Sökning: WFRF:(Holmqvist Peter)
> (2000-2004) >
Molecular identific...
Molecular identification and developmental expression of UV and green opsin mRNAs in the pineal organ of the Atlantic halibut.
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- Forsell, Johan (författare)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Holmqvist, Bo (författare)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Funktionell zoologi,Biologiska institutionen,Naturvetenskapliga fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Functional zoology,Department of Biology,Faculty of Science
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- Ekström, Peter (författare)
- Lund University,Lunds universitet,Funktionell zoologi,Biologiska institutionen,Naturvetenskapliga fakulteten,Functional zoology,Department of Biology,Faculty of Science
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(creator_code:org_t)
- 2002
- 2002
- Engelska.
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Ingår i: Developmental Brain Research. - 0165-3806. ; 136:1, s. 51-62
- Relaterad länk:
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http://www.ncbi.nlm....
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visa fler...
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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visa färre...
Abstract
Ämnesord
Stäng
- The pineal organ is the only differentiated photoreceptor organ present in embryos and early larvae of the Atlantic halibut (Hippoglossus hippoglossus). We investigated the molecular identity of opsins in the pineal organ, and their expression during different life stages. Using RT-PCR we identified two 681-bp gene sequences, named HPO1 and HPO4, in cDNA from adult pineal and whole embryos. The predicted amino acid sequences showed highest identity to the transmembrane regions of teleostean RH2 green cone opsins (HPO1, 72-91%) and SWS-1 UV cone opsins (HPO4, 71-83%). In situ hybridization revealed expression of HPO1 and HPO4 mRNA transcripts in photoreceptors in the pineal organ of embryos, larvae and adults. HPO1 and HPO4 mRNA transcripts were also expressed in the larval retina. Our study provides molecular evidence for short and middle wavelength light sensitive photoreceptors in the pineal organ of Atlantic halibut throughout life, and suggests that pineal photoreception may play an important role during embryonic and larval life stages, especially at the time when the retina does not possesses corresponding photoreceptor capacity.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Animal
- RNA
- Messenger : analysis
- Pineal Body : physiology
- Pineal Body : growth & development
- Photoreceptors
- Vertebrate : physiology
- Opsin : genetics
- Molecular Sequence Data
- Membrane Proteins : physiology
- Membrane Proteins : genetics
- In Situ Hybridization
- Developmental
- Gene Expression Regulation
- Non-U.S. Gov't
- Support
- Flounder : genetics
- Molecular
- Cloning
- Atlantic Ocean
- Amino Acid Sequence
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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