
- Medicine
- Medicin
Publication and Content Type
- ref (subject category)
- art (subject category)
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- Josefson, Anna
- Svensson, Åke
- Färm, Gunilla
- Engfeldt, Malin
- Meding, Birgitta
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- MEDICAL AND HEALTH SCIENCES
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- Örebro University
- Karolinska Institutet
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