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Sökning: WFRF:(Behr Joachim) > Reversal learning s...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003926naa a2200457 4500
001oai:DiVA.org:liu-134607
003SwePub
008170221s2017 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1346072 URI
024a https://doi.org/10.1111/ejn.134012 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Böhme, Rebeccau Linköpings universitet,Centrum för social och affektiv neurovetenskap,Medicinska fakulteten,Charite, Germany4 aut0 (Swepub:liu)rebbo11
2451 0a Reversal learning strategy in adolescence is associated with prefrontal cortex activation
264 c 2016-10-05
264 1b WILEY-BLACKWELL,c 2017
338 a print2 rdacarrier
500 a Funding Agencies|Volkswagen Foundation [II/84 452]; Bundesministerium fur Bildung und Forschung (BMBF) [01ZX1311E]; Deutsche Forschungsgemeinschaft [GRK-1123, HE 2597/13-1]
520 a Adolescence is a critical maturation period for human cognitive control and executive function. In this study, a large sample of adolescents (n=85) performed a reversal learning task during functional magnetic resonance imaging. We analyzed behavioral data using a reinforcement learning model to provide individually fitted parameters and imaging data with regard to reward prediction errors (PE). Following a model-based approach, we formed two groups depending on whether individuals tended to update expectations predominantly for the chosen stimulus or also for the unchosen one. These groups significantly differed in their problem behavior score obtained using the child behavior checklist (CBCL) and in a measure of their developmental stage. Imaging results showed that dorsolateral striatal areas covaried with PE. Participants who relied less on learning based on task structure showed less prefrontal activation compared with participants who relied more on task structure. An exploratory analysis revealed that PE-related activity was associated with pubertal development in prefrontal areas, insula and anterior cingulate. These findings support the hypothesis that the prefrontal cortex is implicated in mediating flexible goal-directed behavioral control.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng
653 a adolescents; prediction error; prefrontal cortex; reversal learning
700a Lorenz, Robert C.u Charite, Germany; Max Planck Institute Human Dev, Germany4 aut
700a Gleich, Tobiasu Charite, Germany; NeuroCure Excellence Cluster, Germany4 aut
700a Romund, Lydiau Charite, Germany4 aut
700a Pelz, Patriciau Charite, Germany4 aut
700a Golde, Sabrinau Charite, Germany4 aut
700a Flemming, Evau Charite, Germany4 aut
700a Wold, Andrewu Linköpings universitet,Centrum för social och affektiv neurovetenskap,Medicinska fakulteten4 aut0 (Swepub:liu)andwo24
700a Deserno, Lorenzu Charite, Germany; Max Planck Institute Human Cognit and Brain Science, Germany; Otto von Guericke University, Germany4 aut
700a Behr, Joachimu Charite, Germany; Charite, Germany; Medical School Brandenburg, Germany4 aut
700a Raufelder, Dianau Freie University, Germany4 aut
700a Heinz, Andreasu Charite, Germany4 aut
700a Beck, Anneu Charite, Germany4 aut
710a Linköpings universitetb Centrum för social och affektiv neurovetenskap4 org
773t European Journal of Neuroscienced : WILEY-BLACKWELLg 45:1, s. 129-137q 45:1<129-137x 0953-816Xx 1460-9568
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-134607
8564 8u https://doi.org/10.1111/ejn.13401

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