WFRF:(Andersen Oluf 1941)
Sökning: WFRF:(Andersen Oluf 1941) > Multiple sclerosis ...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04954naa a2200637 4500 | |
| 001 | oai:gup.ub.gu.se/98437 | |
| 003 | SwePub | |
| 008 | 240528s2009 | |||||||||||000 ||eng| | |
| 009 | oai:research.chalmers.se:275b1d16-cca8-4978-b5d9-ce99257d3858 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/984372 URI |
| 024 | 7 | a https://doi.org/10.1111/j.1600-0404.2008.01131.x2 DOI |
| 024 | 7 | a https://research.chalmers.se/publication/984372 URI |
| 040 | a (SwePub)gud (SwePub)cth | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Ahlgren, Cecilia,d 1946u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation,University of Gothenburg4 aut0 (Swepub:gu)xahlce |
| 245 | 1 0 | a Multiple sclerosis incidence in the era of measles-mumps-rubella mass vaccinations. |
| 264 | 1 | b Hindawi Limited,c 2009 |
| 520 | a BACKGROUND: Viral childhood infections may be involved in the multiple sclerosis (MS) pathogenesis. Following national Swedish vaccination programs, measles sharply declined in the 1970s, and measles, mumps, and rubella were virtually eliminated in cohorts born from 1981. OBJECTIVES: To examine whether the vaccination induced reduction in these infections influences the MS incidence. In addition, the public health aspect justified an early evaluation of beneficial as well as harmful effects of mass vaccinations. MATERIALS AND METHODS: From an incidence material of 534 MS patients, born 1959-1990, we selected one unvaccinated cohort and four cohorts, each corresponding to a vaccination program (MS patients = 251). RESULTS: With the ability to detect a decrease by 30-35%, and an increase by 37-48% in the MS incidence in the first three cohorts, we found no vaccination related MS incidence changes. The background MS incidence showed a significant gradual age dependent increase. CONCLUSIONS: While the present follow-up provided limited power in the last cohort, there is no evidence as yet that the radical decline in three viral infections influenced the MS incidence. However, the increasing background MS incidence of unknown cause may have concealed a reduction in MS risk associated with mass vaccinations. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Fysiologi0 (SwePub)301062 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Physiology0 (SwePub)301062 hsv//eng |
| 653 | a Age Distribution | |
| 653 | a Cohort Studies | |
| 653 | a Comorbidity | |
| 653 | a Incidence | |
| 653 | a Measles | |
| 653 | a epidemiology | |
| 653 | a prevention & control | |
| 653 | a Measles-Mumps-Rubella Vaccine | |
| 653 | a adverse effects | |
| 653 | a therapeutic use | |
| 653 | a Multiple Sclerosis | |
| 653 | a epidemiology | |
| 653 | a Mumps | |
| 653 | a epidemiology | |
| 653 | a prevention & control | |
| 653 | a Proportional Hazards Models | |
| 653 | a Risk Reduction Behavior | |
| 653 | a Rubella | |
| 653 | a epidemiology | |
| 653 | a prevention & control | |
| 653 | a Sex Distribution | |
| 653 | a Sweden | |
| 653 | a epidemiology | |
| 653 | a epidemiology | |
| 700 | 1 | a Odén, Anders,d 1942u Gothenburg University,Göteborgs universitet,Institutionen för matematiska vetenskaper, matematisk statistik,Department of Mathematical Sciences, Mathematical Statistics,University of Gothenburg,Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)odena |
| 700 | 1 | a Torén, Kjell,d 1952u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institutionen för medicin, avdelningen för invärtesmedicin,Institute of Medicine, School of Public Health and Community Medicine,Institute of Medicine, Department of Internal Medicine,University of Gothenburg4 aut0 (Swepub:gu)xtorkj |
| 700 | 1 | a Andersen, Oluf,d 1941u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation,University of Gothenburg4 aut0 (Swepub:gu)xandeo |
| 710 | 2 | a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering4 org |
| 773 | 0 | t Acta neurologica Scandinavicad : Hindawi Limitedg 119:5, s. 313-20q 119:5<313-20x 1600-0404x 0001-6314 |
| 856 | 4 | u http://dx.doi.org/10.1111/j.1600-0404.2008.01131.xy FULLTEXT |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/98437 |
| 856 | 4 8 | u https://doi.org/10.1111/j.1600-0404.2008.01131.x |
| 856 | 4 8 | u https://research.chalmers.se/publication/98437 |
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