SwePub
Sök i LIBRIS databas

  Utökad sökning

L773:1876 2891
 

Sökning: L773:1876 2891 > Correlations betwee...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004974naa a2200457 4500
001oai:DiVA.org:oru-88420
003SwePub
008210112s2021 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-884202 URI
0247 a https://doi.org/10.3920/BM2020.00102 DOI
040 a (SwePub)oru
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Holster, S.u Faculty of Medicine and Health, School of Medical Sciences, Örebro University, Örebro, Sweden,Nutrition-Gut-Brain Interactions Research Centre4 aut
2451 0a Correlations between microbiota and metabolites after faecal microbiota transfer in irritable bowel syndrome
264 1b Wageningen Academic Publishers,c 2021
338 a print2 rdacarrier
500 a Funding Agencies:European Society of Clinical Nutrition and Metabolism (ESPEN)  Netherlands Organization for Scientific Research (NWO) 
520 a Faecal microbiota transfer (FMT) consists of the infusion of donor faecal material into the intestine of a patient with the aim to restore a disturbed gut microbiota. In this study, it was investigated whether FMT has an effect on faecal microbial composition, its functional capacity, faecal metabolite profiles and their interactions in 16 irritable bowel syndrome (IBS) patients. Faecal samples from eight different time points before and until six months after allogenic FMT (faecal material from a healthy donor) as well as autologous FMT (own faecal material) were analysed by 16S RNA gene amplicon sequencing and gas chromatography coupled to mass spectrometry (GS-MS). The results showed that the allogenic FMT resulted in alterations in the microbial composition that were detectable up to six months, whereas after autologous FMT this was not the case. Similar results were found for the functional profiles, which were predicted from the phylogenetic sequencing data. While both allogenic FMT as well as autologous FMT did not have an effect on the faecal metabolites measured in this study, correlations between the microbial composition and the metabolites showed that the microbe-metabolite interactions seemed to be disrupted after allogenic FMT compared to autologous FMT. This shows that FMT can lead to altered interactions between the gut microbiota and its metabolites in IBS patients. Further research should investigate if and how this affects efficacy of FMT treatments.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
653 a Colonic microbiota
653 a faecal microbiota transplantation
653 a metabolite profiles
653 a microbe-metabolite interactions
7001 a Repsilber, Dirk,d 1971-u Örebro universitet,Institutionen för medicinska vetenskaper,Nutrition-Gut-Brain Interactions Research Centre4 aut0 (Swepub:oru)drr
7001 a Geng, D.u Faculty of Business, Science and Engineering, School of Science and Technology, Örebro University, Örebro, Sweden,Man-Technology-Environmental Research Centre4 aut
7001 a Hyötyläinen, Tuulia,d 1971-u Örebro universitet,Institutionen för naturvetenskap och teknik,Man-Technology-Environmental Research Centre4 aut0 (Swepub:oru)tihn
7001 a Salonen, A.u Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland4 aut
7001 a Lindqvist, Carl Mårten,d 1979-u Örebro universitet,Institutionen för medicinska vetenskaper,Nutrition-Gut-Brain Interactions Research Centre4 aut0 (Swepub:oru)melt
7001 a Rajan, Sukithar K,d 1978-u Örebro universitet,Institutionen för medicinska vetenskaper,Nutrition-Gut-Brain Interactions Research Centr4 aut0 (Swepub:oru)srrn
7001 a de Vos, W. M.u Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Laboratory of Microbiology, Wageningen University and Research Centre, Wageningen, the Netherlands4 aut
7001 a Brummer, Robert Jan,d 1957-u Örebro universitet,Institutionen för medicinska vetenskaper,Nutrition-Gut-Brain Interactions Research Centre4 aut0 (Swepub:oru)rnbr
7001 a König, Julia,d 1983-u Örebro universitet,Institutionen för medicinska vetenskaper,Nutrition-Gut-Brain Interactions Research Centre4 aut0 (Swepub:oru)jkg
7102 a Faculty of Medicine and Health, School of Medical Sciences, Örebro University, Örebro, Swedenb Nutrition-Gut-Brain Interactions Research Centre4 org
7730 t Beneficial Microbesd : Wageningen Academic Publishersg 12:1, s. 17-30q 12:1<17-30x 1876-2883x 1876-2891
8564 u https://doi.org/10.3920/BM2020.0010y Fulltext
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-88420
8564 8u https://doi.org/10.3920/BM2020.0010

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy