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GWAS Meta-Analysis ...
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.
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- Docherty, Anna R (author)
- Huntsman Mental Health Institute, Salt Lake City, United States; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States; Department of Psychiatry, Virginia Commonwealth University, Richmond, United States
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- Mullins, Niamh (author)
- Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States
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- Ashley-Koch, Allison E (author)
- Duke Molecular Physiology Institute, Duke-University Medical Center, NC, Durham, United States
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- Qin, Xuejun (author)
- Duke Molecular Physiology Institute, Duke-University Medical Center, NC, Durham, United States
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- Coleman, Jonathan R I (author)
- Nihr Maudsley Biomedical Research Centre at South London, Maudsley Nhs Foundation Trust, King's College London, United Kingdom; Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom
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- Shabalin, Andrey (author)
- Huntsman Mental Health Institute, Salt Lake City, United States; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States
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- Kang, JooEun (author)
- Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt Genetics Institute, TN, Nashville, United States
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- Murnyak, Balasz (author)
- Huntsman Mental Health Institute, Salt Lake City, United States; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States
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- Wendt, Frank (author)
- Department of Psychiatry, Department of Psychiatry, Yale University School of Medicine, CT, New Haven, United States
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- Adams, Mark (author)
- Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom
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- Campos, Adrian I (author)
- Mental Health and Neuroscience Research Program
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- DiBlasi, Emily (author)
- Huntsman Mental Health Institute, Salt Lake City, United States; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States
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- Fullerton, Janice M (author)
- Mental Health and Neuroscience Research Program
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- Kranzler, Henry R (author)
- Mental Health and Neuroscience Research Program
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- Bakian, Amanda V (author)
- Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States
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- Monson, Eric T (author)
- Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States
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- Rentería, Miguel E (author)
- Department of Population Health, Qimr Berghofer Medical Research Institute, Brisbane, Australia
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- Walss-Bass, Consuelo (author)
- Institute for Molecular Bioscience
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- Andreassen, Ole A (author)
- School of Biomedical Sciences, Faculty of Medicine
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- Behera, Chittaranjan (author)
- Child Health Research Centre
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- Bulik, Cynthia M (author)
- Karolinska Institutet
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- Edenberg, Howard J (author)
- Neuroscience Research Australia, Sydney, Australia
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- Kessler, Ronald C (author)
- School of Medical Sciences
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- Mann, J John (author)
- School of Psychology, Mexico
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- Nurnberger, John I (author)
- School of Psychiatry, University of New South Wales, Sydney, Australia
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- Pistis, Giorgio (author)
- Department of Psychiatry, Center for Neurobiology and Behavior
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- Streit, Fabian (author)
- Department of Psychiatry
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- Ursano, Robert J (author)
- Center for Applied Genomics, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States
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- Polimanti, Renato (author)
- Department of Psychiatry, Department of Psychiatry, Yale University School of Medicine, CT, New Haven, United States
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- Dennis, Michelle (author)
- Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, NC, Durham, United States,Department of Pathology, University of Utah School of Medicine, Salt Lake City, United States
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- Garrett, Melanie (author)
- Duke Molecular Physiology Institute, Duke University Medical Center, NC, Durham, United States
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- Hair, Lauren (author)
- Crescenz Vamc, Visn 4 Mirecc, Philadelphia, United States
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- Harvey, Philip (author)
- Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, United States
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- Hauser, Elizabeth R (author)
- Division of Mental Health and Addiction
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- Hauser, Michael A (author)
- Duke Molecular Physiology Institute, Duke-University Medical Center, NC, Durham, United States
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- Huffman, Jennifer (author)
- Department of Medical Genetics, Oslo University Hospital, Oslo, Norway,Comprehensive Center for Clinical Neurosciences and Mental Health
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- Jacobson, Daniel (author)
- Norment, University of Oslo, Oslo, Norway,Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom
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- Madduri, Ravi (author)
- Department of Forensic Medicine, All-India Institute for Medical Sciences, Delhi, India
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- McMahon, Benjamin (author)
- Department of Medical Epidemiology and Biostatistics, National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Sweden
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- Oslin, David W (author)
- Karolinska Institutet
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- Trafton, Jodie (author)
- Centre for Psychiatry Research
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- Awasthi, Swapnil (author)
- Department of Clinical Neuroscience
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- Berrettini, Wade H (author)
- Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden,Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Department of Genetic Epidemiology in Psychiatry, Mannheim, Germany
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- Bohus, Martin (author)
- Department of Nutrition
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- Chang, Xiao (author)
- [NO CONNECTION TO ANY AFFILIATION IN XML],Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan
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- Chen, Hsi-Chung (author)
- Department of Genetics, University of North Carolina at Chapel Hill, United States
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- Chen, Wei J (author)
- Department of Medical and Molecular Genetics
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- Christensen, Erik D (author)
- Human Genetics Branch, Intramural Research Program, Nimh, Bethesda, United States
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- Crow, Scott (author)
- Department of Biochemistry and Molecular Biology
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- Duriez, Philibert (author)
- Department of Psychiatry, Indiana University School of Medicine, Indianapolis, United States
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- Edwards, Alexis C (author)
- Department of Psychiatry, Virginia Commonwealth University, Richmond, United States
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- Fernández-Aranda, Fernando (author)
- Department of Health Care Policy, Harvard Medical School, Boston, United States
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- Galfalvy, Hanga (author)
- Departments of Psychiatry and Radiology
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- Gandal, Michael (author)
- Department of Biostatistics
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- Gorwood, Philip (author)
- Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, United States
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- Guo, Yiran (author)
- Department of Psychiatry, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland
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- Hafferty, Jonathan D (author)
- Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom
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- Hakonarson, Hakon (author)
- Theoretical Division, Los Alamos National Laboratory, NM, Los Alamos, United States,Molecular Brain Science, Centre for Addiction and Mental Health,Stanley Center for Psychiatric Research,National Institute of Mental Health, Klecany, Czech Republic,Department of Psychiatry and Behavioral Sciences, State University of New York Downstate Medical Center, New York, United States
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- Halmi, Katherine A (author)
- Department of Psychiatry, Uniformed University of the Health Sciences, Bethesda, United States
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- Hishimoto, Akitoyo (author)
- Durham Veterans Affairs Health Care System, NC, Durham, United States
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- Jain, Sonia (author)
- Miami Va Health Care System, Miami, United States,School of Psychology and Counseling, Queensland University of Technology, Brisbane, Australia
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- Jamain, Stéphane (author)
- Cooperative Studies Program Epidemiology Center, Durham Veterans Affairs Health Care System, NC, Durham, United States,Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy; Department of Psychiatry and Behavioral Sciences, Suny Upstate Medical University, NY, Syracuse, United States
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- Jiménez-Murcia, Susana (author)
- Boston Va Health Care System, Boston, United States
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- Johnson, Craig (author)
- Oak Ridge National Laboratory, TN, Oak Ridge, United States
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- Kaplan, Allan S (author)
- Argonne National Laboratory, University of Chicago Consortium for Advanced Science and Engineering, Chicago, United States
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Kaye, Walter H (author)
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- Keel, Pamela K (author)
- Corporal Michael J. Crescenz Va Medical Center, Visn 4 Mental Illness Research Education, and Clinical Center, Philadelphia, United States
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- Kennedy, James L (author)
- Va Program Evaluation and Resource Center, Va Palo Alto Health Care System, CA, Palo Alto, United States,Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
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- Kim, Minsoo (author)
- Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Berlin, Germany
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- Klump, Kelly L (author)
- Central Institute of Mental Health, Medical Faculty Mannheim, Department of Psychosomatic Medicine and Psychotherapy, University of Heidelberg, Mannheim, Germany
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- Levey, Daniel F (author)
- Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, CT, New Haven, United States
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- Li, Dong (author)
- Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, United States
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Liao, Shih-Cheng (author)
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- Lieb, Klaus (author)
- Center for Neuropsychiatric Research, National Health Research Institutes, Miaoli County, Taiwan
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- Lilenfeld, Lisa (author)
- Karolinska Institutet
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- Marshall, Christian R (author)
- Utah Office of the Medical Examiner, Utah Department of Health and Human Services, Taylorsville, United States
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- Mitchell, James E (author)
- Department of Psychiatry, University of Minnesota, Minneapolis, United States
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- Okazaki, Satoshi (author)
- Ghu Paris Psychiatrie et Neurosciences, Hôpital Sainte-Anne, Paris, France
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- Otsuka, Ikuo (author)
- Institute of Psychiatry and Neuroscience of Paris, Université Paris Cité, Inserm U1266, Paris, France
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- Pinto, Dalila (author)
- Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States
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- Powers, Abigail (author)
- Department of Psychiatry, University Hospital Bellvitge-IDIBELL, Ciberobn, Barcelona, Spain,Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom
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- Ramoz, Nicolas (author)
- [NO CONNECTION TO ANY AFFILIATION IN XML]
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- Ripke, Stephan (author)
- Institute of Medical Science, Japan,McLaughlin Center, United States
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Roepke, Stefan (author)
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- Rozanov, Vsevolod (author)
- Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada
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- Scherer, Stephen W (author)
- Department of Psychiatry and Biobehavioral Science, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, United States
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- Schmahl, Christian (author)
- Department of Psychiatry, Weill Cornell Medical College, New York, United States
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- Sokolowski, Marcus (author)
- Karolinska Institutet
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- Starnawska, Anna (author)
- Biostatistics Research Center, Herbert Wertheim School of Public Health and Human Longevity Science, United States
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- Strober, Michael (author)
- [NO CONNECTION TO ANY AFFILIATION IN XML]
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- Su, Mei-Hsin (author)
- Institute for Genomic Medicine, Center for Behavioral Genomics
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- Thornton, Laura M (author)
- School of Public Health, University of California San Diego, La Jolla, United States
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- Treasure, Janet (author)
- Translational Neuropsychiatry, Fondation FondaMental, University of Paris-Est-Créteil, Inserm, Imrb, Créteil, France,Department of Psychiatry and Amsterdam Neuroscience, Amsterdam Umc, Vrije Universiteit, Amsterdam, Netherlands
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- Ware, Erin B (author)
- Eating Recovery Center, Denver, United States
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- Watson, Hunna J (author)
- Centre for Addiction and Mental Health, Toronto, Canada
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Witt, Stephanie H (author)
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- Woodside, D Blake (author)
- Molecular Brain Science, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada
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- Yilmaz, Zeynep (author)
- Department of Psychiatry, University of California San Diego, San Diego, United States
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- Zillich, Lea (author)
- Department of Psychology, Florida State University, Tallahassee, United States
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- Adolfsson, Rolf (author)
- Umeå universitet,Psykiatri,Department of Psychology, Michigan State University, Lansing, United States
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- Agartz, Ingrid (author)
- Karolinska Institutet
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- Alda, Martin (author)
- Department of Psychiatry and Psychotherapy, University Medical Center, Mainz, Germany
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- Alfredsson, Lars (author)
- Department of Clinical Psychology, Chicago School of Professional Psychology, DC, Washington, United States
-
- Appadurai, Vivek (author)
- Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, United States
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- Artigas, María Soler (author)
- Department of Paediatric Laboratory Medicine
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- Van der Auwera, Sandra (author)
- Department of Genetics and Genomic Biology, Hospital for Sick Children, Toronto, Canada
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- Azevedo, M Helena (author)
- Department of Psychiatry and Behavioral Science, University of North Dakota School of Medicine and Health Sciences, Fargo, United States
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- Bass, Nicholas (author)
- Department of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan
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Bau, Claiton H D (author)
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- Baune, Bernhard T (author)
- Program in Medical and Population Genetics, Broad Institute, MA, Cambridge, United States,Department of Psychiatry, Virginia Commonwealth University, Richmond, United States
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- Bellivier, Frank (author)
- Analytical and Translational Genetics Unit
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- Berger, Klaus (author)
- [NO CONNECTION TO ANY AFFILIATION IN XML]
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- Biernacka, Joanna M (author)
- Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, United States
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Bigdeli, Tim B (author)
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- Binder, Elisabeth B (author)
- Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, HumboldtUniversität zu Berlin, Department of Psychiatry, Berlin Institute of Health, Campus Benjamin Franklin, Berlin, Germany
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- Boehnke, Michael (author)
- Department of Psychology, Saint Petersburg State University, Saint Petersburg, Russian Federation
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- Boks, Marco P (author)
- Department of Borderline Disorders and Psychotherapy, V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology, Saint Petersburg, Russian Federation
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Braff, David L (author)
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- Bryant, Richard (author)
- Centre for Integrative Sequencing, ISEQ Aaruhus, Denmark
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- Budde, Monika (author)
- Department of Biomedicine, IPSYCH, Denmark
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- Byrne, Enda M (author)
- Lundbeck Foundation Initiative for Integrative Psychiatric Research, Denmark
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- Cahn, Wiepke (author)
- National Centre for Register-Based Research
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- Castelao, Enrique (author)
- Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark
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- Cervilla, Jorge A (author)
- Psychosis Research Unit, Aarhus University Hospital, Risskov, Aarhus, Denmark
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- Chaumette, Boris (author)
- Institute of Psychiatry, Psychology, and Neuroscience, Department of Psychological Medicine, King's College London, United Kingdom
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- Corvin, Aiden (author)
- National Institute for Health Research Biomedical Research Centre, King's College London and South London, Maudsley National Health Service Foundation Trust, London, United Kingdom
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- Craddock, Nicholas (author)
- Population Studies Center and Survey Research Center, Institute for Social Research
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- Djurovic, Srdjan (author)
- Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, United States
-
- Foo, Jerome C (author)
- School of Psychology, Curtin University, Perth, Australia
-
- Forstner, Andreas J (author)
- Division of Paediatrics, University of Western Australia, Perth, Australia
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- Frye, Mark (author)
- Centre for Mental Health and Program for Eating Disorders, University Health Network, Toronto, Canada
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Gatt, Justine M (author)
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- Giegling, Ina (author)
- Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway
-
- Grabe, Hans J (author)
- Norment, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
-
- Green, Melissa J (author)
- Department of Psychiatry, Dalhousie University, Halifax, Canada
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Grevet, Eugenio H (author)
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- Grigoroiu-Serbanescu, Maria (author)
- Institute of Biological Psychiatry, Copenhagen Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark
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- Gutierrez, Blanca (author)
- IPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Copenhagen, Denmark
-
- Guzman-Parra, Jose (author)
- Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain
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- Hamshere, Marian L (author)
- Karolinska Institutet
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- Hartmann, Annette M (author)
- Department of Genetics, Microbiology, and Statistics, University of Barcelona, Barcelona, Spain
-
- Hauser, Joanna (author)
- Duke Molecular Physiology Institute, Duke-University Medical Center, NC, Durham, United States
-
- Heilmann-Heimbach, Stefanie (author)
- Psychiatric Genetics Unit, Groupof Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
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- Hoffmann, Per (author)
- Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany
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- Ising, Marcus (author)
- German Centre for Neurodegenerative Diseases (DZNE), Partner Site Rostock/Greifswald, Greifswald, Germany
-
- Jones, Ian (author)
- Department of Psychiatry, University of Coimbra, Coimbra, Portugal
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- Jones, Lisa A (author)
- Division of Psychiatry, University College London, United Kingdom
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- Jonsson, Lina, 1982 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry,Laboratory of Developmental Psychiatry, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
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- Kahn, René S (author)
- Department of Genetics, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil
-
- Kelsoe, John R (author)
- Department of Psychiatry, Melbourne Medical School, University of Melbourne, Melbourne, Australia
-
- Kendler, Kenneth S (author)
- [NO CONNECTION TO ANY AFFILIATION IN XML]
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- Kloiber, Stefan (author)
- Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany
-
- Koenen, Karestan C (author)
- Department of Psychiatry and Addiction Medicine, Assistance Publique-Hôpitaux de Paris, Paris, France
-
- Kogevinas, Manolis (author)
- Paris Bipolar and Trd Expert Centers, FondaMental Foundation, Paris, France
-
- Krebs, Marie-Odile (author)
- Team 1, Biomarkers of Relapse and Therapeutic Response in Addiction and Mood Disorders, Inserm, UMR-S 1144, Paris, France
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- Landén, Mikael (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Extern,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry,External,Psychiatry, Université Paris Cité, Paris, France
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Leboyer, Marion (author)
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Lee, Phil H (author)
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- Levinson, Douglas F (author)
- Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany
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- Liao, Calwing (author)
- Psychiatry, Umc Utrecht Brain Center, Utrecht, Netherlands
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- Lissowska, Jolanta (author)
- Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain
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- Mayoral, Fermin (author)
- Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany
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McElroy, Susan L (author)
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- McGrath, Patrick (author)
- Mental Health Unit, Department of Psychiatry, Faculty of Medicine, Granada University Hospital Complex, University of Granada, Granada, Spain
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- McGuffin, Peter (author)
- Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom
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- McQuillin, Andrew (author)
- Institut de Psychiatrie, Cnrs Gdr 3557, Paris, France,Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom
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- Mehta, Divya (author)
- Department of Evaluation Prevention, and Therapeutic Innovation, Ghu Paris Psychiatrie et Neurosciences, Paris, France
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- Melle, Ingrid (author)
- Institute of Psychiatry and Neuroscience of Paris, Inserm U1266, Team Pathophysiology of Psychiatric Diseases, Université de Paris, Paris, France
-
- Mitchell, Philip B (author)
- Institute of Medical Genetics and Pathology, University Hospital Basel, Department of Biomedicine, University of Basel, Basel, Switzerland
-
- Molina, Esther (author)
- Institute of Human Genetics, University of Bonn, School of Medicine, University Hospital Bonn, Bonn, Germany
-
- Morken, Gunnar (author)
- Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland
-
- Nievergelt, Caroline (author)
- Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom
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- Nöthen, Markus M (author)
- Norment, Kg Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway
-
- O'Donovan, Michael C (author)
- Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany,Mental Health and Neuroscience Research Program
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- Ophoff, Roel A (author)
- Center for HumanGenetics,Universityof Marburg, Marburg, Germany
-
- Owen, Michael J (author)
- Department of Psychiatry and Psychology, Mayo Clinic, MN, Rochester, United States
-
- Pato, Carlos (author)
- Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, IL, Evanston, United States
-
- Pato, Michele T (author)
- Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, United States
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Penninx, Brenda W J H (author)
-
- Potash, James B (author)
- Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria
-
- Power, Robert A (author)
- Department of Psychological Medicine, University of Worcester, Worcester, United Kingdom
-
- Preisig, Martin (author)
- Adhd Outpatient Program, Adult Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
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- Quested, Digby (author)
- Department of Psychiatry, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil
-
- Ramos-Quiroga, Josep Antoni (author)
- Biometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania
-
- Reif, Andreas (author)
- Department of Psychiatry, Faculty of Medicine, Biomedical Research Centre (CIBM), University of Granada, Granada, Spain
-
- Ribasés, Marta (author)
- Biomedicine Institute (IBIMA), Mental Health Department, University Regional Hospital, Málaga, Spain
-
- Richarte, Vanesa (author)
- Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
-
- Rietschel, Marcella (author)
- Max Planck Institute of Psychiatry, Munich, Germany
-
- Rivera, Margarita (author)
- Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom
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Roberts, Andrea (author)
-
- Roberts, Gloria (author)
- Department of Psychiatry and Neuroscience
-
- Rouleau, Guy A (author)
- Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
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Rovaris, Diego L (author)
-
- Sanders, Alan R (author)
- Department of Epidemiology
-
- Schofield, Peter R (author)
- Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, United States
-
- Schulze, Thomas G (author)
- Center for Research in Environmental Epidemiology (CREAL), Barcelona, Spain
-
- Scott, Laura J (author)
- Inserm, AP-HP, Imrb, Translational Neuropsychiatry, Dmu Impact, Fhu Adapt, Fondation FondaMental, Université Paris Est, Créteil, France
-
- Serretti, Alessandro (author)
- Inserm, Paris, France
-
- Shi, Jianxin (author)
- Faculté de Médecine, Université Paris Est, Créteil, France
-
- Sirignano, Lea (author)
- Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, United States
-
- Sklar, Pamela (author)
- Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, United States
-
- Smeland, Olav B (author)
- Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
-
- Smoller, Jordan W (author)
- Research Institute, Lindner Center of Hope, OH, Mason, United States
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Sonuga-Barke, Edmund J S (author)
-
- Trzaskowski, Maciej (author)
- Institute of Clinical Medicine, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway
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- Tsuang, Ming T (author)
- Department of Nursing, Faculty of Health Sciences and Biomedical Research Centre (CIBM), University of Granada, Granada, Spain; Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology-NTNU, Trondheim, Norway
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- Turecki, Gustavo (author)
- Psychiatry, St. Olavs University Hospital, Trondheim, Norway
-
- Vilar-Ribó, Laura (author)
- Psychiatry, Erasmus University Medical Center, Rotterdam, Netherlands
-
- Vincent, John B (author)
- Robert Wood Johnson Medical School, Rutgers New Jersey Medical School, University Behavioral Health Care, Rutgers University, NJ, Piscataway, United States
-
- Völzke, Henry (author)
- Robert Wood Johnson Medical School, Rutgers New Jersey Medical School, Rutgers University, NJ, Piscataway, United States
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Walters, James T R (author)
-
- Weickert, Cynthia Shannon (author)
- Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, United States
-
- Weickert, Thomas W (author)
- Genetics, BioMarin Pharmaceuticals, London, United Kingdom,Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark
-
- Weissman, Myrna M (author)
- St. Edmund Hall, University of Oxford, Oxford, United Kingdom
-
- Williams, Leanne M (author)
- Department of Psychiatry, University of Oxford, Oxford, United Kingdom
-
- Wray, Naomi R (author)
- Department of Psychiatry Psychosomatic Medicine, and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany
-
- Zai, Clement C (author)
- Department of Biochemistry and Molecular Biology Ii, Institute of Neurosciences, Biomedical Research Centre (CIBM), University of Granada, Granada, Spain
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- Agerbo, Esben (author)
- Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal Neurological Institute and Hospital, Montreal, Canada
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- Børglum, Anders D (author)
- Department of Physiology and Biophysics, Instituto de Ciencias Biomedicas Universidade de Sao Paulo, São Paulo, Brazil
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- Breen, Gerome (author)
- Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States; Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom
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Demontis, Ditte (author)
-
- Erlangsen, Annette (author)
- Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany; Centre for Mental Health Research, Australian National University, Canberra, Australia; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States; Danish Research Institute for Suicide Prevention, Mental Health Centre Copenhagen, Copenhagen, Denmark
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- Gelernter, Joel (author)
- Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, CT, New Haven, United States
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Glatt, Stephen J (author)
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- Hougaard, David M (author)
- Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, United States; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
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- Hwu, Hai-Gwo (author)
- Institute of Psychology, Psychiatry, and Neuroscience, King's College London, United Kingdom; Department of Psychiatry, National Taiwan University Hospital, College of Medicine, Taipei, Taiwan
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- Kuo, Po-Hsiu (author)
- Department of Psychiatry, McGill University, Montreal, Canada
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- Lewis, Cathryn M (author)
- Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom; Department of Medical and Molecular Genetics, King's College London, United Kingdom
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- Li, Qingqin S (author)
- Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; Neuroscience, Janssen Research and Development, NJ, Titusville, United States
-
- Liu, Chih-Min (author)
- Division of Translational Epidemiology, New York State Psychiatric Institute, New York, United States
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- Martin, Nicholas G (author)
- IPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
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McIntosh, Andrew M (author)
-
- Medland, Sarah E (author)
- Centre for Mental Health Research, Australian National University, Canberra, Australia
-
- Mors, Ole (author)
- Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States
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- Nordentoft, Merete (author)
- Mental Health Center Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark
-
Olsen, Catherine M (author)
-
- Porteous, David (author)
- Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom
-
Smith, Daniel J (author)
-
- Stahl, Eli A (author)
- Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States; Analytical Genetics and Data Science, Regeneron Genetics Center, NY, Tarrytown, United States
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- Stein, Murray B (author)
- Biostatistics Research Center, Herbert Wertheim School of Public Health and Human Longevity Science, United States; School of Public Health, University of California San Diego, La Jolla, United States
-
- Wasserman, Danuta (author)
- Lime, Department of Clinical Neuroscience
-
Werge, Thomas (author)
-
- Whiteman, David C (author)
- Department of Population Health, Qimr Berghofer Medical Research Institute, Brisbane, Australia
-
- Willour, Virginia (author)
- Department of Psychiatry, University of Iowa, Iowa City, United States
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- Coon, Hilary (author)
- Huntsman Mental Health Institute, Salt Lake City, United States; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States; Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, United States; Department of Psychiatry, University of Iowa, Iowa City, United States
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- Beckham, Jean C (author)
- Visn 6 Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham Veterans Affairs Health Care System, NC, Durham, United States; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, NC, Durham, United States
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- Kimbrel, Nathan A (author)
- Visn 6 Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham Veterans Affairs Health Care System, NC, Durham, United States; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, NC, Durham, United States
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- Ruderfer, Douglas M (author)
- Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt Genetics Institute, TN, Nashville, United States; Department of Biomedical Informatics, Vanderbilt University Medical Center, TN, Nashville, United States; Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, TN, Nashville, United States
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(creator_code:org_t)
- American Psychiatric Association Publishing, 2023
- 2023
- English.
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In: The American journal of psychiatry. - : American Psychiatric Association Publishing. - 1535-7228 .- 0002-953X. ; 180:10, s. 723-738
- Related links:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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http://kipublication...
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Abstract
Subject headings
Close
- Suicidal behavior is heritable and is a major cause of death worldwide. Two large-scale genome-wide association studies (GWASs) recently discovered and cross-validated genome-wide significant (GWS) loci for suicide attempt (SA). The present study leveraged the genetic cohorts from both studies to conduct the largest GWAS meta-analysis of SA to date. Multi-ancestry and admixture-specific meta-analyses were conducted within groups of significant African, East Asian, and European ancestry admixtures.This study comprised 22 cohorts, including 43,871 SA cases and 915,025 ancestry-matched controls. Analytical methods across multi-ancestry and individual ancestry admixtures included inverse variance-weighted fixed-effects meta-analyses, followed by gene, gene-set, tissue-set, and drug-target enrichment, as well as summary-data-based Mendelian randomization with brain expression quantitative trait loci data, phenome-wide genetic correlation, and genetic causal proportion analyses.Multi-ancestry and European ancestry admixture GWAS meta-analyses identified 12 risk loci at p values <5×10-8. These loci were mostly intergenic and implicated DRD2, SLC6A9, FURIN, NLGN1, SOX5, PDE4B, and CACNG2. The multi-ancestry SNP-based heritability estimate of SA was 5.7% on the liability scale (SE=0.003, p=5.7×10-80). Significant brain tissue gene expression and drug set enrichment were observed. There was shared genetic variation of SA with attention deficit hyperactivity disorder, smoking, and risk tolerance after conditioning SA on both major depressive disorder and posttraumatic stress disorder. Genetic causal proportion analyses implicated shared genetic risk for specific health factors.This multi-ancestry analysis of suicide attempt identified several loci contributing to risk and establishes significant shared genetic covariation with clinical phenotypes. These findings provide insight into genetic factors associated with suicide attempt across ancestry admixture populations, in veteran and civilian populations, and in attempt versus death.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Medicinsk genetik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medical Genetics (hsv//eng)
Keyword
- Humans
- Genome-Wide Association Study
- Suicide
- Attempted
- Depressive Disorder
- Major
- genetics
- Risk Factors
- Suicidal Ideation
- Polymorphism
- Single Nucleotide
- genetics
- Genetic Predisposition to Disease
- genetics
- Genetic Loci
- genetics
Publication and Content Type
- ref (subject category)
- art (subject category)
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University of Gothenburg
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Umeå University
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Karolinska Institutet