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Body mass index sta...
Body mass index standard deviation score and obesity in children with type 1 diabetes in the Nordic countries. HbA(1c) and other predictors of increasing BMISDS
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- Birkebaek, N. H. (author)
- Aarhus Univ, Denmark
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- Kahlert, J. (author)
- Aarhus Univ Hosp, Denmark
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- Bjarnason, R. (author)
- Landspitali Univ Hosp, Iceland; Univ Iceland, Iceland
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- Drivvoll, A. K. (author)
- Oslo Univ Hosp, Norway
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- Johansen, A. (author)
- Rigshosp, Denmark
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- Konradsdottir, E. (author)
- Landspitali Univ Hosp, Iceland; Univ Iceland, Iceland
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- Pundziute-Lycka, A. (author)
- Queen Silvia Childrens Hosp, Sweden
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- Samuelsson, Ulf (author)
- Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, H.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus
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- Skrivarhaug, T. (author)
- Oslo Univ Hosp, Norway
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- Svensson, J. (author)
- Univ Copenhagen, Denmark
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(creator_code:org_t)
- 2018-05-31
- 2018
- English.
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In: Pediatric Diabetes. - : WILEY. - 1399-543X .- 1399-5448. ; 19:7, s. 1198-1205
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Background: Intensified insulin therapy may increase body weight and cause obesity. This study compared body mass index standard deviation score (BMISDS) and obesity rate in children with type 1 diabetes (T1D) in Denmark, Iceland, Norway and Sweden, and uncovered predictors for increasing BMISDS. Methods: Data registered in the Nordic national childhood diabetes databases during the period 2008-2012 on children below 15 years with T1D for more than 3 months were compiled, including information on gender, age, diabetes duration, hemoglobin A(1c) (HbA(1c)), insulin dose, severe hypoglycemia (SH), treatment modality, height and weight. The Swedish reference chart for BMI was used for calculating BMISDS. Results: Totally, 11025 children (48% females) (30994 registrations) were included. Medians by the last recorded examination were: age, 13.5 years; diabetes duration, 4.3 years; HbA(1c), 7.9% (63 mmol/mol); insulin dose, 0.8 IU/kg/d and BMISDS, 0.70. Obesity rate was 18.5%. Adjusted mean BMISDS (BMISDS adj) was inversely related to HbA(1c) and directly to diabetes duration. Higher BMISDS adj was found in those with an insulin dose above 0.6 IU/kg/d, and in girls above 10 years. Pump users had higher BMISDS adj than pen users, and patients with registered SH had higher BMISDS adj than patients without SH (both P amp;lt; .001). Conclusion: Obesity rate in children with T1D in the Nordic countries is high, however, with country differences. Low HbA(1c), long diabetes duration, higher insulin dose, pump treatment and experiencing a SH predicted higher BMISDS. Diabetes caregivers should balance the risk of obesity and the benefit of a very low HbA(1c).
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- BMISDS; HbA(1c); insulin therapy modality; Nordic countries; obesity risk factors
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Birkebaek, N. H.
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Kahlert, J.
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Bjarnason, R.
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Drivvoll, A. K.
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Johansen, A.
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Konradsdottir, E ...
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show more...
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Pundziute-Lycka, ...
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Samuelsson, Ulf
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Skrivarhaug, T.
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Svensson, J.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
- Articles in the publication
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Pediatric Diabet ...
- By the university
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Linköping University