Sökning: WFRF:(Kubiński Konrad) > Yeast Elf1 factor i...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 02240naa a2200385 4500 | |
001 | oai:DiVA.org:uu-80913 | |
003 | SwePub | |
008 | 060620s2006 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-809132 URI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Kubinski, Konrad4 aut |
245 | 1 0 | a Yeast Elf1 factor is phosphorylated and interacts with protein kinase CK2 |
264 | 1 | c 2006 |
338 | a print2 rdacarrier | |
520 | a One of the biggest group of proteins influenced by protein kinase CK2 is formed by factors engaged in gene expression. Here we have reported recently identified yeast transcription elongation factor Elf1 as a new substrate for both monomeric and tetrameric forms of CK2. Elf1 serves as a substrate for both the recombinant CK2alpha' (K(m) 0.38 microM) and holoenzyme (K(m) 0.13 microM). By MALDI-MS we identified the two serine residues at positions 95 and 117 as the most probable in vitro phosphorylation sites. Coimmunoprecypitation experiments show that Elf1 interacts with catalytic (alpha and alpha') as well as regulatory (beta and beta') subunits of CK2. These data may help to elucidate the role of protein kinase CK2 and Elf1 in the regulation of transcription elongation. | |
653 | a Cloning and overexpression | |
653 | a Mass spectrometry | |
653 | a Phosphorylation | |
653 | a Protein-protein interaction | |
653 | a Protein kinase CK2 | |
653 | a Transcription | |
653 | a Transcription factor Elf1 | |
653 | a Yeast | |
700 | 1 | a Zielinski, Rafal4 aut |
700 | 1 | a Hellman, Ulfu Uppsala universitet,Ludwiginstitutet för cancerforskning4 aut0 (Swepub:uu)ulfhm |
700 | 1 | a Mazur, Elzbieta4 aut |
700 | 1 | a Szyszka, Ryszard4 aut |
710 | 2 | a Uppsala universitetb Ludwiginstitutet för cancerforskning4 org |
773 | 0 | t Journal of Biochemistry and Molecular Biologyg 39:3, s. 311-318q 39:3<311-318x 1225-8687x 0219-1024 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=16756761&dopt=Citation |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-80913 |
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