WFRF:(Hellquist Henrik)
Sökning: WFRF:(Hellquist Henrik) > Salivary duct carci...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03769naa a2200481 4500 | |
| 001 | oai:DiVA.org:oru-49533 | |
| 003 | SwePub | |
| 008 | 160325s1994 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-495332 URI |
| 024 | 7 | a https://doi.org/10.1002/path.17117201082 DOI |
| 040 | a (SwePub)oru | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Hellquist, Henrik B.u Department of Pathology, Örebro Medical Center Hospital, Örebro, Sweden4 aut |
| 245 | 1 0 | a Salivary duct carcinoma :b a highly aggressive salivary gland tumour with overexpression of c-erbB-2 |
| 264 | c 2005-06-15 | |
| 264 | 1 | a West Sussex, United Kingdom :b John Wiley & Sons,c 1994 |
| 338 | a print2 rdacarrier | |
| 520 | a The clinicopathological and immunocytochemical features of nine cases of salivary duct carcinoma are described. This relatively rare tumour, which only recently has been widely recognized as a separate entity, is highly malignant and caused the death in eight of the patients. The tumour cells are arranged in cribriform and solid growth patterns, where the solid tumour nests frequently have comedo necrosis, and a fibrous, often sclerotic, stroma is present. The infiltrating desmoplasmic component and the diffuse invasive growth into adjacent adipose parotid tissue have similarities to ductal breast carcinoma. Immunocytochemical investigation of salivary duct carcinoma showed constant overexpression of c-erbB-2 as detected by membrane accentuation, and high proliferative activity as detected by nuclear positivity for MIB 1 (Ki-67). Changes in the expression of p53 and retinoblastoma gene product do not constitute a constant event in salivary duct carcinoma. A few of the tumours showed scattered cells with distinct nuclear positivity for both progesterone and oestrogen receptors. We emphasize that this highly malignant salivary gland tumour has a characteristic morphology, may not be as rare as previously considered, and that prompt and aggressive therapy is needed. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Klinisk laboratoriemedicin0 (SwePub)302232 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Clinical Laboratory Medicine0 (SwePub)302232 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Oto-rhino-laryngologi0 (SwePub)302182 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Otorhinolaryngology0 (SwePub)302182 hsv//eng |
| 653 | a Adenocarcinoma | |
| 653 | a c-erbB-2 | |
| 653 | a oncogenes | |
| 653 | a p53 | |
| 653 | a Ki-67 | |
| 653 | a steroid receptors | |
| 653 | a salivary gland neoplasms | |
| 653 | a salivary duct carcinoma | |
| 653 | a Biomedicin | |
| 653 | a Biomedicine | |
| 700 | 1 | a Karlsson, Mats G.,d 1960-u Department of Pathology, Örebro Medical Center Hospital, Örebro, Sweden4 aut0 (Swepub:oru)mskn |
| 700 | 1 | a Nilsson, Christeru Department of Otorhinolaryngology, Örebro Medical Center Hospital, Örebro, Sweden4 aut |
| 710 | 2 | a Department of Pathology, Örebro Medical Center Hospital, Örebro, Swedenb Department of Otorhinolaryngology, Örebro Medical Center Hospital, Örebro, Sweden4 org |
| 773 | 0 | t Journal of Pathologyd West Sussex, United Kingdom : John Wiley & Sonsg 172:1, s. 35-44q 172:1<35-44x 0022-3417x 1096-9896 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-49533 |
| 856 | 4 8 | u https://doi.org/10.1002/path.1711720108 |
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