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A scientific journey from discovery to validation of efficacy in cancer patients : HAMLET and alpha1-oleate

Ho, James C.S. (author)
Lund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine,Nanyang Technological University
Ambite, Ines (author)
Lund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine
Mok, K. H. (author)
Trinity College Dublin
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Babjuk, Marek (author)
University Hospital Motol
Svanborg, Catharina (author)
Lund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,Cancerinfektion,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine,Cancer Infection,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments
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 (creator_code:org_t)
2021-09-30
2021
English.
In: Molecular and Cellular Oncology. - : Informa UK Limited. - 2372-3556. ; 8:5
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The protein-lipid complex alpha1-oleate, derived from HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells), is identified as a molecular entity with significant therapeutic potential. Structural characterization of the complex and results of a successful placebo-controlled clinical trial are presented.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Microbiology in the medical area (hsv//eng)

Keyword

bladder cancer
low toxicity
Novel cancer therapy
peptide-oleate complex
protein folding

Publication and Content Type

art (subject category)
ref (subject category)

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Ho, James C.S.
Ambite, Ines
Mok, K. H.
Babjuk, Marek
Svanborg, Cathar ...
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Basic Medicine
and Microbiology in ...
Articles in the publication
Molecular and Ce ...
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Lund University

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