SwePub
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:DiVA.org:liu-54157"
 

Sökning: onr:"swepub:oai:DiVA.org:liu-54157" > Maternal Age at Bir...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004793naa a2200625 4500
001oai:DiVA.org:liu-54157
003SwePub
008100226s2010 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-541572 URI
0247 a https://doi.org/10.2337/db09-11662 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Cardwell, Chris Ru Queens University Belfast4 aut
2451 0a Maternal Age at Birth and Childhood Type 1 Diabetes: A Pooled Analysis of 30 Observational Studies
264 c 2009-10-29
264 1b American Diabetes Association,c 2010
338 a print2 rdacarrier
520 a OBJECTIVE-The aim if the study was to investigate whether children born to older mothers have an increased risk of type 1 diabetes by performing a pooled analysis of previous studies using individual patient data to adjust for recognized confounders. RESEARCH DESIGN AND METHODS-Relevant studies published before June 2009 were identified from MEDLINE, Web of Science, and EMBASE. Authors of studies were contacted and asked to provide individual patient data or conduct prespecified analyses. Risk estimates of type 1 diabetes by maternal age were calculated for each study, before and after adjustment for potential confounders. Meta-analysis techniques were used to derive combined odds ratios and to investigate heterogeneity among studies. RESULTS-Data were available for 5 cohort and 25 case-control studies, including 14,724 cases of type 1 diabetes. Overall, there was, on average, a 5% (95% CI 2-9) increase in childhood type 1 diabetes odds per 5-year increase in maternal age (P = 0.006), but there was heterogeneity among studies (heterogeneity I-2 = 70%). In studies with a low risk of bias, there was a more marked increase in diabetes odds of 10% per 5-year increase in maternal age. Adjustments for potential confounders little altered these estimates. CONCLUSIONS-There was evidence of a weak but significant linear increase in the risk of childhood type 1 diabetes across the range of maternal ages, but the magnitude of association varied between studies. A very small percentage of the increase in the incidence of childhood type 1 diabetes in recent years could be explained by increases in maternal age.
653 a MEDICINE
653 a MEDICIN
7001 a Stene, Lars Cu Norwegian Institute for Public Health4 aut
7001 a Joner, Geiru University of Oslo4 aut
7001 a Bulsara, Max Ku University of Notre Dame4 aut
7001 a Cinek, Ondreju Charles University Prague4 aut
7001 a Rosenbauer, Joachimu University of Dusseldorf4 aut
7001 a Ludvigsson, Johnnyu Östergötlands Läns Landsting,Linköpings universitet,Pediatrik,Hälsouniversitetet,Barn- och ungdomskliniken i Linköping4 aut0 (Swepub:liu)johlu29
7001 a Jane, Mireiau Department of Health, Public Health Div, Barcelona, Spain4 aut
7001 a Svensson, Jannetu Glostrup University Hospital4 aut
7001 a Goldacre, Michael Ju University Oxford4 aut
7001 a Waldhoer, Thomasu Medical University of Vienna4 aut
7001 a Jarosz-Chobot, Przemyslawau Medical University of Silesia4 aut
7001 a Gimeno, Suely G Au University Fed Sao Paulo4 aut
7001 a Chuang, Lee-Mingu National Taiwan University Hospital4 aut
7001 a Parslow, Roger Cu University of Leeds4 aut
7001 a Wadsworth, Emma J Ku Cardiff University4 aut
7001 a Chetwynd, Amandau University of Lancaster4 aut
7001 a Pozzilli, Paolou University Campus Biomed, Rome, Italy4 aut
7001 a Brigis, Girtsu Riga Stradins University4 aut
7001 a Urbonaite, Broneu Kaunas University of Medicine4 aut
7001 a Sipetic, Sandrau University of Belgrade4 aut
7001 a Schober, Edithu Medical University of Vienna4 aut
7001 a Devoti, Gabrieleu University of Lecce4 aut
7001 a Ionescu-Tirgoviste, Constantinu N Paulescu Institute Diabet4 aut
7001 a de Beaufort, Carine Eu Pediat Clin, Luxembourg4 aut
7001 a Stoyanov, Denkau Childrens Diabet Centre, Sofia, Bulgaria4 aut
7001 a Buschard, Karstenu Rigshosp, Bartholin Institute, DK-2100 Copenhagen, Denmark4 aut
7001 a Patterson, Chris Cu Queens University Belfast4 aut
7102 a Queens University Belfastb Norwegian Institute for Public Health4 org
7730 t DIABETESd : American Diabetes Associationg 59:2, s. 486-494q 59:2<486-494x 0012-1797x 1939-327X
8564 u http://diabetes.diabetesjournals.org/content/59/2/486.full.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-54157
8564 8u https://doi.org/10.2337/db09-1166

Hitta via bibliotek

  • DIABETES (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy