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FältnamnIndikatorerMetadata
00004635naa a2200469 4500
001oai:lup.lub.lu.se:4b4b4c33-b612-48be-8d02-8603daec14a5
003SwePub
008170123s2017 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:136637020
0247 a https://lup.lub.lu.se/record/4b4b4c33-b612-48be-8d02-8603daec14a52 URI
0247 a https://doi.org/10.1016/j.jpedsurg.2017.01.0012 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1366370202 URI
040 a (SwePub)lud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Bjørnland, Kristinu University of Oslo4 aut
2451 0a A Nordic multicenter survey of long-term bowel function after transanal endorectal pull-through in 200 patients with rectosigmoid Hirschsprung disease
264 1b Elsevier BV,c 2017
520 a OBJECTIVE: Transanal endorectal pull-through (ERPT) is the most popular technique to treat Hirschsprung disease (HD). Still, there is limited knowledge on long-term bowel function. This cross-sectional, multicenter study assessed long-term bowel function in a large HD population and examined predictors of poor outcome.METHODS: Patients older than four years or their parents filled out a validated questionnaire on bowel function. Clinical details were recorded retrospectively from medical records.RESULTS: 73/200 (37%) patients reported absolutely no impaired bowel function, meaning no constipation, fecal accidents, stoma, appendicostomy or need for enemas. Seven (4%) had a stoma, and 33 (17%) used antegrade or rectal colonic enemas. Most disarrangements of fecal control and constipation were significantly less common in older age group, but abnormal defecation frequency and social problems remained unchanged. Syndromic patients (n=31) experienced frequent fecal accidents (46%) more often than nonsyndromic (14%, P<0.001). Having a syndrome (adjusted OR 5.6, 95% CI 2.1-15, P=0.001) or a complete transanal ERPT (adjusted OR 2.4, 95% CI 1.1-5.7, P=0.038) was significantly associated with poor outcome defined as having a stoma, an appendicostomy, daily fecal accidents or need of regular rectal wash outs.CONCLUSION: A significant number of HD patients experience bowel problems many years after definite surgery. Fecal control was significantly better in older than younger HD patients, but some continued to have considerable bowel problems also as adults. A total transanal ERPT was associated with poorer outcome. Long-term follow-up of HD patients is warranted. Prognosis Study: Level II.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
7001 a Pakarinen, Mikko Pu University of Helsinki4 aut
7001 a Stenstrøm, Pernillau Lund University,Lunds universitet,Barnkirurgi,Forskargrupper vid Lunds universitet,Pediatric surgery,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-pes
7001 a Stensrud, Kjetil Ju University of Oslo4 aut
7001 a Neuvonen, Mallau University of Helsinki4 aut
7001 a Granström, Anna Lu Karolinska Institutet4 aut
7001 a Graneli, Christinau Lund University,Lunds universitet,Barnkirurgi,Forskargrupper vid Lunds universitet,Pediatric surgery,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-crg
7001 a Pripp, Are Hu Oslo university hospital4 aut
7001 a Arnbjörnsson, Einaru Lund University,Lunds universitet,Barnkirurgi,Forskargrupper vid Lunds universitet,Pediatric surgery,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-eas
7001 a Emblem, Ragnhildu University of Oslo4 aut
7001 a Wester, Tomasu Karolinska Institutet4 aut
7001 a Rintala, Risto Ju University of Helsinki4 aut
7102 a University of Oslob University of Helsinki4 org
7102 a Nordic Pediatric Surgery Study Consortium
7730 t Journal of Pediatric Surgeryd : Elsevier BVg 52:9, s. 1458-1464q 52:9<1458-1464x 1531-5037x 0022-3468
8564 u http://dx.doi.org/10.1016/j.jpedsurg.2017.01.001y FULLTEXT
8564 u https://helda.helsinki.fi/bitstream/10138/299387/1/1_s2.0_S0022346817300015_main.pdf
8564 8u https://lup.lub.lu.se/record/4b4b4c33-b612-48be-8d02-8603daec14a5
8564 8u https://doi.org/10.1016/j.jpedsurg.2017.01.001
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:136637020

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