WFRF:(Howells F. M.)
Sökning: WFRF:(Howells F. M.) > Cortical abnormalit...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 07998naa a2201789 4500 | |
| 001 | oai:gup.ub.gu.se/266357 | |
| 003 | SwePub | |
| 008 | 240528s2018 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:137889818 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/2663572 URI |
| 024 | 7 | a https://doi.org/10.1038/mp.2017.732 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1378898182 URI |
| 040 | a (SwePub)gud (SwePub)ki | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Hibar, D. P.4 aut |
| 245 | 1 0 | a Cortical abnormalities in bipolar disorder: An MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group |
| 264 | c 2017-05-02 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2018 |
| 520 | a Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understood. Structural brain differences have been associated with BD, but results from neuroimaging studies have been inconsistent. To address this, we performed the largest study to date of cortical gray matter thickness and surface area measures from brain magnetic resonance imaging scans of 6503 individuals including 1837 unrelated adults with BD and 2582 unrelated healthy controls for group differences while also examining the effects of commonly prescribed medications, age of illness onset, history of psychosis, mood state, age and sex differences on cortical regions. In BD, cortical gray matter was thinner in frontal, temporal and parietal regions of both brain hemispheres. BD had the strongest effects on left pars opercularis (Cohen's d='0.293; P=1.71 × 10 '21), left fusiform gyrus (d='0.288; P=8.25 × 10 '21) and left rostral middle frontal cortex (d='0.276; P=2.99 × 10 '19). Longer duration of illness (after accounting for age at the time of scanning) was associated with reduced cortical thickness in frontal, medial parietal and occipital regions. We found that several commonly prescribed medications, including lithium, antiepileptic and antipsychotic treatment showed significant associations with cortical thickness and surface area, even after accounting for patients who received multiple medications. We found evidence of reduced cortical surface area associated with a history of psychosis but no associations with mood state at the time of scanning. Our analysis revealed previously undetected associations and provides an extensive analysis of potential confounding variables in neuroimaging studies of BD. © 2018 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng |
| 700 | 1 | a Westlye, L. T.4 aut |
| 700 | 1 | a Doan, N. T.4 aut |
| 700 | 1 | a Jahanshad, N.4 aut |
| 700 | 1 | a Cheung, J. W.4 aut |
| 700 | 1 | a Ching, C. R. K.4 aut |
| 700 | 1 | a Versace, A.4 aut |
| 700 | 1 | a Bilderbeck, A. C.u Karolinska Institutet4 aut |
| 700 | 1 | a Uhlmann, A.4 aut |
| 700 | 1 | a Mwangi, B.4 aut |
| 700 | 1 | a Krämer, B.4 aut |
| 700 | 1 | a Overs, B.4 aut |
| 700 | 1 | a Hartberg, C. B.4 aut |
| 700 | 1 | a Abe, C.4 aut |
| 700 | 1 | a Dima, D.4 aut |
| 700 | 1 | a Grotegerd, D.4 aut |
| 700 | 1 | a Sprooten, E.4 aut |
| 700 | 1 | a Ben, E.4 aut |
| 700 | 1 | a Jimenez, E.u Karolinska Institutet4 aut |
| 700 | 1 | a Howells, F. M.4 aut |
| 700 | 1 | a Delvecchio, G.4 aut |
| 700 | 1 | a Temmingh, H.4 aut |
| 700 | 1 | a Starke, J.4 aut |
| 700 | 1 | a Almeida, J. R. C.4 aut |
| 700 | 1 | a Goikolea, J. M.4 aut |
| 700 | 1 | a Houenou, J.4 aut |
| 700 | 1 | a Landén, Mikael,d 1966u Gothenburg University,Göteborgs universitet,Karolinska Institutet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology4 aut0 (Swepub:gu)xlandt |
| 700 | 1 | a Rauer, L.4 aut |
| 700 | 1 | a Abramovic, L.4 aut |
| 700 | 1 | a Bonnin, M.4 aut |
| 700 | 1 | a Ponteduro, M. F.4 aut |
| 700 | 1 | a Keil, M.4 aut |
| 700 | 1 | a Rive, M. M.4 aut |
| 700 | 1 | a Yao, N.4 aut |
| 700 | 1 | a Yalin, N.4 aut |
| 700 | 1 | a Najt, P.4 aut |
| 700 | 1 | a Rosa, P. G.4 aut |
| 700 | 1 | a Redlich, R.4 aut |
| 700 | 1 | a Trost, S.4 aut |
| 700 | 1 | a Hagenaars, S.4 aut |
| 700 | 1 | a Fears, S. C.4 aut |
| 700 | 1 | a Alonso-Lana, S.4 aut |
| 700 | 1 | a Van Erp, T. G. M.4 aut |
| 700 | 1 | a Nickson, T.4 aut |
| 700 | 1 | a Chaim-Avancini, T. M.4 aut |
| 700 | 1 | a Meier, T. B.4 aut |
| 700 | 1 | a Elvsashagen, T.4 aut |
| 700 | 1 | a Haukvik, U. K.4 aut |
| 700 | 1 | a Lee, W. H.4 aut |
| 700 | 1 | a Schene, A. H.4 aut |
| 700 | 1 | a Lloyd, A. J.4 aut |
| 700 | 1 | a Young, A. H.4 aut |
| 700 | 1 | a Nugent, A.4 aut |
| 700 | 1 | a Dale, A. M.4 aut |
| 700 | 1 | a Pfennig, A.4 aut |
| 700 | 1 | a McIntosh, A. M.4 aut |
| 700 | 1 | a Lafer, B.4 aut |
| 700 | 1 | a Baune, B. T.4 aut |
| 700 | 1 | a Ekman, C. J.4 aut |
| 700 | 1 | a Zarate, C. A.4 aut |
| 700 | 1 | a Bearden, C. E.4 aut |
| 700 | 1 | a Henry, C.4 aut |
| 700 | 1 | a Simhandl, C.4 aut |
| 700 | 1 | a McDonald, C.4 aut |
| 700 | 1 | a Bourne, C.4 aut |
| 700 | 1 | a Stein, D. J.4 aut |
| 700 | 1 | a Wolf, D. H.4 aut |
| 700 | 1 | a Cannon, D. M.4 aut |
| 700 | 1 | a Glahn, D. C.4 aut |
| 700 | 1 | a Veltman, D. J.4 aut |
| 700 | 1 | a Pomarol-Clotet, E.4 aut |
| 700 | 1 | a Vieta, E.4 aut |
| 700 | 1 | a Canales-Rodriguez, E. J.4 aut |
| 700 | 1 | a Nery, F. G.4 aut |
| 700 | 1 | a Duran, F. L. S.4 aut |
| 700 | 1 | a Busatto, G. F.4 aut |
| 700 | 1 | a Roberts, G.4 aut |
| 700 | 1 | a Pearlson, G. D.4 aut |
| 700 | 1 | a Goodwin, G. M.4 aut |
| 700 | 1 | a Kugel, H.4 aut |
| 700 | 1 | a Whalley, H. C.4 aut |
| 700 | 1 | a Ruhe, H. G.4 aut |
| 700 | 1 | a Soares, J. C.4 aut |
| 700 | 1 | a Fullerton, J. M.4 aut |
| 700 | 1 | a Rybakowski, J. K.4 aut |
| 700 | 1 | a Savitz, J.4 aut |
| 700 | 1 | a Chaim, K. T.4 aut |
| 700 | 1 | a Fatjó-Vilas, M.4 aut |
| 700 | 1 | a Soeiro-De-Souza, M. G.4 aut |
| 700 | 1 | a Boks, M. P.4 aut |
| 700 | 1 | a Zanetti, M. V.4 aut |
| 700 | 1 | a Otaduy, M. C. G.4 aut |
| 700 | 1 | a Schaufelberger, M. S.4 aut |
| 700 | 1 | a Alda, M.4 aut |
| 700 | 1 | a Ingvar, M.u Karolinska Institutet4 aut |
| 700 | 1 | a Phillips, M. L.4 aut |
| 700 | 1 | a Kempton, M. J.4 aut |
| 700 | 1 | a Bauer, M.4 aut |
| 700 | 1 | a Landén, Mikael,d 1966u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology4 aut0 (Swepub:gu)xlandt |
| 700 | 1 | a Lawrence, N. S.4 aut |
| 700 | 1 | a Van Haren, N. E. M.4 aut |
| 700 | 1 | a Horn, N. R.4 aut |
| 700 | 1 | a Freimer, N. B.4 aut |
| 700 | 1 | a Gruber, O.4 aut |
| 700 | 1 | a Schofield, P. R.4 aut |
| 700 | 1 | a Mitchell, P. B.4 aut |
| 700 | 1 | a Kahn, R. S.4 aut |
| 700 | 1 | a Lenroot, R.4 aut |
| 700 | 1 | a Machado-Vieira, R.4 aut |
| 700 | 1 | a Ophoff, R. A.4 aut |
| 700 | 1 | a Sarró, S.4 aut |
| 700 | 1 | a Frangou, S.4 aut |
| 700 | 1 | a Satterthwaite, T. D.4 aut |
| 700 | 1 | a Hajek, T.4 aut |
| 700 | 1 | a Dannlowski, U.4 aut |
| 700 | 1 | a Malt, U. F.4 aut |
| 700 | 1 | a Arolt, V.4 aut |
| 700 | 1 | a Gattaz, W. F.4 aut |
| 700 | 1 | a Drevets, W. C.4 aut |
| 700 | 1 | a Caseras, X.4 aut |
| 700 | 1 | a Agartz, I.u Karolinska Institutet4 aut |
| 700 | 1 | a Thompson, P. M.4 aut |
| 700 | 1 | a Andreassen, O. A.4 aut |
| 710 | 2 | a Karolinska Institutetb Institutionen för neurovetenskap och fysiologi4 org |
| 773 | 0 | t Molecular Psychiatryd : Springer Science and Business Media LLCg 23:4, s. 932-942q 23:4<932-942x 1359-4184x 1476-5578 |
| 856 | 4 | u https://www.nature.com/articles/mp201773.pdf |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/266357 |
| 856 | 4 8 | u https://doi.org/10.1038/mp.2017.73 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:137889818 |
Hitta mer i SwePub
- Av författaren/redakt...
- Hibar, D. P.
- Westlye, L. T.
- Doan, N. T.
- Jahanshad, N.
- Cheung, J. W.
- Ching, C. R. K.
- visa fler...
- Versace, A.
- Bilderbeck, A. C ...
- Uhlmann, A.
- Mwangi, B.
- Krämer, B.
- Overs, B.
- Hartberg, C. B.
- Abe, C.
- Dima, D.
- Grotegerd, D.
- Sprooten, E.
- Ben, E.
- Jimenez, E.
- Howells, F. M.
- Delvecchio, G.
- Temmingh, H.
- Starke, J.
- Almeida, J. R. C ...
- Goikolea, J. M.
- Houenou, J.
- Landén, Mikael, ...
- Rauer, L.
- Abramovic, L.
- Bonnin, M.
- Ponteduro, M. F.
- Keil, M.
- Rive, M. M.
- Yao, N.
- Yalin, N.
- Najt, P.
- Rosa, P. G.
- Redlich, R.
- Trost, S.
- Hagenaars, S.
- Fears, S. C.
- Alonso-Lana, S.
- Van Erp, T. G. M ...
- Nickson, T.
- Chaim-Avancini, ...
- Meier, T. B.
- Elvsashagen, T.
- Haukvik, U. K.
- Lee, W. H.
- Schene, A. H.
- Lloyd, A. J.
- Young, A. H.
- Nugent, A.
- Dale, A. M.
- Pfennig, A.
- McIntosh, A. M.
- Lafer, B.
- Baune, B. T.
- Ekman, C. J.
- Zarate, C. A.
- Bearden, C. E.
- Henry, C.
- Simhandl, C.
- McDonald, C.
- Bourne, C.
- Stein, D. J.
- Wolf, D. H.
- Cannon, D. M.
- Glahn, D. C.
- Veltman, D. J.
- Pomarol-Clotet, ...
- Vieta, E.
- Canales-Rodrigue ...
- Nery, F. G.
- Duran, F. L. S.
- Busatto, G. F.
- Roberts, G.
- Pearlson, G. D.
- Goodwin, G. M.
- Kugel, H.
- Whalley, H. C.
- Ruhe, H. G.
- Soares, J. C.
- Fullerton, J. M.
- Rybakowski, J. K ...
- Savitz, J.
- Chaim, K. T.
- Fatjó-Vilas, M.
- Soeiro-De-Souza, ...
- Boks, M. P.
- Zanetti, M. V.
- Otaduy, M. C. G.
- Schaufelberger, ...
- Alda, M.
- Ingvar, M.
- Phillips, M. L.
- Kempton, M. J.
- Bauer, M.
- Lawrence, N. S.
- Van Haren, N. E. ...
- Horn, N. R.
- Freimer, N. B.
- Gruber, O.
- Schofield, P. R.
- Mitchell, P. B.
- Kahn, R. S.
- Lenroot, R.
- Machado-Vieira, ...
- Ophoff, R. A.
- Sarró, S.
- Frangou, S.
- Satterthwaite, T ...
- Hajek, T.
- Dannlowski, U.
- Malt, U. F.
- Arolt, V.
- Gattaz, W. F.
- Drevets, W. C.
- Caseras, X.
- Agartz, I.
- Thompson, P. M.
- Andreassen, O. A ...
- visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Klinisk medicin
- och Psykiatri
- Artiklar i publikationen
- Molecular Psychi ...
- Av lärosätet
- Göteborgs universitet
- Karolinska Institutet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
